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The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Jie Liu , Yixiao Zhang , Kang Wang , Mehmet Can Yavuz , Xiaoxi Chen , Yixuan Yuan , Haoliang Li , Yang Yang , Alan Yuille , Yucheng Tang , Zongwei Zhou

Large-scale image data such as digital whole-slide histology images pose a challenging task at annotation software solutions. Today, a number of good solutions with varying scopes exist. For cell annotation, however, we find that many do…

Computer Vision and Pattern Recognition · Computer Science 2018-10-03 Marc Aubreville , Christof Bertram , Robert Klopfleisch , Andreas Maier

In recent years, a standard computational pathology workflow has emerged where whole slide images are cropped into tiles, these tiles are processed using a foundation model, and task-specific models are built using the resulting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Eric Zimmermann , Julian Viret , Michal Zelechowski , James Brian Hall , Neil Tenenholtz , Adam Casson , George Shaikovski , Eugene Vorontsov , Siqi Liu , Kristen A Severson

Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi

Iris recognition is widely recognized as one of the most accurate biometric modalities. However, its growing deployment in real-world applications raises significant concerns regarding its vulnerability to Presentation Attacks (PAs).…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Raghavendra Ramachandra , Sushma Venkatesh

Pathologists are facing an increasing workload due to a growing volume of cases and the need for more comprehensive diagnoses. Aiming to facilitate workload reduction and faster turnaround times, we developed an artificial intelligence (AI)…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Ruben T. Lucassen , Nikolas Stathonikos , Gerben E. Breimer , Mitko Veta , Willeke A. M. Blokx

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Semantic image segmentation is an important prerequisite for context-awareness and autonomous robotics in surgery. The state of the art has focused on conventional RGB video data acquired during minimally invasive surgery, but full-scene…

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Zhongying Deng , Cheng Tang , Ziyan Huang , Jiashi Lin , Ying Chen , Junzhi Ning , Chenglong Ma , Jiyao Liu , Wei Li , Yinghao Zhu , Shujian Gao , Yanyan Huang , Sibo Ju , Yanzhou Su , Pengcheng Chen , Wenhao Tang , Tianbin Li , Haoyu Wang , Yuanfeng Ji , Hui Sun , Shaobo Min , Liang Peng , Feilong Tang , Haochen Xue , Rulin Zhou , Chaoyang Zhang , Wenjie Li , Shaohao Rui , Weijie Ma , Xingyue Zhao , Yibin Wang , Kun Yuan , Zhaohui Lu , Shujun Wang , Jinjie Wei , Lihao Liu , Dingkang Yang , Lin Wang , Yulong Li , Haolin Yang , Yiqing Shen , Lequan Yu , Xiaowei Hu , Yun Gu , Yicheng Wu , Benyou Wang , Minghui Zhang , Angelica I. Aviles-Rivero , Qi Gao , Hongming Shan , Xiaoyu Ren , Fang Yan , Hongyu Zhou , Haodong Duan , Maosong Cao , Shanshan Wang , Bin Fu , Xiaomeng Li , Zhi Hou , Chunfeng Song , Lei Bai , Yuan Cheng , Yuandong Pu , Xiang Li , Wenhai Wang , Hao Chen , Jiaxin Zhuang , Songyang Zhang , Huiguang He , Mengzhang Li , Bohan Zhuang , Zhian Bai , Rongshan Yu , Liansheng Wang , Yukun Zhou , Xiaosong Wang , Xin Guo , Guanbin Li , Xiangru Lin , Dakai Jin , Mianxin Liu , Wenlong Zhang , Qi Qin , Conghui He , Yuqiang Li , Ye Luo , Nanqing Dong , Jie Xu , Wenqi Shao , Bo Zhang , Qiujuan Yan , Yihao Liu , Jun Ma , Zhi Lu , Yuewen Cao , Zongwei Zhou , Jianming Liang , Shixiang Tang , Qi Duan , Dongzhan Zhou , Chen Jiang , Yuyin Zhou , Yanwu Xu , Jiancheng Yang , Shaoting Zhang , Xiaohong Liu , Siqi Luo , Yi Xin , Chaoyu Liu , Haochen Wen , Xin Chen , Alejandro Lozano , Min Woo Sun , Yuhui Zhang , Yue Yao , Xiaoxiao Sun , Serena Yeung-Levy , Xia Li , Jing Ke , Chunhui Zhang , Zongyuan Ge , Ming Hu , Jin Ye , Zhifeng Li , Yirong Chen , Yu Qiao , Junjun He

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Transformers have become the architecture of choice for learning long-range dependencies, yet their adoption in hyperspectral imaging (HSI) is still emerging. We reviewed more than 300 papers published up to 2025 and present the first…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Guyang Zhang , Waleed Abdulla

The annotation of large scale histopathology image datasets remains a major bottleneck in developing robust deep learning models for clinically relevant tasks, such as mitotic figure classification. Folder-based annotation workflows are…

Pathology is the study of microscopic inspection of tissue, and a pathology diagnosis is often the medical gold standard to diagnose disease. Pathology images provide a unique challenge for computer-vision-based analysis: a single pathology…

Accurate detection of all pathological findings in 3D medical images remains a significant challenge, as supervised models are limited to detecting only the few pathology classes annotated in existing datasets. To address this, we frame…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Mikhail Goncharov , Eugenia Soboleva , Mariia Donskova , Daniil Ignatyev , Mikhail Belyaev , Ivan Oseledets , Marina Munkhoeva , Maxim Panov

Processing giga-pixel whole slide histopathology images (WSI) is a computationally expensive task. Multiple instance learning (MIL) has become the conventional approach to process WSIs, in which these images are split into smaller patches…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Ramin Nakhli , Puria Azadi Moghadam , Haoyang Mi , Hossein Farahani , Alexander Baras , Blake Gilks , Ali Bashashati

Gastrointestinal (GI) diseases represent a clinically significant burden, necessitating precise diagnostic approaches to optimize patient outcomes. Conventional histopathological diagnosis suffers from limited reproducibility and diagnostic…

Artificial Intelligence (AI) has demonstrated success in computational pathology (CPath) for disease detection, biomarker classification, and prognosis prediction. However, its potential to learn unintended demographic biases, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Shengjia Chen , Ruchika Verma , Kevin Clare , Jannes Jegminat , Eugenia Alleva , Kuan-lin Huang , Brandon Veremis , Thomas Fuchs , Gabriele Campanella

Weakly supervised whole slide image classification is a key task in computational pathology, which involves predicting a slide-level label from a set of image patches constituting the slide. Constructing models to solve this task involves…

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