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Integrated analysis of multi-omics datasets holds great promise for uncovering complex biological processes. However, the large dimension of omics data poses significant interpretability and multiple testing challenges. Simultaneous…

Methodology · Statistics 2024-10-28 Mitra Ebrahimpoor , Renee Menezes , Ningning Xu , Jelle J. Goeman

The study of Planktonic Foraminifera abundances permits to obtain climatic curves on the basis of percentage ratio between tropical and temperate/polar forms. Climatic changes were controlled by several phenomena as: (i) Milankovitch's…

Populations and Evolution · Quantitative Biology 2007-05-23 A. Caruso , M. E. Gargano , D. Valenti , A. Fiasconaro , B. Spagnolo

Spatially resolved genetic data is increasingly used to reconstruct the migrational history of species. To assist such inference, we study, by means of simulations and analytical methods, the dynamics of neutral gene frequencies in a…

Populations and Evolution · Quantitative Biology 2008-01-15 Oskar Hallatschek , David R. Nelson

The transport of heat and solutes by vertically migrating aggregations of plankton has long been explored as a potentially important source of ocean mixing. However, direct evidence of enhanced mixing due to these migrations remains…

Biological Physics · Physics 2023-04-05 Matt K. Fu , John O. Dabiri

In this work we use the random matrix theory (RMT) to correctly describethe behavior of spectral statistical properties of the sea surface temperatureof oceans. This oceanographic variable plays an important role in theglobalclimate system.…

Atmospheric and Oceanic Physics · Physics 2020-07-07 Eucymara F. N. Santosa , Anderson L. R. Barbosa , Paulo J. Duarte-Neto

The search for biosignatures necessitates developing our understanding of life under different conditions. If life can influence the climate evolution of its planet then understanding the behaviour of life-climate feedbacks under extreme…

Earth and Planetary Astrophysics · Physics 2023-04-05 A. E. Nicholson , N. J. Mayne

The current progress in the detection of terrestrial type exoplanets has opened a new avenue in the characterization of exoplanetary atmospheres and in the search for biosignatures of life with the upcoming ground-based and space missions.…

Comparative studies of cancer-related genes allow us to gain novel information about the evolution and function of these genes, but also to understand cancer as a driving force in biological systems and species life histories. So far,…

Populations and Evolution · Quantitative Biology 2021-12-15 Ciara Baines , Richard Meitern , Randel Kreitsberg , Tuul Sepp

Organisms often grow, migrate and compete in liquid environments, as well as on solid surfaces. However, relatively little is known about what happens when competing species are mixed and compressed by fluid turbulence. In these lectures we…

Populations and Evolution · Quantitative Biology 2015-06-04 Roberto Benzi , Mogens H. Jensen , David R. Nelson , Prasad Perlekar , Simone Pigolotti , Federico Toschi

Phenomics is concerned with detailed description of all aspects of organisms, from their physical foundations at genetic, molecular and cellular level, to behavioural and psychological traits. Neuropsychiatric phenomics, endorsed by NIMH,…

Neurons and Cognition · Quantitative Biology 2021-01-13 Włodzisław Duch

In this research, we consider a mixture of genome fragments of a certain bacteria set. The problem of mixture separation is studied under the assumption that all the genomes present in the mixture are completely sequenced or are close to…

Genomics · Quantitative Biology 2012-03-12 Valery Kirzhner , Zeev Volkovich

Advancing ocean science has a significant impact to the development of the world, from operating a safe navigation for vessels to maintaining a healthy and diverse ocean ecosystem. Various ocean software systems have been extensively…

Software Engineering · Computer Science 2022-06-14 Quang-Hung Luu , Huai Liu , Tsong Yueh Chen , Hai L. Vu

Populations of widely distributed species often encounter and adapt to specific environmental conditions. However, comprehensive characterization of the genetic basis of adaptation is demanding, requiring genome-wide genotype data, multiple…

Populations and Evolution · Quantitative Biology 2013-08-01 Tanja Pyhäjärvi , Matthew B. Hufford , Sofiane Mezmouk , Jeffrey Ross-Ibarra

Complexity in biology is often described using a multi-map architecture, where the genotype, representing the encoded information, is mapped to the functional level, known as the phenotype, which is then connected to a latent phenotype we…

Other Quantitative Biology · Quantitative Biology 2024-02-06 Juan F Poyatos

1. An understanding of how biodiversity confers ecosystem stability is crucial in managing ecosystems under major environmental changes. Multiple biodiversity drivers can stabilize ecosystem functions over time. However, we know little…

Sequence differences between the strains of bacteria comprising host-associated and environmental microbiota may play a role in community assembly and influence the resilience of microbial communities to disturbances. Tools for…

Determining mechanistic models of gene regulation, especially underlying phenotypic variation, is a central goal of both mathematical biology and modern evolutionary biology. However, several challenges, involving both common…

Molecular Networks · Quantitative Biology 2025-11-04 Cody E. FitzGerald , Shelley Reich , Victor Agaba , Arjun Mathur , Michael S. Werner , Niall M. Mangan

Microbial communities assemble through a complex set of interactions between microbes and their environment, and the resulting metabolic impact on the host ecosystem can be profound. Microbial activity is known to impact human health, plant…

Quantitative Methods · Quantitative Biology 2023-11-09 James D. Brunner , Laverne A. Gallegos-Graves , Marie E. Kroeger

The detection of massive planets orbiting nearby stars has become almost routine, but current techniques are as yet unable to detect terrestrial planets with masses comparable to the Earth's. Future space-based observatories to detect…

Astrophysics · Physics 2015-06-24 E. B. Ford , S. Seager , E. L. Turner

Many species of phytoplankton migrate vertically near the surface of the ocean, either in search of light or nutrients. These motile organisms are affected by ocean waves at the surface. We derive a set of wave-averaged equations to…