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We show that a Gaussian Process model can be combined with a small number (of order 100) of scattering calculations to provide a multi-dimensional dependence of scattering observables on the experimentally controllable parameters such as…

Chemical Physics · Physics 2015-08-19 Jie Cui , Roman V. Krems

Aqueous solubility (AS) is a key physiochemical property that plays a crucial role in drug discovery and material design. We report a novel unified approach to predict and infer chemical compounds with the desired AS based on simple…

Machine Learning · Computer Science 2024-09-09 Muniba Batool , Naveed Ahmed Azam , Jianshen Zhu , Kazuya Haraguchi , Liang Zhao , Tatsuya Akutsu

Quantum machine learning (QML) has great potential for the analysis of chemical datasets. However, conventional quantum data-encoding schemes, such as fingerprint encoding, are generally unfeasible for the accurate representation of…

Quantum Physics · Physics 2025-11-18 Choy Boy , Edoardo Altamura , Dilhan Manawadu , Ivano Tavernelli , Stefano Mensa , David J. Wales

The quasiparticle interference (QPI) technique is a powerful tool that allows to uncover the structure and properties of electronic structure of a material combined with scattering properties of defects at surfaces. Recently this technique…

Mesoscale and Nanoscale Physics · Physics 2020-06-11 Philipp Rüßmann , Phivos Mavropoulos , Stefan Blügel

QCMPI is a quantum computer (QC) simulation package written in Fortran 90 with parallel processing capabilities. It is an accessible research tool that permits rapid evaluation of quantum algorithms for a large number of qubits and for…

Quantum Physics · Physics 2015-05-13 F. Tabakin , B. Julia-Diaz

Gaussian process regression (GPR) is a useful technique to predict composition--property relationships in glasses as the method inherently provides the standard deviation of the predictions. However, the technique remains restricted to…

Computational Physics · Physics 2020-07-07 Suresh Bishnoi , R. Ravinder , Hargun Singh , Hariprasad Kodamana , N. M. Anoop Krishnan

Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models for binary classification of genome sequence data by…

Machine Learning · Computer Science 2025-01-15 Navneet Singh , Shiva Raj Pokhrel

Accurately predicting response properties of molecules such as the dynamic polarizability and hyperpolarizability using quantum mechanics has been a long-standing challenge with widespread applications in material and drug design. Classical…

Chemical Physics · Physics 2020-09-01 Xiaoxia Cai , Wei-Hai Fang , Heng Fan , Zhendong Li

Simulations of colloidal suspensions consisting of mesoscopic particles and smaller species such as ions or depletants are computationally challenging as different length and time scales are involved. Here, we introduce a machine learning…

Soft Condensed Matter · Physics 2021-12-01 Gerardo Campos-Villalobos , Emanuele Boattini , Laura Filion , Marjolein Dijkstra

We present a unique, multitask dataset comprising 143 drug and drug candidate molecules, each evaluated on in vitro, parallel artificial-membrane permeability assays (PAMPA) using six different model membranes. Using this resource, we…

Machine Learning · Computer Science 2026-05-04 Andrs Formanek , Anna Vincze , Richrd Bicsak , Yves Moreau , Gyorgy T. Balogh , Adam Arany

Polymers exhibit complex architectures and diverse properties that place them at the center of contemporary research in chemistry and materials science. As conventional computational techniques, even multi-scale ones, struggle to capture…

Quantum Physics · Physics 2025-12-23 Alexandrina Stoyanova , Bogdan Penkovsky

Copolymers are highly versatile materials with a vast range of possible chemical compositions. By using computational methods for property prediction, the design of copolymers can be accelerated, allowing for the prioritization of…

Materials Science · Physics 2025-09-16 Elaheh Kazemi-Khasragh , Rocío Mercado , Carlos Gonzalez , Maciej Haranczyk

Particle identification in large high-energy physics experiments typically relies on classifiers obtained by combining many experimental observables. Predicting the probability density function (pdf) of such classifiers in the multivariate…

High Energy Physics - Experiment · Physics 2022-02-11 Giacomo Graziani , Lucio Anderlini , Saverio Mariani , Edoardo Franzoso , Luciano Libero Pappalardo , Pasquale di Nezza

Evaluating the health effects of complex environmental mixtures remains a central challenge in environmental health research. Existing approaches vary in their flexibility, interpretability, scalability, and support for diverse outcome…

Applications · Statistics 2025-12-15 Hyungrok Do , Yuyan Wang , Mengling Liu , Myeonggyun Lee

Virtual screening can accelerate drug discovery by identifying promising candidates for experimental evaluation. Machine learning is a powerful method for screening, as it can learn complex structure-property relationships from experimental…

Machine Learning · Computer Science 2021-02-22 Simon Axelrod , Rafael Gomez-Bombarelli

Aerosol particles play an important role in the climate system by absorbing and scattering radiation and influencing cloud properties. They are also one of the biggest sources of uncertainty for climate modeling. Many climate models do not…

Machine Learning · Computer Science 2022-07-26 Paula Harder , Duncan Watson-Parris , Philip Stier , Dominik Strassel , Nicolas R. Gauger , Janis Keuper

Polymers are diverse and versatile materials that have met a wide range of material application demands. They come in several flavors and architectures, e.g., homopolymers, copolymers, polymer blends, and polymers with additives. Searching…

Soft Condensed Matter · Physics 2024-11-05 Shivank S. Shukla , Christopher Kuenneth , Rampi Ramprasad

Gaussian quantum probes have been widely used in quantum metrology and thermometry, where the goal is to estimate the temperature of an environment with which the probe interacts. It was recently shown that introducing initial…

Quantum simulation provides a powerful route for exploring many-body phenomena beyond the capabilities of classical computation. Existing approaches typically proceed in the forward direction: a model Hamiltonian is specified, implemented…

We present ChemXploreML, a modular desktop application designed for machine learning-based molecular property prediction. The framework's flexible architecture allows integration of any molecular embedding technique with modern machine…

Chemical Physics · Physics 2025-05-14 Aravindh Nivas Marimuthu , Brett A. McGuire