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Antibody binding site prediction plays a pivotal role in computational immunology and therapeutic antibody design. Existing sequence or structure methods rely on single-view features and fail to identify antibody-specific binding sites on…

Machine Learning · Computer Science 2025-09-12 Hongzong Li , Jiahao Ma , Zhanpeng Shi , Rui Xiao , Fanming Jin , Ye-Fan Hu , Hangjun Che , Jian-Dong Huang

Inference for functional linear models in the presence of heteroscedastic errors has received insufficient attention given its practical importance; in fact, even a central limit theorem has not been studied in this case. At issue,…

Statistics Theory · Mathematics 2024-05-27 Hyemin Yeon , Xiongtao Dai , Daniel John Nordman

How to achieve better end-to-end speech translation (ST) by leveraging (text) machine translation (MT) data? Among various existing techniques, multi-task learning is one of the effective ways to share knowledge between ST and MT in which…

Computation and Language · Computer Science 2023-05-16 Qingkai Fang , Yang Feng

Robust cross-subject emotion recognition from multimodal physiological signals remains a challenging problem, primarily due to modality heterogeneity and inter-subject distribution shift. To tackle these challenges, we propose a novel…

Multimedia · Computer Science 2026-01-30 Jiahao Tang , Youjun Li , Yangxuan Zheng , Xiangting Fan , Siyuan Lu , Nuo Zhang , Zi-Gang Huang

We study the problem of continual test-time adaption where the goal is to adapt a source pre-trained model to a sequence of unlabelled target domains at test time. Existing methods on test-time training suffer from several limitations: (1)…

Machine Learning · Computer Science 2024-10-03 Kien X. Nguyen , Fengchun Qiao , Xi Peng

Existing vision-language model (VLM)-based methods for out-of-distribution (OOD) detection typically rely on similarity scores between input images and in-distribution (ID) text prototypes. However, the modality gap between image and text…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Yimu Wang , Evelien Riddell , Adrian Chow , Sean Sedwards , Krzysztof Czarnecki

Multimodal data is a precious asset enabling a variety of downstream tasks in machine learning. However, real-world data collected across different modalities is often not paired, which is a significant challenge to learn a joint…

Machine Learning · Computer Science 2025-08-11 Mustapha Bounoua , Giulio Franzese , Pietro Michiardi

Multimodal learning has significantly enhanced machine learning performance but still faces numerous challenges and limitations. Imbalanced multimodal learning is one of the problems extensively studied in recent works and is typically…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Shu Shen , C. L. Philip Chen , Tong Zhang

Foundation Vision-Language Models (VLMs) like CLIP exhibit strong generalization capabilities due to large-scale pretraining on diverse image-text pairs. However, their performance often degrades when applied to target datasets with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Debarshi Brahma , Soma Biswas

Test-time adaptation methods have been gaining attention recently as a practical solution for addressing source-to-target domain gaps by gradually updating the model without requiring labels on the target data. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Taeyeop Lee , Jonathan Tremblay , Valts Blukis , Bowen Wen , Byeong-Uk Lee , Inkyu Shin , Stan Birchfield , In So Kweon , Kuk-Jin Yoon

Parameter-efficient fine-tuning (PEFT) in multimodal tracking reveals a concerning trend where recent performance gains are often achieved at the cost of inflated parameter budgets, which fundamentally erodes PEFT's efficiency promise. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Junbin Su , Ziteng Xue , Shihui Zhang , Kun Chen , Weiming Hu , Zhipeng Zhang

Multimodal Large Language Models (MLLMs) often exhibit significant modality preference, which is a tendency to favor one modality over another. Depending on the input, they may over-rely on linguistic priors relative to visual evidence, or…

Machine Learning · Computer Science 2026-02-16 Zihan Huang , Xintong Li , Rohan Surana , Tong Yu , Rui Wang , Julian McAuley , Jingbo Shang , Junda Wu

Continual learning in environments with shifting data distributions is a challenging problem with several real-world applications. In this paper we consider settings in which the data distribution(task) shifts abruptly and the timing of…

Machine Learning · Computer Science 2022-01-07 Mengda Xu , Sumitra Ganesh , Pranay Pasula

Current deep learning based text classification methods are limited by their ability to achieve fast learning and generalization when the data is scarce. We address this problem by integrating a meta-learning procedure that uses the…

Cross-topic automated essay scoring (AES) aims to develop a transferable model capable of effectively evaluating essays on a target topic. A significant challenge in this domain arises from the inherent discrepancies between topics. While…

Computation and Language · Computer Science 2025-08-11 Chunyun Zhang , Hongyan Zhao , Chaoran Cui , Qilong Song , Zhiqing Lu , Shuai Gong , Kailin Liu

Entropy minimization has been widely used in unsupervised domain adaptation (UDA). However, existing works reveal that entropy minimization only may result into collapsed trivial solutions. In this paper, we propose to avoid trivial…

Machine Learning · Computer Science 2020-02-06 Xiaofu Wu , Suofei hang , Quan Zhou , Zhen Yang , Chunming Zhao , Longin Jan Latecki

Machine learning methods strive to acquire a robust model during the training process that can effectively generalize to test samples, even in the presence of distribution shifts. However, these methods often suffer from performance…

Machine Learning · Computer Science 2024-12-13 Jian Liang , Ran He , Tieniu Tan

Metric learning seeks perceptual embeddings where visually similar instances are close and dissimilar instances are apart, but learned representations can be sub-optimal when the distribution of intra-class samples is diverse and distinct…

Machine Learning · Computer Science 2021-08-30 Elad Levi , Tete Xiao , Xiaolong Wang , Trevor Darrell

In model checking for regressions, nonparametric estimation-based tests usually have tractable limiting null distributions and are sensitive to oscillating alternative models, but suffer from the curse of dimensionality. In contrast,…

Methodology · Statistics 2019-03-12 Lingzhu Li , Xuehu Zhu , Lixing Zhu

This paper proposes a novel test-time adaptation strategy that adjusts the model pre-trained on the source domain using only unlabeled online data from the target domain to alleviate the performance degradation due to the distribution shift…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Sungha Choi , Seunghan Yang , Seokeon Choi , Sungrack Yun