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Recent improvements in convolutional neural network (CNN)-based single image super-resolution (SISR) methods rely heavily on fabricating network architectures, rather than finding a suitable training algorithm other than simply minimizing…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 SeongUk Park , Nojun Kwak

Clustering of single-cell RNA sequencing (scRNA-seq) datasets can give key insights into the biological functions of cells. Therefore, it is not surprising that network-based community detection methods (one of the better clustering…

Methodology · Statistics 2026-02-17 Chetkar Jha , Mingyao Li , Ian Barnett

This work introduces a novel knowledge distillation framework for classification tasks where information on existing subclasses is available and taken into consideration. In classification tasks with a small number of classes or binary…

Machine Learning · Computer Science 2022-07-19 Ahmad Sajedi , Yuri A. Lawryshyn , Konstantinos N. Plataniotis

Single cell combinatorial indexing RNA sequencing (sci-RNA-seq) is a powerful method for recovering gene expression data from an exponentially scalable number of individual cells or nuclei. However, sci-RNA-seq is a complex protocol that…

Dataset distillation (DD) entails creating a refined, compact distilled dataset from a large-scale dataset to facilitate efficient training. A significant challenge in DD is the dependency between the distilled dataset and the neural…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yunlong Zhao , Xiaoheng Deng , Xiu Su , Hongyan Xu , Xiuxing Li , Yijing Liu , Shan You

Stochastic Gradient Decent (SGD) is one of the core techniques behind the success of deep neural networks. The gradient provides information on the direction in which a function has the steepest rate of change. The main problem with basic…

Medical foundation models pre-trained on large-scale datasets have demonstrated powerful versatile capabilities for various tasks. However, due to the gap between pre-training tasks (or modalities) and downstream tasks (or modalities), the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Yuhang Zhou , Siyuan Du , Haolin Li , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Generative Adversarial Networks (GANs) achieve excellent performance in generative tasks, such as image super-resolution, but their computational requirements make difficult their deployment on resource-constrained devices. While knowledge…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Nikolaos Kaparinos , Vasileios Mezaris

Large Language Models (LLMs) demonstrate exceptional reasoning capabilities, often achieving state-of-the-art performance in various tasks. However, their substantial computational and memory demands, due to billions of parameters, hinder…

Computation and Language · Computer Science 2024-11-25 Xunyu Zhu , Jian Li , Can Ma , Weiping Wang

Structure-based drug design (SBDD) faces a fundamental scaling fidelity dilemma: rich pocket-aware conditioning captures interaction geometry but can be costly, often scales quadratically ($O(L^2)$) or worse with protein length ($L$), while…

Machine Learning · Computer Science 2026-02-02 Samyak Sanghvi , Nishant Ranjan , Tarak Karmakar

Medical data often exhibits distribution shifts, which cause test-time performance degradation for deep learning models trained using standard supervised learning pipelines. This challenge is addressed in the field of Domain Generalization…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Aleksandr Matsun , Numan Saeed , Fadillah Adamsyah Maani , Mohammad Yaqub

Single-cell RNA sequencing allows the quantification of gene expression at the individual cell level, enabling the study of cellular heterogeneity and gene expression dynamics. Dimensionality reduction is a common preprocessing step…

Computation · Statistics 2025-10-14 Cristian Castiglione , Alexandre Segers , Lieven Clement , Davide Risso

Recent advances in knowledge distillation (KD) have enabled smaller student models to approach the performance of larger teacher models. However, popular methods such as supervised KD and on-policy KD, are adversely impacted by the…

Computation and Language · Computer Science 2025-04-29 Wenda Xu , Rujun Han , Zifeng Wang , Long T. Le , Dhruv Madeka , Lei Li , William Yang Wang , Rishabh Agarwal , Chen-Yu Lee , Tomas Pfister

Knowledge distillation (KD) in transformers often faces challenges due to misalignment in the number of attention heads between teacher and student models. Existing methods either require identical head counts or introduce projectors to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Zhaodong Bing , Linze Li , Jiajun Liang

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu

While deep learning techniques have proven successful in image-related tasks, the exponentially increased data storage and computation costs become a significant challenge. Dataset distillation addresses these challenges by synthesizing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Zhe Li , Weitong Zhang , Sarah Cechnicka , Bernhard Kainz

We propose Score-of-Mixture Training (SMT), a novel framework for training one-step generative models by minimizing a class of divergences called the $\alpha$-skew Jensen--Shannon divergence. At its core, SMT estimates the score of mixture…

Machine Learning · Computer Science 2025-07-16 Tejas Jayashankar , J. Jon Ryu , Gregory Wornell

Single-cell RNA sequencing (scRNA-seq) enables the study of cellular heterogeneity. Yet, clustering accuracy, and with it downstream analyses based on cell labels, remain challenging due to measurement noise and biological variability. In…

Machine Learning · Computer Science 2026-03-03 Dominik Meier , Shixing Yu , Sagnik Nandy , Promit Ghosal , Kyra Gan

In the medical field, the limited availability of large-scale datasets and labor-intensive annotation processes hinder the performance of deep models. Diffusion-based generative augmentation approaches present a promising solution to this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Xinrui Zhou , Yuhao Huang , Haoran Dou , Shijing Chen , Ao Chang , Jia Liu , Weiran Long , Jian Zheng , Erjiao Xu , Jie Ren , Alejandro F. Frangi , Ruobing Huang , Jun Cheng , Xiaomeng Li , Wufeng Xue , Dong Ni

Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of cellular heterogeneity, enabling detailed molecular profiling at the individual cell level. However, integrating high-dimensional single-cell data into causal mediation…

Methodology · Statistics 2025-10-01 Seungjun Ahn , Li Chen , Maaike van Gerwen , Panos Roussos , Zhigang Li
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