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Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Dingyu Wang , Zimu Yuan , Jiajun Liu , Shanggui Liu , Nan Zhou , Tianxing Xu , Di Huang , Dong Jiang

Existing tasks fall short in evaluating reasoning ability of Large Language Models (LLMs) in an interactive, unknown environment. This deficiency leads to the isolated assessment of deductive, inductive, and abductive reasoning, neglecting…

Artificial Intelligence · Computer Science 2026-05-07 Congchi Yin , Tianyi Wu , Yankai Shu , Alex Gu , Yunhan Wang , Jun Shao , Xun Jiang , Piji Li

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

Computation and Language · Computer Science 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao

Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

Information Retrieval · Computer Science 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

Large language models (LLMs) have demonstrated remarkable performance on various medical benchmarks, but their capabilities across different cognitive levels remain underexplored. Inspired by Bloom's Taxonomy, we propose a…

Computation and Language · Computer Science 2025-06-11 Yuxuan Zhou , Xien Liu , Chenwei Yan , Chen Ning , Xiao Zhang , Boxun Li , Xiangling Fu , Shijin Wang , Guoping Hu , Yu Wang , Ji Wu

Despite the remarkable advancements and widespread applications of deep neural networks, their ability to perform reasoning tasks remains limited, particularly in domains requiring structured, abstract thought. In this paper, we investigate…

Computation and Language · Computer Science 2025-09-16 Satyam Goyal , Soham Dan

Large language models (LLMs), a recent advance in deep learning and machine intelligence, have manifested astonishing capacities, now considered among the most promising for artificial general intelligence. With human-like capabilities,…

Artificial Intelligence · Computer Science 2025-09-19 Zhilun Zhou , Jing Yi Wang , Nicholas Sukiennik , Chen Gao , Fengli Xu , Yong Li , James Evans

Large Language Models (LLMs) have demonstrated remarkable capabilities in complex tasks. Recent advancements in Large Reasoning Models (LRMs), such as OpenAI o1 and DeepSeek-R1, have further improved performance in System-2 reasoning…

Computation and Language · Computer Science 2025-08-25 Yang Sui , Yu-Neng Chuang , Guanchu Wang , Jiamu Zhang , Tianyi Zhang , Jiayi Yuan , Hongyi Liu , Andrew Wen , Shaochen Zhong , Na Zou , Hanjie Chen , Xia Hu

Language has long been conceived as an essential tool for human reasoning. The breakthrough of Large Language Models (LLMs) has sparked significant research interest in leveraging these models to tackle complex reasoning tasks. Researchers…

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

Computation and Language · Computer Science 2025-11-13 Jonathan Kim , Anna Podlasek , Kie Shidara , Feng Liu , Ahmed Alaa , Danilo Bernardo

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Purpose: To evaluate the accuracy and reasoning ability of DeepSeek-R1 and three other recently released large language models (LLMs) in bilingual complex ophthalmology cases. Methods: A total of 130 multiple-choice questions (MCQs) related…

Computation and Language · Computer Science 2025-02-26 Pusheng Xu , Yue Wu , Kai Jin , Xiaolan Chen , Mingguang He , Danli Shi

Large language models (LLMs) have shown remarkable improvements in reasoning and many existing benchmarks have been addressed by models such as o1 and o3 either fully or partially. However, a majority of these benchmarks emphasize deductive…

Machine Learning · Computer Science 2025-05-15 Wenyue Hua , Tyler Wong , Sun Fei , Liangming Pan , Adam Jardine , William Yang Wang

The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios. To enable…

Computation and Language · Computer Science 2025-05-30 Yakun Zhu , Zhongzhen Huang , Linjie Mu , Yutong Huang , Wei Nie , Jiaji Liu , Shaoting Zhang , Pengfei Liu , Xiaofan Zhang

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

The emergence of Large Language Models (LLMs) has fundamentally transformed natural language processing, making them indispensable across domains ranging from conversational systems to scientific exploration. However, their pre-trained…

In this technical report, we introduce OpenR, an open-source framework designed to integrate key components for enhancing the reasoning capabilities of large language models (LLMs). OpenR unifies data acquisition, reinforcement learning…

Artificial Intelligence · Computer Science 2024-10-15 Jun Wang , Meng Fang , Ziyu Wan , Muning Wen , Jiachen Zhu , Anjie Liu , Ziqin Gong , Yan Song , Lei Chen , Lionel M. Ni , Linyi Yang , Ying Wen , Weinan Zhang

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

Multimodal large language models (MLLMs) hold significant potential in medical applications, including disease diagnosis and clinical decision-making. However, these tasks require highly accurate, context-sensitive, and professionally…

Computation and Language · Computer Science 2025-09-01 Meidan Ding , Jipeng Zhang , Wenxuan Wang , Cheng-Yi Li , Wei-Chieh Fang , Hsin-Yu Wu , Haiqin Zhong , Wenting Chen , Linlin Shen