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In this work, we address the problem of grounding abnormalities in medical images, where the goal is to localize clinical findings based on textual descriptions. While generalist Vision-Language Models (VLMs) excel in natural grounding…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Jun Li , Che Liu , Wenjia Bai , Mingxuan Liu , Rossella Arcucci , Cosmin I. Bercea , Julia A. Schnabel

Existing Medical Large Vision-Language Models (Med-LVLMs), encapsulating extensive medical knowledge, demonstrate excellent capabilities in understanding medical images. However, there remain challenges in visual localization in medical…

Computation and Language · Computer Science 2025-06-03 Yucheng Zhou , Lingran Song , Jianbing Shen

Recent advancements in Vision Language Models (VLMs) have demonstrated remarkable promise in generating visually grounded responses. However, their application in the medical domain is hindered by unique challenges. For instance, most VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Lingxiao Luo , Bingda Tang , Xuanzhong Chen , Rong Han , Ting Chen

Large Vision-Language Models (LVLMs) offer remarkable benefits for a variety of vision-language tasks. However, a challenge hindering their application in real-world scenarios, particularly regarding safety, robustness, and reliability, is…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jiaying Lu , Jinmeng Rao , Kezhen Chen , Xiaoyuan Guo , Yawen Zhang , Baochen Sun , Carl Yang , Jie Yang

While traditional computer vision models have historically struggled to generalize to endoscopic domains, the emergence of foundation models has shown promising cross-domain performance. In this work, we present the first large-scale study…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Leon Mayer , Tim Rädsch , Dominik Michael , Lucas Luttner , Amine Yamlahi , Evangelia Christodoulou , Patrick Godau , Marcel Knopp , Annika Reinke , Fiona Kolbinger , Lena Maier-Hein

Generalist multimodal large language models (MLLMs) have achieved impressive performance across a wide range of vision-language tasks. However, their performance on medical tasks, particularly in zero-shot settings where generalization is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Guimeng Liu , Tianze Yu , Somayeh Ebrahimkhani , Lin Zhi Zheng Shawn , Kok Pin Ng , Ngai-Man Cheung

Modern Vision-Language Models (VLMs) exhibit unprecedented capabilities in cross-modal semantic understanding between visual and textual modalities. Given the intrinsic need for multi-modal integration in clinical applications, VLMs have…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Haoneng Lin , Cheng Xu , Jing Qin

Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

Large vision-and-language models (VLMs) trained to match images with text on large-scale datasets of image-text pairs have shown impressive generalization ability on several vision and language tasks. Several recent works, however, showed…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Navid Rajabi , Jana Kosecka

A visual-language model (VLM) pre-trained on natural images and text pairs poses a significant barrier when applied to medical contexts due to domain shift. Yet, adapting or fine-tuning these VLMs for medical use presents considerable…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Aisha Urooj Khan , John Garrett , Tyler Bradshaw , Lonie Salkowski , Jiwoong Jason Jeong , Amara Tariq , Imon Banerjee

Despite significant progress in multimodal language models (LMs), it remains unclear whether visual grounding enhances their understanding of embodied knowledge compared to text-only models. To address this question, we propose a novel…

Computation and Language · Computer Science 2025-10-21 Zhihui Yang , Yupei Wang , Kaijie Mo , Zhe Zhao , Renfen Hu

Vision-language models (VLMs) have made substantial progress across a wide range of visual question answering benchmarks, spanning visual reasoning, document understanding, and multimodal dialogue. These improvements are evident in a wide…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Dhruba Ghosh , Yuhui Zhang , Ludwig Schmidt

Large vision-language models (LVLMs) are markedly proficient in deriving visual representations guided by natural language. Recent explorations have utilized LVLMs to tackle zero-shot visual anomaly detection (VAD) challenges by pairing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Jiaqi Zhu , Shaofeng Cai , Fang Deng , Beng Chin Ooi , Junran Wu

Vision language models (VLMs) have shown significant promise in visual grounding for images as well as videos. In medical imaging research, VLMs represent a bridge between object detection and segmentation, and report understanding and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Andrew Seohwan Yu , Mohsen Hariri , Kunio Nakamura , Mingrui Yang , Xiaojuan Li , Vipin Chaudhary

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

Spatio-physical reasoning, a foundation capability for understanding the real physics world, is a critical step towards building robust world models. While recent vision language models (VLMs) have shown remarkable progress in specialized…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Tiancheng Han , Yunfei Gao , Yong Li , Wuzhou Yu , Qiaosheng Zhang , Wenqi Shao

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

Multimodal Large Language Models (MLLMs) inherit the superior text understanding capabilities of LLMs and extend these capabilities to multimodal scenarios. These models achieve excellent results in the general domain of multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinlong He , Pengfei Li , Gang Liu , Shenjun Zhong

Modern neural language models (LMs) are powerful tools for modeling human sentence production and comprehension, and their internal representations are remarkably well-aligned with representations of language in the human brain. But to…

Computation and Language · Computer Science 2024-03-27 Chengxu Zhuang , Evelina Fedorenko , Jacob Andreas

This paper explores training medical vision-language models (VLMs) -- where the visual and language inputs are embedded into a common space -- with a particular focus on scenarios where training data is limited, as is often the case in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rhydian Windsor , Amir Jamaludin , Timor Kadir , Andrew Zisserman
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