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The knowledge of potentially druggable binding sites on proteins is an important preliminary step towards the discovery of novel drugs. The computational prediction of such areas can be boosted by following the recent major advances in the…

Biomolecules · Quantitative Biology 2021-02-17 Stelios K. Mylonas , Apostolos Axenopoulos , Petros Daras

Identification of drug-target interactions (DTIs) plays a key role in drug discovery. The high cost and labor-intensive nature of in vitro and in vivo experiments have highlighted the importance of in silico-based DTI prediction approaches.…

Quantitative Methods · Quantitative Biology 2019-09-11 Ingoo Lee , Jongsoo Keum , Hojung Nam

Accurate prediction of RNA three-dimensional (3D) structure remains an unsolved challenge. Determining RNA 3D structures is crucial for understanding their functions and informing RNA-targeting drug development and synthetic biology design.…

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

Deep learning has emerged as a compelling solution to many NLP tasks with remarkable performances. However, due to their opacity, such models are hard to interpret and trust. Recent work on explaining deep models has introduced approaches…

Computation and Language · Computer Science 2019-05-21 Reza Ghaeini , Xiaoli Z. Fern , Hamed Shahbazi , Prasad Tadepalli

Interference Management is a vast topic present in many disciplines. The majority of wireless standards suffer the drawback of interference intrusion and the network efficiency drop due to that. Traditionally, interference management has…

Signal Processing · Electrical Eng. & Systems 2019-06-10 Pol Henarejos , Miguel Ángel Vázquez , Ana Isabel Pérez-Neira

Semantic communications could improve the transmission efficiency significantly by exploring the semantic information. In this paper, we make an effort to recover the transmitted speech signals in the semantic communication systems, which…

Signal Processing · Electrical Eng. & Systems 2021-09-09 Zhenzi Weng , Zhijin Qin

Automated ranking of pre-trained Deep Neural Networks (DNNs) reduces the required time for selecting optimal pre-trained DNN and boost the classification performance in transfer learning. In this paper, we introduce a novel algorithm to…

Machine Learning · Computer Science 2020-12-29 Mostafa Kalhor , Ahmad Kalhor , Mehdi Rahmani

In speech enhancement, complex neural network has shown promising performance due to their effectiveness in processing complex-valued spectrum. Most of the recent speech enhancement approaches mainly focus on wide-band signal with a…

Audio and Speech Processing · Electrical Eng. & Systems 2021-11-17 Shubo Lv , Yihui Fu , Mengtao Xing , Jiayao Sun , Lei Xie , Jun Huang , Yannan Wang , Tao Yu

Surgical training in medical school residency programs has followed the apprenticeship model. The learning and assessment process is inherently subjective and time-consuming. Thus, there is a need for objective methods to assess surgical…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Erim Yanik , Xavier Intes , Uwe Kruger , Pingkun Yan , David Miller , Brian Van Voorst , Basiel Makled , Jack Norfleet , Suvranu De

Despite their unprecedented performance in various domains, utilization of Deep Neural Networks (DNNs) in safety-critical environments is severely limited in the presence of even small adversarial perturbations. The present work develops a…

Machine Learning · Computer Science 2020-10-19 Fatemeh Sheikholeslami , Swayambhoo Jain , Georgios B. Giannakis

We systematically evaluate a Deep Learning (DL) method in a 3D medical image segmentation task. Our segmentation method is integrated into the radiosurgery treatment process and directly impacts the clinical workflow. With our method, we…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Boris Shirokikh , Alexandra Dalechina , Alexey Shevtsov , Egor Krivov , Valery Kostjuchenko , Amayak Durgaryan , Mikhail Galkin , Andrey Golanov , Mikhail Belyaev

In this study, we propose a machine learning-based method for noise reduction and disease-causing gene feature extraction in gene sequencing DeepSeqDenoise algorithm combines CNN and RNN to effectively remove the sequencing noise, and…

Machine Learning · Computer Science 2025-05-27 Weichen Si , Yihao Ou , Zhen Tian

Adversarial examples are known to mislead deep learning models to incorrectly classify them, even in domains where such models achieve state-of-the-art performance. Until recently, research on both attack and defense methods focused on…

Cryptography and Security · Computer Science 2019-11-22 Ishai Rosenberg , Asaf Shabtai , Yuval Elovici , Lior Rokach

The success of modern farming and plant breeding relies on accurate and efficient collection of data. For a commercial organization that manages large amounts of crops, collecting accurate and consistent data is a bottleneck. Due to limited…

Computer Vision and Pattern Recognition · Computer Science 2021-02-26 Saeed Khaki , Hieu Pham , Ye Han , Andy Kuhl , Wade Kent , Lizhi Wang

In recent years, deep learning methods applying unsupervised learning to train deep layers of neural networks have achieved remarkable results in numerous fields. In the past, many genetic algorithms based methods have been successfully…

Neural and Evolutionary Computing · Computer Science 2017-11-22 Eli David , Iddo Greental

Recent work has shown the promise of applying deep learning to enhance software processing of radio frequency (RF) signals. In parallel, hardware developments with quantum RF sensors based on Rydberg atoms are breaking longstanding barriers…

Quantum Physics · Physics 2025-04-24 Pranav Gokhale , Caitlin Carnahan , William Clark , Teague Tomesh , Frederic T. Chong

This paper proposes a sparse Bayesian treatment of deep neural networks (DNNs) for system identification. Although DNNs show impressive approximation ability in various fields, several challenges still exist for system identification…

Systems and Control · Electrical Eng. & Systems 2022-06-02 Hongpeng Zhou , Chahine Ibrahim , Wei Xing Zheng , Wei Pan

In recent years, continuous latent space (CLS) and discrete latent space (DLS) deep learning models have been proposed for medical image analysis for improved performance. However, these models encounter distinct challenges. CLS models…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Vandan Gorade , Sparsh Mittal , Debesh Jha , Ulas Bagci

The success of deep learning has been witnessed as a promising technique for computer-aided biomedical image analysis, due to end-to-end learning framework and availability of large-scale labelled samples. However, in many cases of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-02 Pengyi Zhang , Yunxin Zhong , Yulin Deng , Xiaoying Tang , Xiaoqiong Li
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