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Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…
Health monitoring systems have revolutionized modern healthcare by enabling the continuous capture of physiological and behavioral data, essential for preventive measures and early health intervention. While integrating this data with Large…
Depression is debilitating, and not uncommon. Indeed, studies of excessive social media users show correlations with depression, ADHD, and other mental health concerns. Given that there is a large number of people with excessive social…
Depression is a prominent health challenge to the world, and early risk detection (ERD) of depression from online posts can be a promising technique for combating the threat. Early depression detection faces the challenge of efficiently…
Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…
Causality detection and mining are important tasks in information retrieval due to their enormous use in information extraction, and knowledge graph construction. To solve these tasks, in existing literature there exist several solutions --…
Large Language Models (LLMs) showcase remarkable abilities, yet they struggle with limitations such as hallucinations, outdated knowledge, opacity, and inexplicable reasoning. To address these challenges, Retrieval-Augmented Generation…
Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more…
Early detection and treatment of depression is essential in promoting remission, preventing relapse, and reducing the emotional burden of the disease. Current diagnoses are primarily subjective, inconsistent across professionals, and…
Difficult decision-making problems abound in various disciplines and domains. The proliferation of generative techniques, especially large language models (LLMs), has excited interest in using them for decision support. However, LLMs cannot…
Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…
Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…
Depression is a pervasive mental health condition that affects hundreds of millions of individuals worldwide, yet many cases remain undiagnosed due to barriers in traditional clinical access and pervasive stigma. Social media platforms, and…
Timely and accurate diagnosis of neurodegenerative disorders, such as Alzheimer's disease, is central to disease management. Existing deep learning models require large-scale annotated datasets and often function as "black boxes".…
Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…
Difficult-to-treat depression (DTD) has been proposed as a broader and more clinically comprehensive perspective on a person's depressive disorder where despite treatment, they continue to experience significant burden. We sought to develop…
Retrieval-Augmented Generation (RAG) lifts the factuality of Large Language Models (LLMs) by injecting external knowledge, yet it falls short on problems that demand multi-step inference; conversely, purely reasoning-oriented approaches…
Retrieval-augmented generation (RAG) enhances LLMs with external knowledge, yet generation remains vulnerable to retrieval-induced noise and uncertain placement of relevant chunks, often causing hallucinations. We present Ext2Gen, an…
Models that accurately detect depression from text are important tools for addressing the post-pandemic mental health crisis. BERT-based classifiers' promising performance and the off-the-shelf availability make them great candidates for…
The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…