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Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Current hyperspectral anomaly detection (HAD) benchmark datasets suffer from low resolution, simple background, and small size of the detection data. These factors also limit the performance of the well-known low-rank representation (LRR)…

Image and Video Processing · Electrical Eng. & Systems 2024-02-26 Chenyu Li , Bing Zhang , Danfeng Hong , Jing Yao , Jocelyn Chanussot

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Brain imaging of mental health, neurodevelopmental and learning disorders has coupled with machine learning to identify patients based only on their brain activation, and ultimately identify features that generalize from smaller samples of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Laura Tomaz Da Silva , Nathalia Bianchini Esper , Duncan D. Ruiz , Felipe Meneguzzi , Augusto Buchweitz

Dysarthria is a speech disorder characterized by impaired intelligibility and reduced communicative effectiveness. Automatic dysarthria assessment provides a scalable, cost-effective approach for supporting the diagnosis and treatment of…

Audio and Speech Processing · Electrical Eng. & Systems 2025-11-05 Kaimeng Jia , Minzhu Tu , Zengrui Jin , Siyin Wang , Chao Zhang

Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…

Computation and Language · Computer Science 2019-06-14 Flavio Di Palo , Natalie Parde

We introduce a wide and deep neural network for prediction of progression from patients with mild cognitive impairment to Alzheimer's disease. Information from anatomical shape and tabular clinical data (demographics, biomarkers) are fused…

Machine Learning · Computer Science 2020-04-01 Sebastian Pölsterl , Ignacio Sarasua , Benjamín Gutiérrez-Becker , Christian Wachinger

Linguistic anomalies detectable in spontaneous speech have shown promise for various clinical applications including screening for dementia and other forms of cognitive impairment. The feasibility of deploying automated tools that can…

Audio and Speech Processing · Electrical Eng. & Systems 2022-11-15 Changye Li , Trevor Cohen , Serguei Pakhomov

Background and Aim: Accurate classification of Magnetic Resonance Images (MRI) is essential to accurately predict Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) conversion. Meanwhile, deep learning has been successfully…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Kshitiz Shrestha , Omar Hisham Alsadoon , Abeer Alsadoon , Tarik A. Rashid , Rasha S. Ali , P. W. C. Prasad , Oday D. Jerew

This study targets to automatically annotate on arrhythmia by deep network. The investigated types include sinus rhythm, asystole (Asys), supraventricular tachycardia (Tachy), ventricular flutter or fibrillation (VF/VFL), ventricular…

Signal Processing · Electrical Eng. & Systems 2023-02-13 Weijia Lu , Jie Shuai , Shuyan Gu , Joel Xue

Early diagnosis of Autism Spectrum Disorder (ASD) is an effective and favorable step towards enhancing the health and well-being of children with ASD. Manual ASD diagnosis testing is labor-intensive, complex, and prone to human error due to…

Artificial Intelligence · Computer Science 2024-09-30 Chinthaka Ranasingha , Harshala Gammulle , Tharindu Fernando , Sridha Sridharan , Clinton Fookes

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

We propose a lesion-aware graph neural network (LEGNet) to predict language ability from resting-state fMRI (rs-fMRI) connectivity in patients with post-stroke aphasia. Our model integrates three components: an edge-based learning module…

Machine Learning · Computer Science 2024-09-05 Zijian Chen , Maria Varkanitsa , Prakash Ishwar , Janusz Konrad , Margrit Betke , Swathi Kiran , Archana Venkataraman

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Articulatory features are inherently invariant to acoustic signal distortion and have been successfully incorporated into automatic speech recognition (ASR) systems designed for normal speech. Their practical application to atypical task…

Audio and Speech Processing · Electrical Eng. & Systems 2023-06-23 Shujie Hu , Xurong Xie , Mengzhe Geng , Mingyu Cui , Jiajun Deng , Guinan Li , Tianzi Wang , Xunying Liu , Helen Meng

In this work, we investigate the joint use of articulatory and acoustic features for automatic speech recognition (ASR) of pathological speech. Despite long-lasting efforts to build speaker- and text-independent ASR systems for people with…

Computation and Language · Computer Science 2018-07-31 Emre Yılmaz , Vikramjit Mitra , Chris Bartels , Horacio Franco

Millions of people live with cognitive impairment from Alzheimer's disease and related dementias (ADRD). Voice-enabled smart home systems offer promise for supporting daily living but rely on automatic speech recognition (ASR) to transcribe…

Human-Computer Interaction · Computer Science 2026-03-02 Michelle Cohn , Alyssa Lanzi , Yui Ishihara , Chen-Nee Chuah , Georgia Zellou , Alyssa Weakley

Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…

Computation and Language · Computer Science 2025-06-12 Yao Xiao , Heidi Christensen , Stefan Goetze