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Four-dimensional Flow MRI enables non-invasive, time-resolved imaging of blood flow in three spatial dimensions, offering valuable insights into complex hemodynamics. However, its clinical utility is limited by low spatial resolution and…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Aurélien de Turenne , Rémi Cart-Lamy , Denis Kouamé

4D-flow magnetic resonance imaging (MRI) is an emerging imaging technique where spatiotemporal 3D blood velocity can be captured with full volumetric coverage in a single non-invasive examination. This enables qualitative and quantitative…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Edward Ferdian , Avan Suinesiaputra , David Dubowitz , Debbie Zhao , Alan Wang , Brett Cowan , Alistair Young

Phase-contrast magnetic resonance imaging (MRI) provides time-resolved quantification of blood flow dynamics that can aid clinical diagnosis. Long in vivo scan times due to repeated three-dimensional (3D) volume sampling over cardiac phases…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Valery Vishnevskiy , Jonas Walheim , Sebastian Kozerke

Novel Magnetic Resonance (MR) imaging modalities can quantify hemodynamics but require long acquisition times, precluding its widespread use for early diagnosis of cardiovascular disease. To reduce the acquisition times, reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Lauren Partin , Daniele E. Schiavazzi , Carlos A. Sing Long

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive technique for volumetric, time-resolved blood flow quantification. However, apparent trade-offs between acquisition time, image noise, and resolution limit clinical…

Reconstructing high-quality magnetic resonance images (MRI) from undersampled raw data is of great interest from both technical and clinical point of views. To this date, however, it is still a mathematically and computationally challenging…

Numerical Analysis · Mathematics 2021-09-01 T. Schmoderer , A. I Aviles-Rivero , V. Corona , N. Debroux , C-B. Schönlieb

High-fidelity patient-specific modeling of cardiovascular flows and hemodynamics is challenging. Direct blood flow measurement inside the body with in-vivo measurement modalities such as 4D flow magnetic resonance imaging (4D flow MRI)…

Fluid Dynamics · Physics 2021-06-11 Milad Habibi , Roshan M. D'Souza , Scott T. M. Dawson , Amirhossein Arzani

Background: Image reconstruction from highly undersampled 4D flow MRI data can be very time consuming and may result in significant underestimation of velocities depending on regularization, thereby limiting the applicability of the method.…

Medical Physics · Physics 2025-04-01 Luuk Jacobs , Marco Piccirelli , Valery Vishnevskiy , Sebastian Kozerke

Reconstructing high-quality images from substantially undersampled k-space data for accelerated MRI presents a challenging ill-posed inverse problem. While supervised deep learning has revolutionized this field, it relies heavily on large…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Xinzhe Luo , Yingzhen Li , Chen Qin

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

As the original velocity field obtained from four-dimensional (4D) flow magnetic resonance imaging (MRI) contains considerable amount of noises and errors, the available Divergence-free smoothing (DFS) method can be used to process the 4D…

Computational Engineering, Finance, and Science · Computer Science 2019-12-10 Qi Gao , Xingli Liu , Hongping Wang , Fei Li , Peng Wu , Zhaozhuo Niu , Mansu Jin , RunJie Wei

4D flow magnetic resonance imaging (MRI) is a reliable, non-invasive approach for estimating blood flow velocities, vital for cardiovascular diagnostics. Unlike conventional MRI focused on anatomical structures, 4D flow MRI requires high…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Sun Jo , Seok Young Hong , JinHyun Kim , Seungmin Kang , Ahjin Choi , Don-Gwan An , Simon Song , Je Hyeong Hong

Purpose: 3D Time-of-flight (TOF) MR Angiography (MRA) can accurately visualize the intracranial vasculature, but is limited by long acquisition times. Compressed sensing (CS) reconstruction can be used to substantially accelerate…

Medical Physics · Physics 2021-04-12 Matthijs H. S. de Buck , Peter Jezzard , Aaron T. Hess

4D flow MRI is a non-invasive imaging method that can measure blood flow velocities over time. However, the velocity fields detected by this technique have limitations due to low resolution and measurement noise. Coordinate-based neural…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Simone Saitta , Marcello Carioni , Subhadip Mukherjee , Carola-Bibiane Schönlieb , Alberto Redaelli

4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive measurement technique capable of quantifying blood flow across the cardiovascular system. While practical use is limited by spatial resolution and image noise, incorporation…

Several cardiovascular diseases are caused from localised abnormal blood flow such as in the case of stenosis or aneurysms. Prevailing theories propose that the development is caused by abnormal wall-shear stress in focused areas.…

Optimization and Control · Mathematics 2016-07-12 S. W. Funke , M. Nordaas , Øyvind Evju , M. S. Alnæs , K. -A. Mardal

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Reconstructing high-quality images from undersampled dynamic MRI data is a challenging task and important for the success of this imaging modality. To remedy the naturally occurring artifacts due to measurement undersampling, one can…

Optimization and Control · Mathematics 2025-04-29 Matthias J. Ehrhardt , Marco Mauritz

We introduce SMURF, a scalable and unsupervised machine learning method for simultaneously segmenting vascular geometries and reconstructing velocity fields from 4D flow MRI data. SMURF models geometry and velocity fields using multilayer…

Medical Physics · Physics 2026-01-27 Atharva Hans , Abhishek Singh , Pavlos Vlachos , Ilias Bilionis
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