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We propose a disease classification model, called the QC-SPHARM, for the early detection of the Alzheimer's Disease (AD). The proposed QC-SPHARM can distinguish between normal control (NC) subjects and AD patients, as well as between…

Image and Video Processing · Electrical Eng. & Systems 2020-03-24 Anthony Hei-Long Chan , Yishan Luo , Lin Shi , Ronald Lok-Ming Lui

Predicting conversion from Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) is critical for early intervention. Current deep learning paradigms predominantly rely on cross-sectional structural MRI, neglecting prognostic value in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Alireza Moayedikia , Sara Fin , Alicia Troncoso Lora , Uffe Kock Wiil

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jason Qiu

While many quantum computing techniques for machine learning have been proposed, their performance on real-world datasets remains to be studied. In this paper, we explore how a variational quantum circuit could be integrated into a…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Viraj Kulkarni , Sanjesh Pawale , Amit Kharat

Being the most commonly known neurodegeneration, Alzheimer's Disease (AD) is annually diagnosed in millions of patients. The present medical scenario still finds the exact diagnosis and classification of AD through neuroimaging data as a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Pavan Kumar S , Aravintakshan S A

Alzheimer's Disease (AD) is a currently incurable neurodegeneartive disease. Accurately detecting AD, especially in the early stage, represents a high research priority. AD is characterized by progressive cognitive impairments that are…

Machine Learning · Computer Science 2024-08-08 Wenqi Zhu , Yinghua Fu , Ze Wang

This paper presents a new hybrid Quantum Machine Learning (QML) model composed of three elements: a classical computer in charge of the data preparation and interpretation; a Gate-based Quantum Computer running the Variational Quantum…

Quantum Physics · Physics 2024-10-25 Ernesto Acosta , Carlos Cano Gutierrez , Guillermo Botella , Roberto Campos

In this paper, we propose a new methodology to design quantum hybrid diffusion models, derived from classical U-Nets with ResNet and Attention layers. Specifically, we propose two possible different hybridization schemes combining quantum…

Quantum machine learning (QML) offers a promising avenue for advancing representation learning in complex signal domains. In this study, we investigate the use of parameterised quantum circuits (PQCs) for speech emotion recognition (SER) a…

Machine Learning · Computer Science 2025-06-26 Thejan Rajapakshe , Rajib Rana , Farina Riaz , Sara Khalifa , Björn W. Schuller

Multimodal neuroimaging provides complementary structural and functional insights into both human brain organization and disease-related dynamics. Recent studies demonstrate enhanced diagnostic sensitivity for Alzheimer's disease (AD)…

Multimedia · Computer Science 2025-04-24 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

Image and Video Processing · Electrical Eng. & Systems 2021-01-07 Kuo Yang , Emad A. Mohammed

Magnetic resonance image reconstruction starting from undersampled k-space data requires the recovery of many potential nonlinear features, which is very difficult for algorithms to recover these features. In recent years, the development…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Shuo Zhou , Yihang Zhou , Congcong Liu , Yanjie Zhu , Hairong Zheng , Dong Liang , Haifeng Wang

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang

High resolution diffusion MRI (dMRI) data is often constrained by limited scanning time in clinical settings, thus restricting the use of downstream analysis techniques that would otherwise be available. In this work we develop a 3D…

Image and Video Processing · Electrical Eng. & Systems 2022-03-30 Matthew Lyon , Paul Armitage , Mauricio A. Álvarez

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Training machine learning models in an incremental fashion is not only important but also an efficient way to achieve artificial general intelligence. The ability that humans possess of continuous or lifelong learning helps them to not…

Machine Learning · Computer Science 2023-05-18 Sanyam Jain

Many studies on machine learning (ML) for computer-aided diagnosis have so far been mostly restricted to high-quality research data. Clinical data warehouses, gathering routine examinations from hospitals, offer great promises for training…

Image and Video Processing · Electrical Eng. & Systems 2021-04-19 Simona Bottani , Ninon Burgos , Aurélien Maire , Adam Wild , Sebastian Ströer , Didier Dormont , Olivier Colliot

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

Machine Learning · Computer Science 2025-03-20 Chenyu Liu , Luca Rossi

Stacking excessive layers in DNN results in highly underdetermined system when training samples are limited, which is very common in medical applications. In this regard, we present a framework capable of deriving an efficient…

Machine Learning · Computer Science 2025-03-04 Seunghun Baek , Injun Choi , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim