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Diffusion models have emerged as a powerful class of generative models for molecular design, capable of capturing complex structural distributions and achieving high fidelity in 3D molecule generation. However, their widespread use remains…

Machine Learning · Computer Science 2026-01-15 Adrita Das , Peiran Jiang , Dantong Zhu , Barnabas Poczos , Jose Lugo-Martinez

Reparameterized diffusion models (RDMs) have recently matched autoregressive methods in protein generation, motivating their use for challenging tasks such as designing membrane proteins, which possess interleaved soluble and transmembrane…

Biomolecules · Quantitative Biology 2025-09-30 Shrey Goel , Peregrine M. Schray , Yinuo Zhang , Sophia Vincoff , Huong T. Kratochvil , Pranam Chatterjee

Masked diffusion models (MDMs) have emerged as a promising alternative to autoregressive models for language modeling, yet the effective design of transformer architectures for MDMs remains underexplored. In this paper, we show that…

Machine Learning · Computer Science 2026-05-26 Sanghyun Lee , Chunsan Hong , Seungryong Kim , Jonghyun Lee , Jongho Park , Dongmin Park

Discrete diffusion has emerged as a powerful framework for generative modeling in discrete domains, yet efficiently sampling from these models remains challenging. Existing sampling strategies often struggle to balance computation and…

Machine Learning · Computer Science 2025-11-12 Yixiu Zhao , Jiaxin Shi , Feng Chen , Shaul Druckmann , Lester Mackey , Scott Linderman

Masked diffusion language models enable parallel token generation and offer improved decoding efficiency over autoregressive models. However, their performance degrades significantly when generating multiple tokens simultaneously, due to a…

Computation and Language · Computer Science 2026-05-12 Houxing Ren , Mingjie Zhan , Zimu Lu , Ke Wang , Yunqiao Yang , Haotian Hou , Junting Pan , Hongsheng Li

While latent diffusion models (LDMs), such as Stable Diffusion, are designed for high-resolution (HR) image generation, they often struggle with significant structural distortions when generating images at resolutions higher than their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Boyuan Cao , Jiaxin Ye , Yujie Wei , Hongming Shan

Language models with recurrent depth, also referred to as universal or looped when considering transformers, are defined by the capacity to increase their computation through the repetition of layers. Recent efforts in pretraining have…

Machine Learning · Computer Science 2025-10-17 Jonas Geiping , Xinyu Yang , Guinan Su

Masked diffusion models (MDMs) have shown promise in language modeling, yet their scalability and effectiveness in core language tasks, such as text generation and language understanding, remain underexplored. This paper establishes the…

Artificial Intelligence · Computer Science 2025-03-03 Shen Nie , Fengqi Zhu , Chao Du , Tianyu Pang , Qian Liu , Guangtao Zeng , Min Lin , Chongxuan Li

Diffusion models that are based on iterative denoising have been recently proposed and leveraged in various generation tasks like image generation. Whereas, as a way inherently built for continuous data, existing diffusion models still have…

Computation and Language · Computer Science 2023-04-11 Jiaao Chen , Aston Zhang , Mu Li , Alex Smola , Diyi Yang

Recently, research on denoising diffusion models has expanded its application to the field of image restoration. Traditional diffusion-based image restoration methods utilize degraded images as conditional input to effectively guide the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Zhenning Shi , Haoshuai Zheng , Chen Xu , Changsheng Dong , Bin Pan , Xueshuo Xie , Along He , Tao Li , Huazhu Fu

Discrete diffusion models have emerged as a promising direction for vision-language tasks, offering bidirectional context modeling and theoretical parallelization. However, their practical application is severely hindered by a…

Computation and Language · Computer Science 2025-10-24 Yatai Ji , Teng Wang , Yuying Ge , Zhiheng Liu , Sidi Yang , Ying Shan , Ping Luo

Masked discrete diffusion models (MDMs) are a promising new approach to generative modelling, offering the ability for parallel token generation and therefore greater efficiency than autoregressive counterparts. However, achieving an…

Machine Learning · Computer Science 2026-03-02 David Fox , Sam Bowyer , Song Liu , Laurence Aitchison , Raul Santos-Rodriguez , Mengyue Yang

Instructional video editing applies edits to an input video using only text prompts, enabling intuitive natural-language control. Despite rapid progress, most methods still require fixed-length inputs and substantial compute. Meanwhile,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Mohammadreza Salehi , Mehdi Noroozi , Luca Morreale , Ruchika Chavhan , Malcolm Chadwick , Alberto Gil Ramos , Abhinav Mehrotra

Diffusion language models have recently emerged as a competitive alternative to autoregressive language models. Beyond next-token generation, they are more efficient and flexible by enabling parallel and any-order token generation. However,…

Machine Learning · Computer Science 2025-11-18 Chenxiao Yang , Cai Zhou , David Wipf , Zhiyuan Li

Diffusion language models intrinsically fail to capture correlations between decoded tokens, which leads to a harsh trade-off between sampling quality and throughput. To solve this issue, we propose DiLaDiff, a variant of masked diffusion…

Machine Learning · Computer Science 2026-05-25 Jean-Marie Lemercier , Tomas Geffner , Karsten Kreis , Morteza Mardani , Arash Vahdat , Ante Jukić

Masked diffusion models have recently emerged as a flexible framework for discrete generative modeling. However, a key limitation of standard masked diffusion is its inability to effectively capture dependencies among tokens that are…

Machine Learning · Computer Science 2025-10-28 Yichi Zhang , Alex Schwing , Zhizhen Zhao

Masked Diffusion Models (MDMs) have emerged as a powerful generative modeling technique. Despite their remarkable results, they typically suffer from slow inference with several steps. In this paper, we propose Di$\mathtt{[M]}$O, a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Yuanzhi Zhu , Xi Wang , Stéphane Lathuilière , Vicky Kalogeiton

We propose a novel diffusion model, termed the non-identical diffusion model, and investigate its application to wireless orthogonal frequency division multiplexing (OFDM) channel generation. Unlike the standard diffusion model that uses a…

Signal Processing · Electrical Eng. & Systems 2026-01-30 Yuzhi Yang , Omar Alhussein , Mérouane Debbah

Masked (or absorbing) diffusion is actively explored as an alternative to autoregressive models for generative modeling of discrete data. However, existing work in this area has been hindered by unnecessarily complex model formulations and…

Machine Learning · Computer Science 2025-01-17 Jiaxin Shi , Kehang Han , Zhe Wang , Arnaud Doucet , Michalis K. Titsias

We present a novel method for exemplar-based image translation, called matching interleaved diffusion models (MIDMs). Most existing methods for this task were formulated as GAN-based matching-then-generation framework. However, in this…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Junyoung Seo , Gyuseong Lee , Seokju Cho , Jiyoung Lee , Seungryong Kim