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Due to image blurring image deconvolution is often used for studying biological structures in fluorescence microscopy. Fluorescence microscopy image volumes inherently suffer from intensity inhomogeneity, blur, and are corrupted by various…
Denoising diffusion models have recently shown impressive results in generative tasks. By learning powerful priors from huge collections of training images, such models are able to gradually modify complete noise to a clean natural image…
Image denoising is a fundamental problem in computational photography, where achieving high perception with low distortion is highly demanding. Current methods either struggle with perceptual quality or suffer from significant distortion.…
Complex degradations like noise, blur, and low resolution are typical challenges in real world image fusion tasks, limiting the performance and practicality of existing methods. End to end neural network based approaches are generally…
Volumetric imaging by fluorescence microscopy is often limited by anisotropic spatial resolution from inferior axial resolution compared to the lateral resolution. To address this problem, here we present a deep-learning-enabled…
Visual tokenizers play a crucial role in diffusion models. The dimensionality of latent space governs both reconstruction fidelity and the semantic expressiveness of the latent feature. However, a fundamental trade-off is inherent between…
Robust and accurate nuclei centroid detection is important for the understanding of biological structures in fluorescence microscopy images. Existing automated nuclei localization methods face three main challenges: (1) Most of object…
Probabilistic denoising diffusion models (DDMs) have set a new standard for 2D image generation. Extending DDMs for 3D content creation is an active field of research. Here, we propose TetraDiffusion, a diffusion model that operates on a…
The manifestation of symptoms associated with lung diseases can vary in different depths for individual patients, highlighting the significance of 3D information in CT scans for medical image classification. While Vision Transformer has…
The paper presents a novel approach for vector-floorplan generation via a diffusion model, which denoises 2D coordinates of room/door corners with two inference objectives: 1) a single-step noise as the continuous quantity to precisely…
Large scale text-guided diffusion models have garnered significant attention due to their ability to synthesize diverse images that convey complex visual concepts. This generative power has more recently been leveraged to perform text-to-3D…
Noise is an important issue for radiographic and tomographic imaging techniques. It becomes particularly critical in applications where additional constraints force a strong reduction of the Signal-to-Noise Ratio (SNR) per image. These…
Detection of rare lesions in whole-body CT is fundamentally limited by extreme class imbalance and low target-to-volume ratios, producing precision collapse despite high AUROC. Synthetic augmentation with diffusion models offers promise,…
Discrete Wavelet Transform (DWT) has been widely explored to enhance the performance of image superresolution (SR). Despite some DWT-based methods improving SR by capturing fine-grained frequency signals, most existing approaches neglect…
Miniature fluorescence microscopes are a standard tool in systems biology. However, widefield miniature microscopes capture only 2D information, and modifications that enable 3D capabilities increase the size and weight and have poor…
Neural representations (NRs), such as neural fields and 3D Gaussians, effectively model volumetric data in computed tomography (CT) but suffer from severe artifacts under sparse-view settings. To address this, we propose DiffNR, a novel…
With the great success of diffusion models in image generation, diffusion-based image compression is attracting increasing interests. However, due to the random noise introduced in the diffusion learning, they usually produce…
We present Defocusing Microscopy (DM), a bright-field optical microscopy technique able to perform total 3D imaging of transparent objects. By total 3D imaging we mean the determination of the actual shapes of the upper and lower surfaces…
Image denoising is a fundamental operation in image processing and holds considerable practical importance for various real-world applications. Arguably several thousands of papers are dedicated to image denoising. In the past decade,…
Denoising diffusion models (DDM) have gained recent traction in medical image translation given improved training stability over adversarial models. DDMs learn a multi-step denoising transformation to progressively map random Gaussian-noise…