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Text-to-image generation has important implications for generation of diverse and controllable images. Several attempts have been made to adapt Stable Diffusion (SD) to the medical domain. However, the large distribution difference between…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Peng Huang , Xue Gao , Lihong Huang , Jing Jiao , Xiaokang Li , Yuanyuan Wang , Yi Guo

High-resolution image synthesis remains a core challenge in generative modeling, particularly in balancing computational efficiency with the preservation of fine-grained visual detail. We present Latent Wavelet Diffusion (LWD), a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Luigi Sigillo , Shengfeng He , Danilo Comminiello

Objective: While recent advances in text-conditioned generative models have enabled the synthesis of realistic medical images, progress has been largely confined to 2D modalities such as chest X-rays. Extending text-to-image generation to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Daniele Molino , Camillo Maria Caruso , Filippo Ruffini , Paolo Soda , Valerio Guarrasi

Long-tailed class distributions are pervasive in multi-class medical datasets and pose significant challenges for deep learning models which typically underperform on tail classes with limited samples. This limitation is particularly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Jiaxiang Jiang , Mahesh Subedar , Omesh Tickoo

Large-scale datasets with high-quality labels are desired for training accurate deep learning models. However, due to the annotation cost, datasets in medical imaging are often either partially-labeled or small. For example, DeepLesion is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ke Yan , Jinzheng Cai , Youjing Zheng , Adam P. Harrison , Dakai Jin , Youbao Tang , Yuxing Tang , Lingyun Huang , Jing Xiao , Le Lu

Text-guided diffusion models have shown superior performance in image/video generation and editing. While few explorations have been performed in 3D scenarios. In this paper, we discuss three fundamental and interesting problems on this…

Computer Vision and Pattern Recognition · Computer Science 2023-10-13 Gang Li , Heliang Zheng , Chaoyue Wang , Chang Li , Changwen Zheng , Dacheng Tao

The tremendous progress in neural image generation, coupled with the emergence of seemingly omnipotent vision-language models has finally enabled text-based interfaces for creating and editing images. Handling generic images requires a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Omri Avrahami , Ohad Fried , Dani Lischinski

Layer compositing is one of the most popular image editing workflows among both amateurs and professionals. Motivated by the success of diffusion models, we explore layer compositing from a layered image generation perspective. Instead of…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Xinyang Zhang , Wentian Zhao , Xin Lu , Jeff Chien

Medical image analysis plays a pivotal role in the early diagnosis of diseases such as skin lesions. However, the scarcity of data and the class imbalance significantly hinder the performance of deep learning models. We propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Zhaobin Xu

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

Deep learning algorithms require extensive data to achieve robust performance. However, data availability is often restricted in the medical domain due to patient privacy concerns. Synthetic data presents a possible solution to these…

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

This study explores the utilization of Dermatoscopic synthetic data generated through stable diffusion models as a strategy for enhancing the robustness of machine learning model training. Synthetic data generation plays a pivotal role in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Muhammad Ali Farooq , Wang Yao , Michael Schukat , Mark A Little , Peter Corcoran

In layout-to-image (L2I) synthesis, controlled complex scenes are generated from coarse information like bounding boxes. Such a task is exciting to many downstream applications because the input layouts offer strong guidance to the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Ruyu Wang , Xuefeng Hou , Sabrina Schmedding , Marco F. Huber

While diffusion models have significantly advanced the quality of image generation their capability to accurately and coherently render text within these images remains a substantial challenge. Conventional diffusion-based methods for scene…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Qilong Zhangli , Jindong Jiang , Di Liu , Licheng Yu , Xiaoliang Dai , Ankit Ramchandani , Guan Pang , Dimitris N. Metaxas , Praveen Krishnan

Despite recent advances in deep generative modeling, skin lesion classification systems remain constrained by the limited availability of large, diverse, and well-annotated clinical datasets, resulting in class imbalance between benign and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Stathis Galanakis , Alexandros Koliousis , Stefanos Zafeiriou

Skin images from real-world clinical practice are often limited, resulting in a shortage of training data for deep-learning models. While many studies have explored skin image synthesis, existing methods often generate low-quality images…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Jiajun Sun , Zhen Yu , Siyuan Yan , Jason J. Ong , Zongyuan Ge , Lei Zhang

Diffusion models have attracted significant attention due to the remarkable ability to create content and generate data for tasks like image classification. However, the usage of diffusion models to generate the high-quality object…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Kai Chen , Enze Xie , Zhe Chen , Yibo Wang , Lanqing Hong , Zhenguo Li , Dit-Yan Yeung

Although computer-aided diagnosis (CADx) and detection (CADe) systems have made significant progress in various medical domains, their application is still limited in specialized fields such as otorhinolaryngology. In the latter, current…

Image and Video Processing · Electrical Eng. & Systems 2025-08-11 Chiara Baldini , Kaisar Kushibar , Richard Osuala , Simone Balocco , Oliver Diaz , Karim Lekadir , Leonardo S. Mattos

Building generic robotic manipulation systems often requires large amounts of real-world data, which can be dificult to collect. Synthetic data generation offers a promising alternative, but limiting the sim-to-real gap requires significant…

Robotics · Computer Science 2024-11-18 Thomas Lips , Francis wyffels