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The rapid growth of Large Language Models (LLMs) has been a driving force in transforming various domains, reshaping the artificial general intelligence landscape. However, the increasing computational and memory demands of these models…

Computation and Language · Computer Science 2024-04-22 Tianyu Ding , Tianyi Chen , Haidong Zhu , Jiachen Jiang , Yiqi Zhong , Jinxin Zhou , Guangzhi Wang , Zhihui Zhu , Ilya Zharkov , Luming Liang

We consider the protein sequence engineering problem, which aims to find protein sequences with high fitness levels, starting from a given wild-type sequence. Directed evolution has been a dominating paradigm in this field which has an…

Machine Learning · Computer Science 2025-01-20 Yinkai Wang , Jiaxing He , Yuanqi Du , Xiaohui Chen , Jianan Canal Li , Li-Ping Liu , Xiaolin Xu , Soha Hassoun

Large language models (LLMs) are beginning to reshape how chemists plan and run reactions in organic synthesis. Trained on millions of reported transformations, these text-based models can propose synthetic routes, forecast reaction…

Artificial Intelligence · Computer Science 2025-08-08 Kartar Kumar Lohana Tharwani , Rajesh Kumar , Sumita , Numan Ahmed , Yong Tang

Large language models (LLMs) are becoming increasingly better at a wide range of Natural Language Processing tasks (NLP), such as text generation and understanding. Recently, these models have extended their capabilities to coding tasks,…

Machine Learning · Computer Science 2024-10-23 Nishat Raihan , Mohammed Latif Siddiq , Joanna C. S. Santos , Marcos Zampieri

The advent of Large Language Models (LLMs) has significantly reshaped the trajectory of the AI revolution. Nevertheless, these LLMs exhibit a notable limitation, as they are primarily adept at processing textual information. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Akash Ghosh , Arkadeep Acharya , Sriparna Saha , Vinija Jain , Aman Chadha

The advent of large language models marks a revolutionary breakthrough in artificial intelligence. With the unprecedented scale of training and model parameters, the capability of large language models has been dramatically improved,…

Information Retrieval · Computer Science 2025-01-16 Jin Chen , Zheng Liu , Xu Huang , Chenwang Wu , Qi Liu , Gangwei Jiang , Yuanhao Pu , Yuxuan Lei , Xiaolong Chen , Xingmei Wang , Defu Lian , Enhong Chen

Large language models (LLMs) are a class of language models that have demonstrated outstanding performance across a range of natural language processing (NLP) tasks and have become a highly sought-after research area, because of their…

Digital Libraries · Computer Science 2023-04-06 Lizhou Fan , Lingyao Li , Zihui Ma , Sanggyu Lee , Huizi Yu , Libby Hemphill

Although traditional statistical techniques and machine learning methods have contributed significantly to genetics and, in particular, inherited disease diagnosis, they often struggle with complex, high-dimensional data, a challenge now…

Machine Learning · Computer Science 2025-08-29 Anton Changalidis , Yury Barbitoff , Yulia Nasykhova , Andrey Glotov

Large Language Model (LLM) has transformative potential in various domains, including recommender systems (RS). There have been a handful of research that focuses on empowering the RS by LLM. However, previous efforts mainly focus on LLM as…

Information Retrieval · Computer Science 2025-03-11 Qidong Liu , Xiangyu Zhao , Yuhao Wang , Yejing Wang , Zijian Zhang , Yuqi Sun , Xiang Li , Maolin Wang , Pengyue Jia , Chong Chen , Wei Huang , Feng Tian

Multimodal recommender systems (MRS) integrate heterogeneous user and item data, such as text, images, and structured information, to enhance recommendation performance. The emergence of large language models (LLMs) introduces new…

Information Retrieval · Computer Science 2025-05-16 Alejo Lopez-Avila , Jinhua Du

Large language models (LLMs) have shown significant potential to change how we write, communicate, and create, leading to rapid adoption across society. This dissertation examines how individuals and institutions are adapting to and…

Computation and Language · Computer Science 2025-06-24 Weixin Liang

Large language models (LLMs) and transformer-based architectures are increasingly utilized for source code analysis. As software systems grow in complexity, integrating LLMs into code analysis workflows becomes essential for enhancing…

Software Engineering · Computer Science 2025-03-25 Hamed Jelodar , Mohammad Meymani , Roozbeh Razavi-Far

Large Language Models (LLMs), AI-driven models that can achieve general-purpose language understanding and generation, have emerged as a transformative force, revolutionizing fields well beyond Natural Language Processing (NLP) and…

Information Theory · Computer Science 2024-02-27 Ali Maatouk , Nicola Piovesan , Fadhel Ayed , Antonio De Domenico , Merouane Debbah

This paper provides a comprehensive survey of the latest research on multilingual large language models (MLLMs). MLLMs not only are able to understand and generate language across linguistic boundaries, but also represent an important…

Computation and Language · Computer Science 2024-11-20 Shaolin Zhu , Supryadi , Shaoyang Xu , Haoran Sun , Leiyu Pan , Menglong Cui , Jiangcun Du , Renren Jin , António Branco , Deyi Xiong

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Large language models (LLMs) have revolutionized natural language processing with their exceptional understanding, synthesizing, and reasoning capabilities. However, deploying LLMs on resource-constrained edge devices presents significant…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-25 Yue Zheng , Yuhao Chen , Bin Qian , Xiufang Shi , Yuanchao Shu , Jiming Chen

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

This paper explores the potential opportunities, risks, and challenges associated with the use of large language models (LLMs) in sports science and medicine. LLMs are large neural networks with transformer style architectures trained on…

Computation and Language · Computer Science 2023-05-09 Mark Connor , Michael O'Neill