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Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…
Spatial transcriptomics (ST) provides high-resolution pathological images and whole-transcriptomic expression profiles at individual spots across whole-slide scales. This setting makes it an ideal data source to develop multimodal…
Recently, machine learning-based semantic segmentation algorithms have demonstrated their potential to accurately segment regions and contours in medical images, allowing the precise location of anatomical structures and abnormalities.…
Spine segmentation, based on ultrasound volume projection imaging (VPI), plays a vital role for intelligent scoliosis diagnosis in clinical applications. However, this task faces several significant challenges. Firstly, the global…
The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…
There has been a significant increase from 2010 to 2016 in the number of people suffering from spine problems. The automatic image segmentation of the spine obtained from a computed tomography (CT) image is important for diagnosing spine…
Rectal cancer is one of the most common diseases and a major cause of mortality. For deciding rectal cancer treatment plans, T-staging is important. However, evaluating the index from preoperative MRI images requires high radiologists'…
Accurate segmentation of laryngo-pharyngeal tumors is crucial for precise diagnosis and effective treatment planning. However, traditional single-modality imaging methods often fall short of capturing the complex anatomical and pathological…
In this work, we address the challenge of binary lung nodule classification (benign vs malignant) using CT images by proposing a multi-level attention stacked ensemble of deep neural networks. Three pretrained backbones -- EfficientNet V2…
The Cobb angle that quantitatively evaluates the spinal curvature plays an important role in the scoliosis diagnosis and treatment. Conventional measurement of these angles suffers from huge variability and low reliability due to intensive…
We propose a novel convolutional method for the detection and identification of vertebrae in whole spine MRIs. This involves using a learnt vector field to group detected vertebrae corners together into individual vertebral bodies and…
We propose a general pipeline to automate the extraction of labels from radiology reports using large language models, which we validate on spinal MRI reports. The efficacy of our labelling method is measured on five distinct conditions:…
Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…
MR imaging is a valuable diagnostic tool allowing to non-invasively visualize patient anatomy and pathology with high soft-tissue contrast. However, MRI acquisition is typically time-consuming, leading to patient discomfort and increased…
In clinical settings, the screening, diagnosis, and monitoring of adolescent idiopathic scoliosis (AIS) typically involve physical or radiographic examinations. However, physical examinations are subjective, while radiographic examinations…
Deep learning approach has been demonstrated to automatically segment the bilateral mandibular canals from CBCT scans, yet systematic studies of its clinical and technical validation are scarce. To validate the mandibular canal localization…
Glaucoma is one of the major eye diseases that leads to progressive optic nerve fiber damage and irreversible blindness, afflicting millions of individuals. Glaucoma forecast is a good solution to early screening and intervention of…
Synthesizing medical images while preserving their structural information is crucial in medical research. In such scenarios, the preservation of anatomical content becomes especially important. Although recent advances have been made by…
Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…
Ultrasound spine imaging technique has been applied to the assessment of spine deformity. However, manual measurements of scoliotic angles on ultrasound images are time-consuming and heavily rely on raters experience. The objectives of this…