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We propose a novel approach to generate samples from the conditional distribution of patient-specific cardiovascular models given a clinically aquired image volume. A convolutional neural network architecture with dropout layers is first…

Quantitative Methods · Quantitative Biology 2021-09-01 Gabriel Maher , Casey Fleeter , Daniele Schiavazzi , Alison Marsden

The way organs are positioned and moved in the workplace can cause pain and physical harm. Therefore, ergonomists use ergonomic risk assessments based on visual observation of the workplace, or review pictures and videos taken in the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Amin Ahmadi Kasani , Hedieh Sajedi

As the number of patients with heart failure increases, machine learning (ML) has garnered attention in cardiomyopathy diagnosis, driven by the shortage of pathologists. However, endomyocardial biopsy specimens are often small sample size…

Machine Learning · Computer Science 2025-10-23 Masaya Mori , Yuto Omae , Yutaka Koyama , Kazuyuki Hara , Jun Toyotani , Yasuo Okumura , Hiroyuki Hao

Neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), cause progressive muscular degeneration and loss of motor function for 1 in 6,000 children. Traditional upper limb motor function…

Coronary anatomy governs local haemodynamics associated with atherosclerotic development, progression and ultimately adverse clinical outcomes. However, lack of large sample size studies and methods to link adverse haemodynamics to…

Medical Physics · Physics 2024-01-24 R. Gharleghi , M. Zhang , C. Shen , M. Webster , C. Ellis , S. Beier

Total endovascular repair of the aortic arch represents a promising option for patients ineligible to open surgery. Custom-made design of stent-grafts (SG), such as the Terumo Aortic RelayBranch device (DB), requires complex preoperative…

Medical Physics · Physics 2019-02-11 L. Derycke , D. Perrin , F. Cochennec , J. -N. Albertini , S. Avril

Leveraging big data for patient care is promising in many medical fields such as cardiovascular health. For example, hemodynamic biomarkers like wall shear stress could be assessed from patient-specific medical images via machine learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Julian Suk , Jolanda J. Wentzel , Patryk Rygiel , Joost Daemen , Daniel Rueckert , Jelmer M. Wolterink

In this paper, we study the problem of shape-programming of incompressible hyperelastic shells through differential growth. The aim of the current work is to determine the growth tensor (or growth functions) that can produce the deformation…

Numerical Analysis · Mathematics 2022-10-13 Zhanfeng Li , Jiong Wang , Mokarram Hossain , Chennakesava Kadapa

Objective: Computer-aided disease diagnosis and prognosis based on medical images is a rapidly emerging field. Many Convolutional Neural Network (CNN) architectures have been developed by researchers for disease classification and…

Image and Video Processing · Electrical Eng. & Systems 2023-12-27 Md. Iqbal Hossain , Mohammad Zunaed , Md. Kawsar Ahmed , S. M. Jawwad Hossain , Anwarul Hasan , Taufiq Hasan

Statistical Shape Modeling (SSM) is a quantitative method for analyzing morphological variations in anatomical structures. These analyses often necessitate building models on targeted anatomical regions of interest to focus on specific…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Hong Xu , Alan Morris , Shireen Y. Elhabian

Endovascular treatment of cerebral aneurysms aims to achieve functional occlusion and isolation of the aneurysm sac from bloodflow. In clinical practice, treatment success is assessed primarily through digital subtraction angiography (DSA),…

Computational Engineering, Finance, and Science · Computer Science 2026-05-06 Fabian Holzberger , Struan Hume , Markus Muhr , Malebogo Ngoepe , Barbara Wohlmuth

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Purpose: Convolutional neural networks (CNNs) are promising in predicting treatment outcome for pediatric craniopharyngioma while the decision mechanisms are difficult to interpret. We compared the activation maps of CNN with hand crafted…

Medical Physics · Physics 2025-09-26 Wenjun Yang , Chuang Wang , Tina Davis , Jinsoo Uh , Chia-Ho Hua , Thomas E. Merchant

In this paper, we propose crossing statistics and its generalization, as a new framework to characterize the anisotropy in a 2D field, e.g. height on a surface, extendable to higher dimensions. By measuring $\nu^+$, the number of…

Computational Physics · Physics 2018-10-12 M. Ghasemi Nezhadhaghighi , S. M. S. Movahed , T. Yasseri , S. M. Vaez Allaei

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

In this paper, we propose a method for characterizing 3D shapes from point clouds and we show a direct application on a study of organ temporal deformations. As an example, we characterize the behavior of a bladder during a forced…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Karim Makki , Amine Bohi , Augustin C. Ogier , Marc-Emmanuel Bellemare

Conventional manual surveys of rock mass fractures usually require large amounts of time and labor; yet, they provide a relatively small set of data that cannot be considered representative of the study region. Terrestrial laser scanners…

Computer Vision and Pattern Recognition · Computer Science 2017-07-19 Xin Wang , Lejun Zou , Xiaohua Shen , Yupeng Ren , Yi Qin

Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Jadie Adams , Shireen Elhabian

From a fresh data science perspective, this thesis discusses the prediction of coronary artery disease based on genetic variations at the DNA base pair level, called Single-Nucleotide Polymorphisms (SNPs), collected from the Ontario Heart…

Machine Learning · Computer Science 2014-02-04 Hubert Haoyang Duan

Statistical shape modeling is an essential tool for the quantitative analysis of anatomical populations. Point distribution models (PDMs) represent the anatomical surface via a dense set of correspondences, an intuitive and easy-to-use…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Wenzheng Tao , Riddhish Bhalodia , Shireen Elhabian