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We present InfoVAE-Med3D, a latent-representation learning approach for 3D brain MRI that targets interpretable biomarkers of cognitive decline. Standard statistical models and shallow machine learning often lack power, while most deep…

Modern Latent Diffusion Models (LDMs) typically operate in low-level Variational Autoencoder (VAE) latent spaces that are primarily optimized for pixel-level reconstruction. To unify vision generation and understanding, a burgeoning trend…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Shilong Zhang , He Zhang , Zhifei Zhang , Chongjian Ge , Shuchen Xue , Shaoteng Liu , Mengwei Ren , Soo Ye Kim , Yuqian Zhou , Qing Liu , Daniil Pakhomov , Kai Zhang , Zhe Lin , Ping Luo

Generative artificial intelligence (AI) has been playing an important role in various domains. Leveraging its high capability to generate high-fidelity and diverse synthetic data, generative AI is widely applied in diagnostic tasks, such as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Yifan Jiang , Ahmad Shariftabrizi , Venkata SK. Manem

Recent advances in generative models have yielded impressive progress on motion in-betweening, allowing for more complex, varied, and realistic motion transitions. However, recent methods still exhibit noticeable limitations in preserving…

Graphics · Computer Science 2026-05-14 Shiyu Fan , Paul Henderson , Edmond S. L. Ho

In this paper, we present an approach for combining non-rigid structure-from-motion (NRSfM) with deep generative models,and propose an efficient framework for discovering trajectories in the latent space of 2D GANs corresponding to changes…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 René Haas , Stella Graßhof , Sami S. Brandt

The recovery of high-quality images from images corrupted by lens flare presents a significant challenge in low-level vision. Contemporary deep learning methods frequently entail training a lens flare removing model from scratch. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Tianwen Zhou , Qihao Duan , Zitong Yu

The field of neural rendering has witnessed significant progress with advancements in generative models and differentiable rendering techniques. Though 2D diffusion has achieved success, a unified 3D diffusion pipeline remains unsettled.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Yushi Lan , Fangzhou Hong , Shangchen Zhou , Shuai Yang , Xuyi Meng , Yongwei Chen , Zhaoyang Lyu , Bo Dai , Xingang Pan , Chen Change Loy

We present a longitudinal MR simulation framework which simulates the future neurodegenerative progression by outputting the predicted follow-up MR image and the voxel-based morphometry (VBM) map. This framework expects the patients to have…

Computer Vision and Pattern Recognition · Computer Science 2015-08-25 Siqi Liu , Sidong Liu , Sonia Pujol , Ron Kikinis , Dagan Feng , Michael Fulham , Weidong Cai

In this work, we present a new method for 3D face reconstruction from sparse-view RGB images. Unlike previous methods which are built upon 3D morphable models (3DMMs) with limited details, we leverage an implicit representation to encode…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Moran Li , Haibin Huang , Yi Zheng , Mengtian Li , Nong Sang , Chongyang Ma

Latent diffusion models have emerged as powerful generative models in medical imaging, enabling the synthesis of high quality brain magnetic resonance imaging scans. In particular, predicting the evolution of a patients brain can aid in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Duy-Phuong Dao , Muhammad Taqiyuddin , Jahae Kim , Sang-Heon Lee , Hye-Won Jung , Jaehoo Choi , Hyung-Jeong Yang

Synthetic neuroimaging data can mitigate critical limitations of real-world datasets, including the scarcity of rare phenotypes, domain shifts across scanners, and insufficient longitudinal coverage. However, existing generative models…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Fabian Bongratz , Yitong Li , Sama Elbaroudy , Christian Wachinger

The generation of three-dimensional (3D) medical images has great application potential since it takes into account the 3D anatomical structure. Two problems prevent effective training of a 3D medical generative model: (1) 3D medical images…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Yanbin Liu , Girish Dwivedi , Farid Boussaid , Frank Sanfilippo , Makoto Yamada , Mohammed Bennamoun

Deformable shape representations, parameterized by deformations relative to a given template, have proven effective for improved image analysis tasks. However, their broader applicability is hindered by two major challenges. First, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Tonmoy Hossain , Miaomiao Zhang

Deformable registration is one of the most challenging task in the field of medical image analysis, especially for the alignment between different sequences and modalities. In this paper, a non-rigid registration method is proposed for 3D…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Xiaoyue Zhang , Weijian Jian , Yu Chen , Shihting Yang

Generative modeling frameworks have emerged as an effective approach to capture high-dimensional image distributions from large datasets without requiring domain-specific knowledge, a capability essential for longitudinal disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Ayantika Das , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

Understanding how the brain encodes visual information is a central challenge in neuroscience and machine learning. A promising approach is to reconstruct visual stimuli, essentially images, from functional Magnetic Resonance Imaging (fMRI)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zheng Huang , Enpei Zhang , Weikang Qiu , Yinghao Cai , Carl Yang , Elynn Chen , Xiang Zhang , Rex Ying , Dawei Zhou , Yujun Yan

We present Surf-D, a novel method for generating high-quality 3D shapes as Surfaces with arbitrary topologies using Diffusion models. Previous methods explored shape generation with different representations and they suffer from limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Zhengming Yu , Zhiyang Dou , Xiaoxiao Long , Cheng Lin , Zekun Li , Yuan Liu , Norman Müller , Taku Komura , Marc Habermann , Christian Theobalt , Xin Li , Wenping Wang

Longitudinal brain MRI is essential for lifespan study, yet high attrition rates often lead to missing data, complicating analysis. Deep generative models have been explored, but most rely solely on image intensity, leading to two key…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Tianli Tao , Ziyang Wang , Delong Yang , Han Zhang , Le Zhang

The ability to generate 3D multiphase microstructures on-demand with targeted attributes can greatly accelerate the design of advanced materials. Here, we present a conditional latent diffusion model (LDM) framework that rapidly synthesizes…

Body composition analysis provides valuable insights into aging, disease progression, and overall health conditions. Due to concerns of radiation exposure, two-dimensional (2D) single-slice computed tomography (CT) imaging has been used…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Lianrui Zuo , Xin Yu , Dingjie Su , Kaiwen Xu , Aravind R. Krishnan , Yihao Liu , Shunxing Bao , Fabien Maldonado , Luigi Ferrucci , Bennett A. Landman