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Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

The advent of large language models (LLMs), such as GPT, Gemini, and DeepSeek, has significantly advanced natural language processing, giving rise to sophisticated chatbots capable of diverse language-related tasks. The transition from…

Computation and Language · Computer Science 2025-06-16 Jiachen Zhu , Menghui Zhu , Renting Rui , Rong Shan , Congmin Zheng , Bo Chen , Yunjia Xi , Jianghao Lin , Weiwen Liu , Ruiming Tang , Yong Yu , Weinan Zhang

This study evaluates large language models (LLMs) in generating code from algorithm descriptions in recent NLP papers. The task requires two key competencies: (1) algorithm comprehension: synthesizing information from papers and academic…

Computation and Language · Computer Science 2025-08-08 Yanzheng Xiang , Hanqi Yan , Shuyin Ouyang , Lin Gui , Yulan He

As the mathematical capabilities of large language models (LLMs) improve, it becomes increasingly important to evaluate their performance on research-level tasks at the frontier of mathematical knowledge. However, existing benchmarks are…

Large language models (LLMs) now support automated software security tasks, including vulnerability discovery and proof-of-concept (PoC) generation. Existing benchmarks do not faithfully evaluate LLMs in real-world bug hunting scenarios…

Cryptography and Security · Computer Science 2026-05-27 Hwiwon Lee , Jiawei Liu , Dongjun Kim , Ziqi Zhang , Chunqiu Steven Xia , Lingming Zhang

Recent advances in large language models (LLMs) have significantly impacted data science workflows, giving rise to specialized data science agents designed to automate analytical tasks. Despite rapid adoption, systematic benchmarks…

Artificial Intelligence · Computer Science 2025-08-08 Ram Mohan Rao Kadiyala , Siddhant Gupta , Jebish Purbey , Giulio Martini , Ali Shafique , Suman Debnath , Hamza Farooq

Generative AI agents, software systems powered by Large Language Models (LLMs), are emerging as a promising approach to automate cybersecurity tasks. Among the others, penetration testing is a challenging field due to the task complexity…

Cryptography and Security · Computer Science 2024-10-29 Luca Gioacchini , Marco Mellia , Idilio Drago , Alexander Delsanto , Giuseppe Siracusano , Roberto Bifulco

Recently, there has been a growing interest among large language model (LLM) developers in LLM-based document reading systems, which enable users to upload their own documents and pose questions related to the document contents, going…

Computation and Language · Computer Science 2024-07-16 Anni Zou , Wenhao Yu , Hongming Zhang , Kaixin Ma , Deng Cai , Zhuosheng Zhang , Hai Zhao , Dong Yu

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…

Task automation has been greatly empowered by the recent advances in Large Language Models (LLMs) via Python code, where the tasks ranging from software engineering development to general-purpose reasoning. While current benchmarks have…

While Large Language Models (LLMs) show significant potential in hardware engineering, current benchmarks suffer from saturation and limited task diversity, failing to reflect LLMs' performance in real industrial workflows. To address this…

Artificial Intelligence · Computer Science 2026-02-03 Zhongkai Yu , Chenyang Zhou , Yichen Lin , Hejia Zhang , Haotian Ye , Junxia Cui , Zaifeng Pan , Jishen Zhao , Yufei Ding

Large Language Models (LLMs) hold significant potential for advancing fact-checking by leveraging their capabilities in reasoning, evidence retrieval, and explanation generation. However, existing benchmarks fail to comprehensively evaluate…

Computation and Language · Computer Science 2025-06-17 Shuo Yang , Yuqin Dai , Guoqing Wang , Xinran Zheng , Jinfeng Xu , Jinze Li , Zhenzhe Ying , Weiqiang Wang , Edith C. H. Ngai

Pre-trained language models (LMs) have become ubiquitous in solving various natural language processing (NLP) tasks. There has been increasing interest in what knowledge these LMs contain and how we can extract that knowledge, treating LMs…

Computation and Language · Computer Science 2021-09-16 Mujeen Sung , Jinhyuk Lee , Sean Yi , Minji Jeon , Sungdong Kim , Jaewoo Kang

LLM-based agents are increasingly expected to handle real-world assistant tasks, yet existing benchmarks typically evaluate them under isolated sources of difficulty, such as a single environment or fully specified instructions. This leaves…

Computation and Language · Computer Science 2026-04-16 Xiang Long , Li Du , Yilong Xu , Fangcheng Liu , Haoqing Wang , Ning Ding , Ziheng Li , Jianyuan Guo , Yehui Tang

Autonomous agents powered by large language models (LLMs) are increasingly deployed in real-world applications requiring complex, long-horizon workflows. However, existing benchmarks predominantly focus on atomic tasks that are…

Computation and Language · Computer Science 2025-08-13 Weixuan Wang , Dongge Han , Daniel Madrigal Diaz , Jin Xu , Victor Rühle , Saravan Rajmohan

The rapid evolution and use of Large Language Models (LLMs) in professional workflows require an evaluation of their domain-specific knowledge against industry standards. We introduceCyberCertBench, a new suite of Multiple Choice Question…

Cryptography and Security · Computer Science 2026-04-23 Gustav Keppler , Ghada Elbez , Veit Hagenmeyer

Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex,…

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

The performance of large language models (LLMs) on existing reasoning benchmarks has significantly improved over the past years. In response, we present JEEBench, a considerably more challenging benchmark dataset for evaluating the problem…

Computation and Language · Computer Science 2023-10-24 Daman Arora , Himanshu Gaurav Singh , Mausam

Autonomous language-model agents are increasingly evaluated on long-horizon tool-use tasks, but existing benchmarks rarely capture the complexity and nuance of real scientific work. To address this gap, we introduce Collider-Bench, a…

Machine Learning · Computer Science 2026-05-15 Darius A. Faroughy , Sofia Palacios Schweitzer , Ian Pang , Siddharth Mishra-Sharma , David Shih