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Background: Living cells of many types need to move in response to external stimuli in order to accomplish their functional tasks; these tasks range from wound healing to immune response to fertilization. While the directional motion is…

Cell Behavior · Quantitative Biology 2015-05-28 Inbal Hecht , Herbert Levine , Wouter-Jan Rappel , Eshel Ben-Jacob

In this article, we propose a general framework to study the dynamics and topology of cellular networks that capture the geometry of cell packings in two-dimensional tissues. Such epithelia undergo large-scale deformation during…

Tissues and Organs · Quantitative Biology 2017-09-08 Matthias Merkel , Raphaël Etournay , Marko Popović , Guillaume Salbreux , Suzanne Eaton , Frank Jülicher

Electromagnetic metasurfaces offer the capability to realize almost arbitrary power conserving field transformations. These field transformations are governed by the generalized sheet transition conditions, which relate the tangential…

Applied Physics · Physics 2020-11-19 Stewart Pearson , Sean V. Hum

In biological cells and novel diagnostic devices biochemical receptors need to be sensitive to extremely small concentration changes of signaling molecules. The accuracy of such molecular signaling is ultimately limited by the counting…

Subcellular Processes · Quantitative Biology 2023-04-06 Aljaz Godec , Ralf Metzler

We propose a two-scale model to resolve essential features of developmental tissue deformations. The model couples individual cellular behavior to the mechanics at tissue scale. This is realized by a multiphase-field model addressing the…

Soft Condensed Matter · Physics 2025-06-25 Lea Happel , Axel Voigt

We propose the autofocus convolutional layer for semantic segmentation with the objective of enhancing the capabilities of neural networks for multi-scale processing. Autofocus layers adaptively change the size of the effective receptive…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Yao Qin , Konstantinos Kamnitsas , Siddharth Ancha , Jay Nanavati , Garrison Cottrell , Antonio Criminisi , Aditya Nori

Shape sensing of medical continuum robots is important both for closed-loop control as well as for enabling the clinician to visualize the robot inside the body. There is a need for inexpensive, but accurate shape sensing technologies. This…

Robotics · Computer Science 2024-10-22 Giovanni Pittiglio , Abdulhamit Donder , Pierre E. Dupont

The edge detection task is essential in image processing aiming to extract relevant information from an image. One recurring problem in this task is the weaknesses found in some detectors, such as the difficulty in detecting loose edges and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Vinícius Ferraria , Eurico Ruivo

Living cells sense noisy biochemical signals crucial for survival, yet models incorporating intracellular signaling are limited. This study examines how cells sense chemotactic concentrations through phosphorylation readouts in Ca2+…

Subcellular Processes · Quantitative Biology 2025-08-22 Swoyam Srirupa , Pradeep , Vaibhav Wasnik

3D cell tracking in a living organism has a crucial role in live cell image analysis. Cell tracking in C. elegans has two difficulties. First, cell migration in a consecutive frame is large since they move their head during scanning.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Kaito Shiku , Hiromitsu Shirai , Takeshi Ishihara , Ryoma Bise

A shape sensitive, variational approach for the matching of surfaces considered as thin elastic shells is investigated. The elasticity functional to be minimized takes into account two different types of nonlinear energies: a membrane…

Optimization and Control · Mathematics 2021-06-09 José A. Iglesias , Martin Rumpf , Otmar Scherzer

We investigate single-cell directional sensing from diffusing chemoattractant signals released by a localized source. We focus on the low-concentration regime in which receptor activity is discrete and cellular decisions are made on…

Cell Behavior · Quantitative Biology 2026-03-12 Vincent Fiorino , Sean D. Lawley , Alan E. Lindsay

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

The interplay between large antenna apertures and high carrier frequencies in future wireless systems gives rise to near-field communications, where the curvature of spherical wavefronts renders traditional far-field beamforming models…

Signal Processing · Electrical Eng. & Systems 2025-12-02 Panagiotis Gavriilidis , George C. Alexandropoulos

Summary: Errors in gradient trajectories introduce significant artifacts and distortions in magnetic resonance images, particularly in non-Cartesian imaging sequences, where imperfect gradient waveforms can greatly reduce image quality.…

Medical Physics · Physics 2025-06-19 Jonathan B. Martin , Hannah E. Alderson , John C. Gore , Mark D. Does , Kevin D. Harkins

This note works out an advection-diffusion approximation to the density of a population of E. coli bacteria undergoing chemotaxis in a one-dimensional space. Simulations show the high quality of predictions under a shallow-gradient regime.

Quantitative Methods · Quantitative Biology 2013-02-12 Zahra Aminzare , Eduardo D. Sontag

We investigate a continuum mechanical model for an adherent cell on two dimensional adhesive micropatterned substrates. The cell is modeled as an isotropic and homogeneous elastic material subject to uniform internal contractile stresses.…

Biological Physics · Physics 2013-12-30 Shiladitya Banerjee , Rastko Sknepnek , M. Cristina Marchetti

This study addresses the challenge of classifying cell shapes from noisy contours, such as those obtained through cell instance segmentation of histological images. We assess the performance of various features for shape classification,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Enrico Grisan

The global scales of solar convection are studied through three-dimensional simulations of compressible convection carried out in spherical shells of rotating fluid which extend from the base of the convection zone to within 15 Mm of the…

Astrophysics · Physics 2009-11-13 Mark S. Miesch , Allan Sacha Brun , Marc L. Derosa , Juri Toomre

We propose a PDE-constrained shape registration algorithm that captures the deformation and growth of biological tissue from imaging data. Shape registration is the process of evaluating optimum alignment between pairs of geometries through…

Biological Physics · Physics 2022-04-07 Aishwarya Pawar , Linlin Li , Arun K Gosain , David M Umulis , Adrian B Tepole