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Contemporary benchmark methods for image inpainting are based on deep generative models and specifically leverage adversarial loss for yielding realistic reconstructions. However, these models cannot be directly applied on image/video…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 Avisek Lahiri , Arnav Jain , Prabir Kumar Biswas , Pabitra Mitra

Conditional waveform synthesis models learn a distribution of audio waveforms given conditioning such as text, mel-spectrograms, or MIDI. These systems employ deep generative models that model the waveform via either sequential…

Audio and Speech Processing · Electrical Eng. & Systems 2022-03-07 Max Morrison , Rithesh Kumar , Kundan Kumar , Prem Seetharaman , Aaron Courville , Yoshua Bengio

We consider controllable DNA sequence design, where sequences are generated by conditioning on specific biological properties. While language models (LMs) such as GPT and BERT have achieved remarkable success in natural language generation,…

Machine Learning · Computer Science 2025-12-10 Xingyu Su , Xiner Li , Yuchao Lin , Ziqian Xie , Degui Zhi , Shuiwang Ji

Retrieval-Augmented Generation (RAG) encounters efficiency challenges when scaling to massive knowledge bases while preserving contextual relevance. We propose Hash-RAG, a framework that integrates deep hashing techniques with systematic…

Information Retrieval · Computer Science 2025-06-04 Jinyu Guo , Xunlei Chen , Qiyang Xia , Zhaokun Wang , Jie Ou , Libo Qin , Shunyu Yao , Wenhong Tian

Retrieval-Augmented Generation (RAG) improves large language models by retrieving external knowledge, often truncated into smaller chunks due to the input context window, which leads to information loss, resulting in response hallucinations…

Computation and Language · Computer Science 2025-11-18 Jie Zhang , Bo Tang , Wanzi Shao , Wenqiang Wei , Jihao Zhao , Jianqing Zhu , Zhiyu li , Wen Xi , Zehao Lin , Feiyu Xiong , Yanchao Tan

Static malware analysis remains a core technique in cybersecurity due to its ability to assess potentially malicious software without execution. Nevertheless, many existing static approaches rely on handcrafted features or curated datasets…

Cryptography and Security · Computer Science 2026-05-07 Thesath Wijayasiri , Kar Wai Fok , Vrizlynn L. L. Thing

Conditional generative adversarial networks (cGANs) have been widely researched to generate class conditional images using a single generator. However, in the conventional cGANs techniques, it is still challenging for the generator to learn…

Computer Vision and Pattern Recognition · Computer Science 2020-04-09 Min-Cheol Sagong , Yong-Goo Shin , Yoon-Jae Yeo , Seung Park , Sung-Jea Ko

Unconditional generation -- the problem of modeling data distribution without relying on human-annotated labels -- is a long-standing and fundamental challenge in generative models, creating a potential of learning from large-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Tianhong Li , Dina Katabi , Kaiming He

Packet classification is a core function in software-defined networks, and learning-based methods have recently shown significant throughput gains on large-scale rulesets. However, existing learning-based approaches struggle with…

Networking and Internet Architecture · Computer Science 2026-01-07 Zhengyu Liao , Shiyou Qian

Deep generative models have been applied with increasing success to the generation of two dimensional molecules as SMILES strings and molecular graphs. In this work we describe for the first time a deep generative model that can generate 3D…

Chemical Physics · Physics 2020-11-24 Tomohide Masuda , Matthew Ragoza , David Ryan Koes

Diffusion models offer a powerful means of capturing the manifold of realistic protein structures, enabling rapid design for protein engineering tasks. However, existing approaches observe critical failure modes when precise constraints are…

Biomolecules · Quantitative Biology 2026-03-27 Jacob K. Christopher , Austin Seamann , Jingyi Cui , Sagar Khare , Ferdinando Fioretto

Conditional Generative Adversarial Networks (cGAN) were designed to generate images based on the provided conditions, \eg, class-level distributions. However, existing methods have used the same generating architecture for all classes. This…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Peng Zhou , Lingxi Xie , Xiaopeng Zhang , Bingbing Ni , Qi Tian

We study a fundamental problem in structure-based drug design -- generating molecules that bind to specific protein binding sites. While we have witnessed the great success of deep generative models in drug design, the existing methods are…

Biomolecules · Quantitative Biology 2022-11-15 Shitong Luo , Jiaqi Guan , Jianzhu Ma , Jian Peng

While generative models have recently become ubiquitous in many scientific areas, less attention has been paid to their evaluation. For molecular generative models, the state-of-the-art examines their output in isolation or in relation to…

Domains such as logo synthesis, in which the data has a high degree of multi-modality, still pose a challenge for generative adversarial networks (GANs). Recent research shows that progressive training (ProGAN) and mapping network…

Machine Learning · Computer Science 2019-09-24 Cedric Oeldorf , Gerasimos Spanakis

The abstract mathematical rules of artificial neural network (ANN) are implemented through computation using electronic computers, photonics and in-vitro DNA computation. Here we demonstrate the physical realization of ANN in living…

Biological Physics · Physics 2020-01-06 Kathakali Sarkar , Deepro Bonnerjee , Sangram Bagh

Multi-organ segmentation of X-ray images is of fundamental importance for computer aided diagnosis systems. However, the most advanced semantic segmentation methods rely on deep learning and require a huge amount of labeled images, which…

Image and Video Processing · Electrical Eng. & Systems 2021-11-19 Giorgio Ciano , Paolo Andreini , Tommaso Mazzierli , Monica Bianchini , Franco Scarselli

Natural language processing models often face challenges due to limited labeled data, especially in domain specific areas, e.g., clinical trials. To overcome this, text augmentation techniques are commonly used to increases sample size by…

Computation and Language · Computer Science 2025-04-08 Charco Hui , Yalu Wen

Graph generation generally aims to create new graphs that closely align with a specific graph distribution. Existing works often implicitly capture this distribution through the optimization of generators, potentially overlooking the…

Machine Learning · Computer Science 2024-07-19 Song Wang , Zhen Tan , Xinyu Zhao , Tianlong Chen , Huan Liu , Jundong Li

The recent success of large foundation models in artificial intelligence has prompted the emergence of chemical pre-trained models. Despite the growing interest in large molecular pre-trained models that provide informative representations…

Machine Learning · Computer Science 2025-05-26 Jinho Chang , Jong Chul Ye