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\textit{Objective:} Gadolinium-based contrast agents (GBCAs) have been widely used to better visualize disease in brain magnetic resonance imaging (MRI). However, gadolinium deposition within the brain and body has raised safety concerns…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Chao Chen , Catalina Raymond , Bill Speier , Xinyu Jin , Timothy F. Cloughesy , Dieter Enzmann , Benjamin M. Ellingson , Corey W. Arnold

Magnetic resonance imaging (MRI) is the most sensitive technique for breast cancer detection among current clinical imaging modalities. Contrast-enhanced MRI (CE-MRI) provides superior differentiation between tumors and invaded healthy…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Tianyu Zhang , Luyi Han , Anna D'Angelo , Xin Wang , Yuan Gao , Chunyao Lu , Jonas Teuwen , Regina Beets-Tan , Tao Tan , Ritse Mann

Contrast-enhanced magnetic resonance imaging (CE-MRI) plays a crucial role in brain tumor assessment; however, its acquisition requires gadolinium-based contrast agents (GBCAs), which increase costs and raise safety concerns. Consequently,…

Image and Video Processing · Electrical Eng. & Systems 2026-03-23 Atharva Rege , Adinath Madhavrao Dukre , Numan Balci , Dwarikanath Mahapatra , Imran Razzak

Gadolinium-based contrast agents (GBCAs) are central to glioma imaging but raise safety, cost, and accessibility concerns. Predicting contrast enhancement from non-contrast MRI using machine learning (ML) offers a safer alternative, as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Sajad Amiri , Shahram Taeb , Sara Gharibi , Setareh Dehghanfard , Somayeh Sadat Mehrnia , Mehrdad Oveisi , Ilker Hacihaliloglu , Arman Rahmim , Mohammad R. Salmanpour

Magnetic resonance imaging (MRI) is a leading modality for the diagnosis of liver cancer, significantly improving the classification of the lesion and patient outcomes. However, traditional MRI faces challenges including risks from contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Xiaojiao Xiao , Jianfeng Zhao , Qinmin Vivian Hu , Guanghui Wang

Cardiomyopathy, a principal contributor to heart failure and sudden cardiac mortality, demands precise early screening. Cardiac Magnetic Resonance (CMR), recognized as the diagnostic 'gold standard' through multiparametric protocols, holds…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Siqing Yuan , Yulin Wang , Zirui Cao , Yueyan Wang , Zehao Weng , Hui Wang , Lei Xu , Zixian Chen , Lei Chen , Zhong Xue , Dinggang Shen

Contrast-enhanced magnetic resonance imaging (MRI) is pivotal in the pipeline of brain tumor segmentation and analysis. Gadolinium-based contrast agents, as the most commonly used contrast agents, are expensive and may have potential side…

Image and Video Processing · Electrical Eng. & Systems 2024-06-25 Lujun Gui , Chuyang Ye , Tianyi Yan

Objective: Gadolinium-based contrast agents (GBCAs) are commonly used in MRI scans of patients with gliomas to enhance brain tumor characterization using T1-weighted (T1W) MRI. However, there is growing concern about GBCA toxicity. This…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Zach Eidex , Mojtaba Safari , Richard L. J. Qiu , David S. Yu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Gadolinium-based contrast agents (GBCAs) are widely used in magnetic resonance imaging (MRI) to enhance lesion detection and characterisation, particularly in the field of neuro-oncology. Nevertheless, concerns regarding gadolinium…

Image and Video Processing · Electrical Eng. & Systems 2025-10-03 Pierre Fayolle , Alexandre Bône , Noëlie Debs , Philippe Robert , Pascal Bourdon , Remy Guillevin , David Helbert

Modern magnetic resonance imaging (MRI) relies on application-specific multi-channel receive coils to achieve high performance, but these coils are typically costly, rigid, and difficult to generalize across anatomies. Recent wireless,…

Medical Physics · Physics 2026-05-26 Yuhan Liu , Xia Zhu , Ke Wu , Artem Kaliaev , Christina A. LeBedis , Stephan W. Anderson , Xin Zhang

Deep learning (DL) based contrast dose reduction and elimination in MRI imaging is gaining traction, given the detrimental effects of Gadolinium-based Contrast Agents (GBCAs). These DL algorithms are however limited by the availability of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Dayang Wang , Srivathsa Pasumarthi , Greg Zaharchuk , Ryan Chamberlain

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Contrast enhancement by Gadolinium-based contrast agents (GBCAs) is a vital tool for tumor diagnosis in neuroradiology. Based on brain MRI scans of glioblastoma before and after Gadolinium administration, we address enhancement prediction…

Image and Video Processing · Electrical Eng. & Systems 2024-10-14 Moritz Piening , Fabian Altekrüger , Gabriele Steidl , Elke Hattingen , Eike Steidl

Fine-grained Vision-Language Pre-training (FVLP) demonstrates significant potential in 3D medical image understanding by aligning anatomy-level visual representations with corresponding textual descriptions. However, existing FVLP paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Hanwen Zhang , Yao Liu , Die Dai , Jiaye Yang , Qiao Liu , Yutong Xie , Peng Wang

Integrating functional magnetic resonance imaging (fMRI) connectivity data with phenotypic textual descriptors (e.g., disease label, demographic data) holds significant potential to advance our understanding of neurological conditions.…

Machine Learning · Computer Science 2025-03-31 Yanting Yang , Xiaoxiao Li

Despite that deep learning (DL) methods have presented tremendous potential in many medical image analysis tasks, the practical applications of medical DL models are limited due to the lack of enough data samples with manual annotations. By…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Zhiyang Liu , Dong Yang , Minghao Zhang , Hanyu Sun , Hong Wu , Huiying Wang , Wen Shen , Chao Chai , Shuang Xia

Multi-contrast magnetic resonance imaging (MRI) super-resolution intends to reconstruct high-resolution (HR) images from low-resolution (LR) scans by leveraging structural information present in HR reference images acquired with different…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Xianming Gu , Lihui Wang , Ying Cao , Zeyu Deng , Yingfeng Ou , Guodong Hu , Yi Chen

Recently, deep learning (DL)-based methods have been proposed for the computational reduction of gadolinium-based contrast agents (GBCAs) to mitigate adverse side effects while preserving diagnostic value. Currently, the two main challenges…

Multi-modal magnetic resonance imaging (MRI) is essential for providing complementary information about brain anatomy and pathology, leading to more accurate diagnoses. However, obtaining high-quality multi-modal MRI in a clinical setting…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Minjoo Lim , Bogyeong Kang , Tae-Eui Kam

Multi-contrast magnetic resonance imaging (MRI) plays a vital role in brain tumor segmentation and diagnosis by leveraging complementary information from different contrasts. Each contrast highlights specific tumor characteristics, enabling…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Zhenxuan Zhang , Hongjie Wu , Jiahao Huang , Baihong Xie , Zhifan Gao , Junxian Du , Pete Lally , Guang Yang
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