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Graph neural networks are widely used to learn global representations of graphs, which are then used for regression or classification tasks. Typically, the graphs in such data sets are connected, i.e. each training sample consists of a…

Computational Engineering, Finance, and Science · Computer Science 2022-11-01 Chen Shao , Zhou Chen , Pascal Friederich

The first step to realize automatic experimental data analysis for fusion plasma experiments is fitting noisy data of temperature and density spatial profiles, which are obtained routinely. However, it has been difficult to construct…

Plasma Physics · Physics 2019-07-24 Keisuke Fujii , Chihiro Suzuki , Masahiro Hasuo

We propose a method for gene expression based analysis of cancer phenotypes incorporating network biology knowledge through unsupervised construction of computational graphs. The structural construction of the computational graphs is driven…

Molecular Networks · Quantitative Biology 2020-10-02 Paul Scherer , Maja Trȩbacz , Nikola Simidjievski , Zohreh Shams , Helena Andres Terre , Pietro Liò , Mateja Jamnik

Here, we demonstrate how machine learning enables the prediction of comonomers reactivity ratios based on the molecular structure of monomers. We combined multi-task learning, multi-inputs, and Graph Attention Network to build a model…

Machine Learning · Computer Science 2023-01-04 Tung Nguyen , Mona Bavarian

LAMMPS is a widely popular classical Molecular Dynamics package. It was designed for materials modeling but it is well prepared for simulations in Soft Matter. The use packages like LAMMPS has advantages and disadvantages. The main…

Soft Condensed Matter · Physics 2021-02-25 C. S. Dias

Predicting reactants from a specified core product stands as a fundamental challenge within organic synthesis, termed retrosynthesis prediction. Recently, semi-template-based methods and graph-edits-based methods have achieved good…

Quantitative Methods · Quantitative Biology 2024-02-13 Zixun Lan , Binjie Hong , Jiajun Zhu , Zuo Zeng , Zhenfu Liu , Limin Yu , Fei Ma

The research activity outlined in this PhD thesis is devoted to define a general approach, a concrete architecture and a prototype Process Management System (PMS) for the automated adaptation of dynamic processes at run-time, on the basis…

Artificial Intelligence · Computer Science 2018-10-16 Andrea Marrella

Accurately modeling chemical reactions at the atomistic level requires high-level electronic structure theory due to the presence of unpaired electrons and the need to properly describe bond breaking and making energetics. Commonly used…

Molecule representation learning (MRL) methods aim to embed molecules into a real vector space. However, existing SMILES-based (Simplified Molecular-Input Line-Entry System) or GNN-based (Graph Neural Networks) MRL methods either take…

Machine Learning · Computer Science 2021-09-23 Hongwei Wang , Weijiang Li , Xiaomeng Jin , Kyunghyun Cho , Heng Ji , Jiawei Han , Martin D. Burke

The core of molecular dynamics simulation fundamentally lies in the interatomic potential. Traditional empirical potentials lack accuracy, while first-principles methods are computationally prohibitive. Machine learning interatomic…

Machine Learning · Computer Science 2026-03-25 Shuyu Bi , Zhede Zhao , Qiangchao Sun , Tao Hu , Xionggang Lu , Hongwei Cheng

Molecular design requires systematic and broadly applicable methods to extract structure-property relationships. The focus of this study is on learning thermodynamic properties from molecular-liquid simulations. The methodology relies on an…

Materials Science · Physics 2023-07-04 Bernadette Mohr , Diego van der Mast , Tristan Bereau

This paper presents the first study on using large-scale pre-trained language models for automated generation of an event-level temporal graph for a document. Despite the huge success of neural pre-training methods in NLP tasks, its…

Computation and Language · Computer Science 2021-04-13 Aman Madaan , Yiming Yang

It has been recently observed that the dynamical properties of mass action systems arising from many models of biochemical reaction networks can be derived by considering the corresponding properties of a related generalized mass action…

Numerical Analysis · Mathematics 2014-07-22 Matthew D. Johnston

We present an active learning framework for efficiently generating training data for machine-learned interatomic potentials (MLIPs). The method combines local entropy-driven molecular dynamics with global dataset-aware filtering: a…

Materials Science · Physics 2026-05-21 Meiyan Wang , Rishi Rao , Li Zhu

The practical description of disordered chemical reactions, where reactions involve multiple species at multiple sites, is presently challenge using correlated electronic structure methods. Here we describe the gradient theory of…

Chemical Physics · Physics 2023-04-19 Chenghan Li , Junjie Yang , Xing Zhang , Garnet Kin-Lic Chan

We seek to automate the design of molecules based on specific chemical properties. Our primary contributions are a simpler method for generating SMILES strings guaranteed to be chemically valid, using a combination of a new context-free…

Machine Learning · Computer Science 2018-11-29 Egor Kraev

While machine learning approaches have been successfully used to represent interatomic potentials, their speed has typically lagged behind conventional formalisms. This is often due to the complexity of the structural fingerprints used to…

Materials Science · Physics 2021-02-23 Doyl Dickel , Mashroor Nitol , Christopher Barrett

Understanding molecular structure, dynamics, and reactivity requires bridging processes that occur across widely separated time scales. Conventional molecular dynamics simulations provide atomistic resolution, but their femtosecond time…

Chemical Physics · Physics 2025-10-10 Juan Viguera Diez , Mathias Schreiner , Simon Olsson

PolyMAPS is an open-source library that helps researchers to initialize LAMMPS molecular dynamics simulations. It introduces an integrated workflow by combining preparation, launching, visualization, and analysis into a single Jupyter…

Chemical Physics · Physics 2023-11-14 Xiaoli Yan , Santanu Chaudhuri

We investigate and provide optimal sets of reaction coordinates for mixed pairs of molecules displaying polar, uniaxial, or spherical symmetry in two and three dimensions. These coordinates are non-redundant, i.e., they implicitly involve…

Statistical Mechanics · Physics 2017-05-01 Thomas Heinemann , Sabine H. L. Klapp
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