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ChatGPT has drawn considerable attention from both the general public and domain experts with its remarkable text generation capabilities. This has subsequently led to the emergence of diverse applications in the field of biomedicine and…
The performance of deep learning-based natural language processing systems is based on large amounts of labeled training data which, in the clinical domain, are not easily available or affordable. Weak supervision and in-context learning…
Improving performance on complex tasks and enabling interpretable decision making in large language models (LLMs), especially for clinical applications, requires effective reasoning. Yet this remains challenging without supervised…
Tumor documentation in Germany is largely done manually, requiring reading patient records and entering data into structured databases. Large language models (LLMs) could potentially enhance this process by improving efficiency and…
State-of-the-art supervised NLP models achieve high accuracy but are also susceptible to failures on inputs from low-data regimes, such as domains that are not represented in training data. As an approximation to collecting ground-truth…
Large Language Models (LLMs) recently achieved great success in medical text summarization by simply using in-context learning. However, these recent efforts do not perform fine-grained evaluations under difficult settings where LLMs might…
Large Language Models (LLMs) have demonstrated proficiency in a wide array of natural language processing tasks. However, its effectiveness over discourse-level event relation extraction (ERE) tasks remains unexplored. In this paper, we…
Detecting jailbreak attempts in clinical training large language models (LLMs) requires accurate modeling of linguistic deviations that signal unsafe or off-task user behavior. Prior work on the 2-Sigma clinical simulation platform showed…
Large language models (LLMs) with billions of parameters and pretrained on massive amounts of data are now capable of near or better than state-of-the-art performance in a variety of downstream natural language processing tasks. Neural…
Understanding the intricate interplay among sequence, structure, and function remains a fundamental challenge in proteomics. The sequence-structure-function paradigm posits that biological roles are governed by the tertiary geometric…
Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…
Systematic reviews and meta-analyses rely on converting narrative articles into structured, numerically grounded study records. Despite rapid advances in large language models (LLMs), it remains unclear whether they can meet the structural…
The escalating volume of collected healthcare textual data presents a unique challenge for automated Multi-Label Text Classification (MLTC), which is primarily due to the scarcity of annotated texts for training and their nuanced nature.…
The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…
Frontier large language models (LLMs) are developed by researchers and practitioners with skewed cultural backgrounds and on datasets with skewed sources. However, LLMs' (lack of) multicultural knowledge cannot be effectively assessed with…
While large language models (LLMs) demonstrate reasonable zero-shot capability across many downstream tasks, fine-tuning is a common practice to improve their performance. However, a task's data efficiency--i.e., the number of fine-tuning…
Large Language Models (LLMs) have become extremely potent instruments with exceptional capacities for comprehending and producing human-like text in a wide range of applications. However, the increasing size and complexity of LLMs present…
Although large language models (LLMs) are increasingly used as annotators at scale, they are typically treated as a pragmatic fallback rather than a faithful estimator of human perspectives. This work challenges that presumption. By framing…
When complex SQL queries suffer slow executions despite query optimization, DBAs typically invoke automated query rewriting tools to recommend ``lean'' equivalents that are conducive to faster execution. The rewritings are usually achieved…
Tools to explore scientific literature are essential for scientists, especially in biomedicine, where about a million new papers are published every year. Many such tools provide users the ability to search for specific entities (e.g.…