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This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Large language models (LLMs) exhibit strong medical knowledge and can generate factually accurate responses. However, existing models often fail to account for individual patient contexts, producing answers that are clinically correct yet…

Computation and Language · Computer Science 2026-03-16 Po-Jen Ko , Chen-Han Tsai , Yu-Shao Peng

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Point-of-care transthoracic echocardiography (TTE) enables cardiac assessment in virtually any clinical setting, yet its diagnostic utility remains constrained by the expertise required for image acquisition and interpretation. Visual…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Filippos Bellos , Yutong Li , Jessie N Dong , Zaiyang Guo , Emily Mackay , Yayuan Li , Yannis Avrithis , Alison Pouch , Jason J. Corso

Ensuring the accuracy of responses provided by large language models (LLMs) is crucial, particularly in clinical settings where incorrect information may directly impact patient health. To address this challenge, we construct K-QA, a…

Computation and Language · Computer Science 2024-01-29 Itay Manes , Naama Ronn , David Cohen , Ran Ilan Ber , Zehavi Horowitz-Kugler , Gabriel Stanovsky

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Echocardiographic diagnosis is vital for cardiac screening yet remains challenging. Existing echocardiography foundation models do not effectively capture the relationships between quantitative measurements and clinical manifestations,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Yi Qin , Lehan Wang , Chenxu Zhao , Alex P. W. Lee , Xiaomeng Li

Retrieval-augmented generation (RAG) on specialized domain datasets has shown improved performance when large language models (LLMs) are fine-tuned for generating responses to user queries. In this study, we develop a cybersecurity…

Machine Learning · Computer Science 2024-11-05 Varun Badrinath Krishna

Emerging multimodal large language models (MLLMs) exhibit great potential for chart question answering (CQA). Recent efforts primarily focus on scaling up training datasets (i.e., charts, data tables, and question-answer (QA) pairs) through…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Xingchen Zeng , Haichuan Lin , Yilin Ye , Wei Zeng

Healthcare systems continuously generate vast amounts of electronic health records (EHRs), commonly stored in the Fast Healthcare Interoperability Resources (FHIR) standard. Despite the wealth of information in these records, their…

Computation and Language · Computer Science 2025-01-24 Sara Kothari , Ayush Gupta

We introduce OpenLifelogQA, a large-scale open-ended lifelog QA dataset constructed from 18 months of multimodal lifelog data. Lifelogging is the passive collection and analysis of personal daily activities using wearable devices, producing…

Multimedia · Computer Science 2026-04-30 Quang-Linh Tran , Hoang-Bao Le , Tuong-Nghiem Diep , Binh Nguyen , Gareth J. F. Jones , Cathal Gurrin

Clinical Question Answering (QA) systems enable doctors to quickly access patient information from electronic health records (EHRs). However, training these systems requires significant annotated data, which is limited due to the expertise…

Computation and Language · Computer Science 2024-12-09 Fan Bai , Keith Harrigian , Joel Stremmel , Hamid Hassanzadeh , Ardavan Saeedi , Mark Dredze

Large Language Models (LLMs) have demonstrated impressive performance in various NLP tasks, but they still suffer from challenges such as hallucination and weak numerical reasoning. To overcome these challenges, external tools can be used…

Computation and Language · Computer Science 2023-06-26 Yuchen Zhuang , Yue Yu , Kuan Wang , Haotian Sun , Chao Zhang

The growing volume of academic papers has made it increasingly difficult for researchers to efficiently extract key information. While large language models (LLMs) based agents are capable of automating question answering (QA) workflows for…

Computation and Language · Computer Science 2026-03-31 Tiancheng Huang , Ruisheng Cao , Yuxin Zhang , Zhangyi Kang , Zijian Wang , Chenrun Wang , Yijie Luo , Hang Zheng , Lirong Qian , Lu Chen , Kai Yu

Background: Large language models (LLMs) have seen extraordinary advances with applications in clinical decision support. However, high-quality evidence is urgently needed on the potential and limitation of LLMs in providing accurate…

Artificial Intelligence · Computer Science 2024-09-24 Yuxing Zhi , Yuan Guo , Kai Yuan , Hesong Wang , Heng Xu , Haina Yao , Albert C Yang , Guangrui Huang , Yuping Duan

Electrocardiogram (ECG) is the primary non-invasive diagnostic tool for monitoring cardiac conditions and is crucial in assisting clinicians. Recent studies have concentrated on classifying cardiac conditions using ECG data but have…

Computation and Language · Computer Science 2025-07-09 Zhongwei Wan , Che Liu , Xin Wang , Chaofan Tao , Hui Shen , Jing Xiong , Rossella Arcucci , Huaxiu Yao , Mi Zhang

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse…

Machine Learning · Computer Science 2025-05-09 Jialu Tang , Tong Xia , Yuan Lu , Cecilia Mascolo , Aaqib Saeed

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence. As large language models (LLMs) become increasingly integrated into medical settings, the…

Computation and Language · Computer Science 2025-11-04 Yinuo Wang , Baiyang Wang , Robert E. Mercer , Frank Rudzicz , Sudipta Singha Roy , Pengjie Ren , Zhumin Chen , Xindi Wang