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Cervical cancer is a leading malignancy in female reproductive system. While AI-assisted cytology offers a cost-effective and non-invasive screening solution, current systems struggle with generalizability in complex clinical scenarios. To…

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2013-07-08 Chris Roadknight , Uwe Aickelin , Alex Ladas , Daniele Soria , John Scholefield , Lindy Durrant

Colorectal cancer (CRC) remains a significant cause of cancer-related mortality, despite the widespread implementation of prophylactic initiatives aimed at detecting and removing precancerous polyps. Although screening effectively reduces…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Ahmed Rahu , Brian Shula , Brandon Combs , Aqsa Sultana , Surendra P. Singh , Vijayan K. Asari , Derrick Forchetti

We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

Cancer development is a multistep process often starting with a single cell in which a number of epigenetic and genetic alterations have accumulated thus transforming it into a tumor cell. The progeny of such a single benign tumor cell…

Tissues and Organs · Quantitative Biology 2022-09-21 Steffen Lange , Richard Mogwitz , Denis Hünniger , Anja Voss-Böhme

Background: Colorectal adenocarcinoma (CRC) remains a leading cause of cancer-related mortality worldwide, with variable patient outcomes despite treatment advances. Traditional prognostic methods based on clinicopathological variables…

Quantitative Methods · Quantitative Biology 2025-07-28 Oluwafemi Ogundare

Accurate detection of colorectal cancer and early prevention heavily rely on precise polyp identification during gastrointestinal colonoscopy. Due to limited data, many current state-of-the-art deep learning methods for polyp segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Ankush Gajanan Arudkar , Bernard J. E. Evans

Breast cancer is a common and deadly disease, but it is often curable when diagnosed early. While most countries have large-scale screening programs, there is no consensus on a single globally accepted guideline for breast cancer screening.…

Artificial Intelligence · Computer Science 2023-06-27 Robert K. Helmeczi , Can Kavaklioglu , Mucahit Cevik , Davood Pirayesh Neghab

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Following recent advancements in computer-aided detection and diagnosis systems for colonoscopy, the automated reporting of colonoscopy procedures is set to further revolutionize clinical practice. A crucial yet underexplored aspect in the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Carlo Biffi , Giorgio Roffo , Pietro Salvagnini , Andrea Cherubini

The solution here proposed can be used to conduct economic analysis in randomized clinical trials. It is based on a statistical approach and aims at calculating a revised version of the incremental costeffective ratio (ICER) in order to…

Applications · Statistics 2013-06-19 C. D'Urso

Colorectal endoscopy is important for the early detection and treatment of colorectal cancer and is used worldwide. A computer-aided diagnosis (CAD) system that provides an objective measure to endoscopists during colorectal endoscopic…

Computer Vision and Pattern Recognition · Computer Science 2016-12-22 Tsubasa Hirakawa , Toru Tamaki , Bisser Raytchev , Kazufumi Kaneda , Tetsushi Koide , Shigeto Yoshida , Hiroshi Mieno , Shinji Tanaka

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

Colorectal cancer refers to the cancer from the dentate line to the junction of rectosigmoid colon, which is one of the most common malignant tumors of the digestive tract. The treatment of colorectal cancer is controversial, so…

Other Quantitative Biology · Quantitative Biology 2022-02-09 Boda Xie

Automated segmentation tools often encounter accuracy and adaptability issues when applied to images of different pathology. The purpose of this study is to explore the feasibility of building a workflow to efficiently route images to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Peilong Wang , Timothy L. Kline , Andy D. Missert , Cole J. Cook , Matthew R. Callstrom , Alex Chan , Robert P. Hartman , Zachary S. Kelm , Panagiotis Korfiatis

Dynamic treatment regimes (DTR) are sequential decision rules corresponding to several stages of intervention. Each rule maps patients' covariates to optional treatments. The optimal dynamic treatment regime is the one that maximizes the…

Methodology · Statistics 2023-10-10 Zhishuai Liu , Zishu Zhan , Jian Liu , Danhui Yi , Cunjie Lin , Yufei Yang

Purpose: The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback during interventions, real-time in-vivo imaging with confocal laser microscopy has…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Nils Gessert , Marcel Bengs , Lukas Wittig , Daniel Drömann , Tobias Keck , Alexander Schlaefer , David B. Ellebrecht

The primary analysis of randomized screening trials for cancer typically adheres to the intention-to-screen principle, measuring cancer-specific mortality reductions between screening and control arms. These mortality reductions result from…

Methodology · Statistics 2021-07-30 Sudipta Saha , Zhihui Liu , Olli Saarela

In recent years, colorectal cancer has become one of the most significant diseases that endanger human health. Deep learning methods are increasingly important for the classification of colorectal histopathology images. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-08 Haoyuan Chen , Chen Li , Xiaoyan Li , Md Mamunur Rahaman , Weiming Hu , Yixin Li , Wanli Liu , Changhao Sun , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek

Colorectal cancer (CRC) is the third most common cause of cancer diagnosed in the United States and the second leading cause of cancer-related death among both genders. Notably, CRC is the leading cause of cancer in younger men less than 50…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Nikhil Kumar Tomar , Debesh Jha , Koushik Biswas , Tyler M. Berzin , Rajesh Keswani , Michael Wallace , Ulas Bagci