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A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

The ability to generate diverse 3D articulated head avatars is vital to a plethora of applications, including augmented reality, cinematography, and education. Recent work on text-guided 3D object generation has shown great promise in…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Alexander W. Bergman , Wang Yifan , Gordon Wetzstein

To bring digital avatars into people's lives, it is highly demanded to efficiently generate complete, realistic, and animatable head avatars. This task is challenging, and it is difficult for existing methods to satisfy all the requirements…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Sijing Wu , Yichao Yan , Yunhao Li , Yuhao Cheng , Wenhan Zhu , Ke Gao , Xiaobo Li , Guangtao Zhai

Motivation: Gene expression during brain development or abnormal development is a biological process that is highly dynamic in spatio and temporal. Due to the lack of comprehensive integration of spatial and temporal dimensions of brain…

Quantitative Methods · Quantitative Biology 2023-10-19 Shanjun Mao , Xiao Huang , Runjiu Chen , Chenyang Zhang , Yizhu Diao , Zongjin Li , Qingzhe Wang , Shan Tang , Shuixia Guo

Methods for resolving the 3D microstructure of the brain typically start by thinly slicing and staining the brain, and then imaging each individual section with visible light photons or electrons. In contrast, X-rays can be used to image…

The meninges, located between the skull and brain, are composed of three membrane layers: the pia, the arachnoid, and the dura. Reconstruction of these layers can aid in studying volume differences between patients with neurodegenerative…

Image and Video Processing · Electrical Eng. & Systems 2023-04-14 Peiyu Duan , Yuan Xue , Shuo Han , Lianrui Zuo , Aaron Carass , Caitlyn Bernhard , Savannah Hays , Peter A. Calabresi , Susan M. Resnick , James S. Duncan , Jerry L. Prince

The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Nurislam Tursynbek , Marc Niethammer

There are multiple scales of abstraction from which we can describe the same image, depending on whether we are focusing on fine-grained details or a more global attribute of the image. In brain mapping, learning to automatically parse…

Brain signal visualization has emerged as an active research area, serving as a critical interface between the human visual system and computer vision models. Although diffusion models have shown promise in analyzing functional magnetic…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Bohan Zeng , Shanglin Li , Xuhui Liu , Sicheng Gao , Xiaolong Jiang , Xu Tang , Yao Hu , Jianzhuang Liu , Baochang Zhang

Automatic and reliable quantitative tools for MR brain image analysis are a very valuable resources for both clinical and research environments. In the last years, this field has experienced many advances with successful techniques based on…

Diffusion models have shown impressive potential on talking head generation. While plausible appearance and talking effect are achieved, these methods still suffer from temporal, 3D or expression inconsistency due to the error accumulation…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Haijie Yang , Zhenyu Zhang , Hao Tang , Jianjun Qian , Jian Yang

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Accurate quantification of tau pathology via tau positron emission tomography (PET) scan is crucial for diagnosing and monitoring Alzheimer's disease (AD). However, the high cost and limited availability of tau PET restrict its widespread…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yuxin Gong , Se-in Jang , Wei Shao , Yi Su , Kuang Gong

Accurate brain tumor segmentation is crucial for neuro-oncology diagnosis and treatment planning. Deep learning methods have made significant progress, but automatic segmentation still faces challenges, including tumor morphological…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Mingda Zhang

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg

Numerical simulations rely on constructing accurate and detailed models to produce reliable results - a task that is often challenging. This task becomes notably more difficult when the model is of the human brain. We create an anatomically…

Computational Engineering, Finance, and Science · Computer Science 2024-10-11 Andy Huynh , Benjamin Zwick , Mostafa Jamshidian , Michael Halle , Adam Wittek , Karol Miller

Multi-regional interaction among neuronal populations underlies the brain's processing of rich sensory information in our daily lives. Recent neuroscience and neuroimaging studies have increasingly used naturalistic stimuli and experimental…

Neurons and Cognition · Quantitative Biology 2021-06-08 Yu Takagi , Laurence T. Hunt , Ryu Ohata , Hiroshi Imamizu , Jun-ichiro Hirayama

Magnetic resonance imaging of fetal and neonatal brains reveals rapid neurodevelopment marked by substantial anatomical changes unfolding within days. Studying this critical stage of the developing human brain, therefore, requires accurate…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Maik Dannecker , Vasiliki Sideri-Lampretsa , Sophie Starck , Angeline Mihailov , Mathieu Milh , Nadine Girard , Guillaume Auzias , Daniel Rueckert

Mined Semantic Analysis (MSA) is a novel concept space model which employs unsupervised learning to generate semantic representations of text. MSA represents textual structures (terms, phrases, documents) as a Bag of Concepts (BoC) where…

Computation and Language · Computer Science 2018-01-03 Walid Shalaby , Wlodek Zadrozny