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Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Health monitoring systems have revolutionized modern healthcare by enabling the continuous capture of physiological and behavioral data, essential for preventive measures and early health intervention. While integrating this data with Large…

Machine Learning · Computer Science 2024-06-26 Ajan Subramanian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Depression is debilitating, and not uncommon. Indeed, studies of excessive social media users show correlations with depression, ADHD, and other mental health concerns. Given that there is a large number of people with excessive social…

Computation and Language · Computer Science 2023-10-04 Dean Ninalga

Depression is a prominent health challenge to the world, and early risk detection (ERD) of depression from online posts can be a promising technique for combating the threat. Early depression detection faces the challenge of efficiently…

Computation and Language · Computer Science 2022-05-20 Zhiling Zhang , Siyuan Chen , Mengyue Wu , Kenny Q. Zhu

Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…

Causality detection and mining are important tasks in information retrieval due to their enormous use in information extraction, and knowledge graph construction. To solve these tasks, in existing literature there exist several solutions --…

Computation and Language · Computer Science 2025-06-02 Thushara Manjari Naduvilakandy , Hyeju Jang , Mohammad Al Hasan

Large Language Models (LLMs) showcase remarkable abilities, yet they struggle with limitations such as hallucinations, outdated knowledge, opacity, and inexplicable reasoning. To address these challenges, Retrieval-Augmented Generation…

Computation and Language · Computer Science 2024-10-03 Sourav Verma

Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Song , William Han , Tony Chen , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Early detection and treatment of depression is essential in promoting remission, preventing relapse, and reducing the emotional burden of the disease. Current diagnoses are primarily subjective, inconsistent across professionals, and…

Machine Learning · Computer Science 2020-02-03 Karol Chlasta , Krzysztof Wołk , Izabela Krejtz

Difficult decision-making problems abound in various disciplines and domains. The proliferation of generative techniques, especially large language models (LLMs), has excited interest in using them for decision support. However, LLMs cannot…

Artificial Intelligence · Computer Science 2025-09-16 Boris Kovalerchuk , Brent D. Fegley

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…

Artificial Intelligence · Computer Science 2024-12-24 Francisco de Arriba-Pérez , Silvia García-Méndez

Depression is a pervasive mental health condition that affects hundreds of millions of individuals worldwide, yet many cases remain undiagnosed due to barriers in traditional clinical access and pervasive stigma. Social media platforms, and…

Computation and Language · Computer Science 2025-08-06 Eliseo Bao , Anxo Pérez , Javier Parapar

Timely and accurate diagnosis of neurodegenerative disorders, such as Alzheimer's disease, is central to disease management. Existing deep learning models require large-scale annotated datasets and often function as "black boxes".…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Duy-Cat Can , Quang-Huy Tang , Huong Ha , Binh T. Nguyen , Oliver Y. Chén

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

Machine Learning · Computer Science 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

Difficult-to-treat depression (DTD) has been proposed as a broader and more clinically comprehensive perspective on a person's depressive disorder where despite treatment, they continue to experience significant burden. We sought to develop…

Computation and Language · Computer Science 2024-02-13 Isabelle Lorge , Dan W. Joyce , Niall Taylor , Alejo Nevado-Holgado , Andrea Cipriani , Andrey Kormilitzin

Retrieval-Augmented Generation (RAG) lifts the factuality of Large Language Models (LLMs) by injecting external knowledge, yet it falls short on problems that demand multi-step inference; conversely, purely reasoning-oriented approaches…

Retrieval-augmented generation (RAG) enhances LLMs with external knowledge, yet generation remains vulnerable to retrieval-induced noise and uncertain placement of relevant chunks, often causing hallucinations. We present Ext2Gen, an…

Computation and Language · Computer Science 2025-11-18 Hwanjun Song , Jeonghwan Choi , Minseok Kim

Models that accurately detect depression from text are important tools for addressing the post-pandemic mental health crisis. BERT-based classifiers' promising performance and the off-the-shelf availability make them great candidates for…

Computation and Language · Computer Science 2022-09-13 Jekaterina Novikova , Ksenia Shkaruta

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

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