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Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Guo Tang , Songhan Jiang , Jinpeng Lu , Linghan Cai , Yongbing Zhang

Surgical scene understanding and multi-tasking learning are crucial for image-guided robotic surgery. Training a real-time robotic system for the detection and segmentation of high-resolution images provides a challenging problem with the…

Computer Vision and Pattern Recognition · Computer Science 2020-10-19 Mobarakol Islam , Vibashan VS , Hongliang Ren

Image-based brain cancer prediction models, based on radiomics, quantify the radiologic phenotype from magnetic resonance imaging (MRI). However, these features are difficult to reproduce because of variability in acquisition and…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Xuan Xu , Prateek Prasanna

The ability to generalize quickly from few observations is crucial for intelligent systems. In this paper we introduce APL, an algorithm that approximates probability distributions by remembering the most surprising observations it has…

Machine Learning · Computer Science 2019-02-08 Tiago Ramalho , Marta Garnelo

A framework is introduced for actively and adaptively solving a sequence of machine learning problems, which are changing in bounded manner from one time step to the next. An algorithm is developed that actively queries the labels of the…

Machine Learning · Computer Science 2018-05-31 Yuheng Bu , Jiaxun Lu , Venugopal V. Veeravalli

Lifelong learning (LL) aims to continuously acquire new knowledge while retaining previously learned knowledge. A central challenge in LL is the stability-plasticity dilemma, which requires models to balance the preservation of previous…

Machine Learning · Computer Science 2025-03-11 Ruiyu Wang , Sen Wang , Xinxin Zuo , Qiang Sun

Over the past decade, the use of machine learning (ML) models in healthcare applications has rapidly increased. Despite high performance, modern ML models do not always capture patterns the end user requires. For example, a model may…

Deep learning models have demonstrated great potential in medical 3D imaging, but their development is limited by the expensive, large volume of annotated data required. Active learning (AL) addresses this by training a model on a subset of…

Pool-based active learning (AL) is a promising technology for increasing data-efficiency of machine learning models. However, surveys show that performance of recent AL methods is very sensitive to the choice of dataset and training…

Machine Learning · Computer Science 2023-09-12 Tim Bakker , Herke van Hoof , Max Welling

Effective protein representation learning is crucial for predicting protein functions. Traditional methods often pretrain protein language models on large, unlabeled amino acid sequences, followed by finetuning on labeled data. While…

Biomolecules · Quantitative Biology 2024-09-05 Jiangbin Zheng , Stan Z. Li

Managing heterogeneous datasets that vary in complexity, size, and similarity in continual learning presents a significant challenge. Task-agnostic continual learning is necessary to address this challenge, as datasets with varying…

Machine Learning · Computer Science 2024-01-09 Yuqing Zhao , Divya Saxena , Jiannong Cao

The hybrid nature of multi-contact robotic systems, due to making and breaking contact with the environment, creates significant challenges for high-quality control. Existing model-based methods typically rely on either good prior knowledge…

Robotics · Computer Science 2024-03-05 Wei-Cheng Huang , Alp Aydinoglu , Wanxin Jin , Michael Posa

The computational burden and inherent redundancy of large-scale datasets challenge the training of contemporary machine learning models. Data pruning offers a solution by selecting smaller, informative subsets, yet existing methods…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Feiyang Kang , Nadine Chang , Maying Shen , Marc T. Law , Rafid Mahmood , Ruoxi Jia , Jose M. Alvarez

Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-17 Conghao Xiong , Hao Chen , Hao Zheng , Dong Wei , Yefeng Zheng , Joseph J. Y. Sung , Irwin King

Risk stratification is a key tool in clinical decision-making, yet current approaches often fail to translate sophisticated survival analysis into actionable clinical criteria. We present a novel method for unsupervised machine learning…

In modern biomedical and econometric studies, longitudinal processes are often characterized by complex time-varying associations and abrupt regime shifts that are shared across correlated outcomes. Standard functional data analysis (FDA)…

Methodology · Statistics 2026-01-28 Baolin Chen , Mengfei Ran

Recently, we have witnessed impressive achievements in cancer survival analysis by integrating multimodal data, e.g., pathology images and genomic profiles. However, the heterogeneity and high dimensionality of these modalities pose…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Huajun Zhou , Fengtao Zhou , Hao Chen

Accurately predicting the survival rate of cancer patients is crucial for aiding clinicians in planning appropriate treatment, reducing cancer-related medical expenses, and significantly enhancing patients' quality of life. Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Liangrui Pan , Yijun Peng , Yan Li , Xiang Wang , Wenjuan Liu , Liwen Xu , Qingchun Liang , Shaoliang Peng

Learning good representation of giga-pixel level whole slide pathology images (WSI) for downstream tasks is critical. Previous studies employ multiple instance learning (MIL) to represent WSIs as bags of sampled patches because, for most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Chunyuan Li , Xinliang Zhu , Jiawen Yao , Junzhou Huang

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham