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Imperfect labels are ubiquitous in real-world datasets and seriously harm the model performance. Several recent effective methods for handling noisy labels have two key steps: 1) dividing samples into cleanly labeled and wrongly labeled…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Wenkai Chen , Chuang Zhu , Yi Chen , Mengting Li , Tiejun Huang

It is tempting to think that machines are less prone to unfairness and prejudice. However, machine learning approaches compute their outputs based on data. While biases can enter at any stage of the development pipeline, models are…

Computer Vision and Pattern Recognition · Computer Science 2020-12-07 Patrick Esser , Robin Rombach , Björn Ommer

One of the focus areas of modern scientific research is to reveal mysteries related to genes and their interactions. The dynamic interactions between genes can be encoded into a gene regulatory network (GRN), which can be used to gain…

Optimization and Control · Mathematics 2020-07-16 Atte Aalto , Lauri Viitasaari , Pauliina Ilmonen , Laurent Mombaerts , Jorge Goncalves

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

Predicting phenotypes from gene expression data is a crucial task in biomedical research, enabling insights into disease mechanisms, drug responses, and personalized medicine. Traditional machine learning and deep learning rely on…

Machine Learning · Computer Science 2025-09-18 Kevin Dradjat , Massinissa Hamidi , Pierre Bartet , Blaise Hanczar

Accurately reconstructing Gene Regulatory Networks (GRNs) is crucial for understanding gene functions and disease mechanisms. Single-cell RNA sequencing (scRNA-seq) technology provides vast data for computational GRN reconstruction. Since…

Molecular Networks · Quantitative Biology 2025-12-16 Rijie Xi , Weikang Xu , Wei Xiong , Yuannong Ye , Bin Zhao

Gene regulation is a complex process involving the role of several genomic elements which work in concert to drive spatio-temporal expression. The experimental characterization of gene regulatory elements is a very complex and…

Genomics · Quantitative Biology 2007-10-11 Arvind Rao , Alfred O. Hero , David J. States , James Douglas Engel

Graph representation learning is a fundamental research issue in various domains of applications, of which the inductive learning problem is particularly challenging as it requires models to generalize to unseen graph structures during…

Machine Learning · Computer Science 2024-03-27 Hanxuan Yang , Zhaoxin Yu , Qingchao Kong , Wei Liu , Wenji Mao

The rapid advancement of deep learning has facilitated the automated processing of electron microscopy (EM) big data stacks. However, designing a framework that eliminates manual labeling and adapts to domain gaps remains challenging.…

Materials Science · Physics 2024-07-30 Wenhao Yuan , Bingqing Yao , Shengdong Tan , Fengqi You , Qian He

With the rapidly growing model complexity and data volume, training deep generative models (DGMs) for better performance has becoming an increasingly more important challenge. Previous research on this problem has mainly focused on…

Machine Learning · Computer Science 2021-12-08 Yufan Zhou , Chunyuan Li , Changyou Chen , Jinhui Xu

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Semi-supervised learning (SSL) is a promising approach for training deep classification models using labeled and unlabeled datasets. However, existing SSL methods rely on a large unlabeled dataset, which may not always be available in many…

Machine Learning · Computer Science 2023-09-29 Shin'ya Yamaguchi

Recently, using large language models (LLMs) for data augmentation has led to considerable improvements in unsupervised sentence embedding models. However, existing methods encounter two primary challenges: limited data diversity and high…

Computation and Language · Computer Science 2025-10-07 Peichao Lai , Zhengfeng Zhang , Wentao Zhang , Fangcheng Fu , Bin Cui

Inference of gene regulatory network from expression data is a challenging task. Many methods have been developed to this purpose but a comprehensive evaluation that covers unsupervised, semi-supervised and supervised methods, and provides…

Molecular Networks · Quantitative Biology 2013-01-08 Stefan R. Maetschke , Piyush B. Madhamshettiwar , Melissa J. Davis , Mark A. Ragan

Ever-larger language models with ever-increasing capabilities are by now well-established text processing tools. Alas, information extraction tasks such as named entity recognition are still largely unaffected by this progress as they are…

Computation and Language · Computer Science 2023-08-16 Tobias Deußer , Lars Hillebrand , Christian Bauckhage , Rafet Sifa

Embodied Vision-Language Models (VLMs) have demonstrated impressive performance and generalization in robotics, particularly within Vision-Language-Action frameworks. However, a significant gap remains between the high-level semantic focus…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Ruowen Zhao , Bangguo Li , Zuyan Liu , Yinan Liang , Junliang Ye , Fangfu Liu , Diankun Wu , Zhengyi Wang , Xumin Yu , Yongming Rao , Han Hu , Jun Zhu

This paper introduces a deep learning enabled generative sensing framework which integrates low-end sensors with computational intelligence to attain a high recognition accuracy on par with that attained with high-end sensors. The proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Lina Karam , Tejas Borkar , Yu Cao , Junseok Chae

Deep generative models (DGMs) are data-eager because learning a complex model on limited data suffers from a large variance and easily overfits. Inspired by the classical perspective of the bias-variance tradeoff, we propose regularized…

Machine Learning · Computer Science 2023-04-11 Yong Zhong , Hongtao Liu , Xiaodong Liu , Fan Bao , Weiran Shen , Chongxuan Li

Disentangled generative models map a latent code vector to a target space, while enforcing that a subset of the learned latent codes are interpretable and associated with distinct properties of the target distribution. Recent advances have…

Machine Learning · Computer Science 2020-08-10 Zinan Lin , Kiran Koshy Thekumparampil , Giulia Fanti , Sewoong Oh

Multi-view learning is widely applied to real-life datasets, such as multiple omics biological data, but it often suffers from both missing views and missing labels. Prior probabilistic approaches addressed the missing view problem by using…

Machine Learning · Computer Science 2025-08-18 Yiyang Shen , Weiran Wang
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