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Retinal image analysis is crucial for diagnosing and treating eye diseases, yet generating accurate medical reports from images remains challenging due to variability in image quality and pathology, especially with limited labeled data.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Teja Krishna Cherukuri , Nagur Shareef Shaik , Jyostna Devi Bodapati , Dong Hye Ye

Multimodal large language models (MLLMs) have emerged as a prominent area of interest within the research community, given their proficiency in handling and reasoning with non-textual data, including images and videos. This study seeks to…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Zhenhua Xu , Yujia Zhang , Enze Xie , Zhen Zhao , Yong Guo , Kwan-Yee. K. Wong , Zhenguo Li , Hengshuang Zhao

Vision-Language Models (VLMs) are becoming increasingly popular in the medical domain, bridging the gap between medical images and clinical language. Existing VLMs demonstrate an impressive ability to comprehend medical images and text…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Bidur Khanal , Sandesh Pokhrel , Sanjay Bhandari , Ramesh Rana , Nikesh Shrestha , Ram Bahadur Gurung , Cristian Linte , Angus Watson , Yash Raj Shrestha , Binod Bhattarai

This survey and application guide to multimodal large language models(MLLMs) explores the rapidly developing field of MLLMs, examining their architectures, applications, and impact on AI and Generative Models. Starting with foundational…

Artificial Intelligence · Computer Science 2025-12-02 Chia Xin Liang , Pu Tian , Caitlyn Heqi Yin , Yao Yua , Wei An-Hou , Li Ming , Xinyuan Song , Tianyang Wang , Ziqian Bi , Ming Liu

The development of large vision-language models (LVLMs) offers the potential to address challenges faced by traditional multimodal recommendations thanks to their proficient understanding of static images and textual dynamics. However, the…

Artificial Intelligence · Computer Science 2024-02-14 Yuqing Liu , Yu Wang , Lichao Sun , Philip S. Yu

Multimodal large language models (MLLMs) represent an evolutionary expansion in the capabilities of traditional large language models, enabling them to tackle challenges that surpass the scope of purely text-based applications. It leverages…

Computation and Language · Computer Science 2025-01-17 Jinlong He , Pengfei Li , Gang Liu , Genrong He , Zhaolin Chen , Shenjun Zhong

The success of large language models (LLMs) has inspired an emerging research field of multimodal learning. However, a grand challenge of exploiting LLMs for multimodal learning is the size of pre-trained LLMs which are always with billions…

Computation and Language · Computer Science 2024-04-08 Zhengqing Yuan , Yunhong He , Kun Wang , Yanfang Ye , Lichao Sun

We explore Multimodal Large Language Models (MLLMs), which integrate LLMs like GPT-4 to handle multimodal data, including text, images, audio, and more. MLLMs demonstrate capabilities such as generating image captions and answering…

Computation and Language · Computer Science 2025-01-09 Shezheng Song , Xiaopeng Li , Shasha Li , Shan Zhao , Jie Yu , Jun Ma , Xiaoguang Mao , Weimin Zhang

Several medical Multimodal Large Languange Models (MLLMs) have been developed to address tasks involving visual images with textual instructions across various medical modalities, achieving impressive results. Most current medical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Haonan Wang , Honglong Yang , Jiaji Mao , Zehong Yang , Jun Shen , Xiaomeng Li

Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

Multimodal large language models (MLLMs) enhance the capabilities of standard large language models by integrating and processing data from multiple modalities, including text, vision, audio, video, and 3D environments. Data plays a pivotal…

Artificial Intelligence · Computer Science 2024-07-19 Tianyi Bai , Hao Liang , Binwang Wan , Yanran Xu , Xi Li , Shiyu Li , Ling Yang , Bozhou Li , Yifan Wang , Bin Cui , Ping Huang , Jiulong Shan , Conghui He , Binhang Yuan , Wentao Zhang

Large language models (LLMs) can handle a wide variety of general tasks with simple prompts, without the need for task-specific training. Multimodal Large Language Models (MLLMs), built upon LLMs, have demonstrated impressive potential in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Tao Yu , Yi-Fan Zhang , Chaoyou Fu , Junkang Wu , Jinda Lu , Kun Wang , Xingyu Lu , Yunhang Shen , Guibin Zhang , Dingjie Song , Yibo Yan , Tianlong Xu , Qingsong Wen , Zhang Zhang , Yan Huang , Liang Wang , Tieniu Tan

Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits and heterogeneity of multi-sources genomics data pose…

Computation and Language · Computer Science 2025-11-25 Yanjun Lyu , Zihao Wu , Lu Zhang , Jing Zhang , Yiwei Li , Wei Ruan , Zhengliang Liu , Zeyu Zhang , Xiang Li , Rongjie Liu , Chao Huang , Wentao Li , Tianming Liu , Dajiang Zhu

Multimodal Large Language Models (MLLMs), such as GPT4o, have shown strong capabilities in visual reasoning and explanation generation. However, despite these strengths, they face significant challenges in the increasingly critical task of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Fanrui Zhang , Jiawei Liu , Jiaying Zhu , Esther Sun , Dong Li , Qiang Zhang , Zheng-Jun Zha

The global demand for radiologists is increasing rapidly due to a growing reliance on medical imaging services, while the supply of radiologists is not keeping pace. Advances in computer vision and image processing technologies present…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Shehroz S. Khan , Petar Przulj , Ahmed Ashraf , Ali Abedi

Recent advancements in Multimodal Large Language Models (MLLMs) have greatly improved their abilities in image understanding. However, these models often struggle with grasping pixel-level semantic details, e.g., the keypoints of an object.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Jie Yang , Wang Zeng , Sheng Jin , Lumin Xu , Wentao Liu , Chen Qian , Ruimao Zhang

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Multimodal Large Language Models (MLLMs) mimic human perception and reasoning system by integrating powerful Large Language Models (LLMs) with various modality encoders (e.g., vision, audio), positioning LLMs as the "brain" and various…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Jiaxing Huang , Jingyi Zhang

Multimodal Large Language Models (MLLMs) have demonstrated remarkable effectiveness in various general-domain scenarios, such as visual question answering and image captioning. Recently, researchers have increasingly focused on empowering…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yan Shu , Chi Liu , Robin Chen , Derek Li , Bryan Dai

Multimodal large language models (MLLMs) are changing how Blind and Low Vision (BLV) people access visual information. Unlike traditional visual interpretation tools that only provide descriptions, MLLM-enabled applications offer…

Human-Computer Interaction · Computer Science 2026-02-20 Ricardo E. Gonzalez Penuela , Crescentia Jung , Sharon Y Lin , Ruiying Hu , Shiri Azenkot