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Accurate grading of Conjunctival Melanocytic Intraepithelial Lesions (CMIL) is essential for treatment and melanoma prediction but remains difficult due to subtle morphological cues and interrelated diagnostic criteria. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Mert Ikinci , Luna Toma , Karin U. Loeffler , Leticia Ussem , Daniela Süsskind , Julia M. Weller , Yousef Yeganeh , Martina C. Herwig-Carl , Shadi Albarqouni

Multiple instance learning (MIL) is a key algorithm for classification of whole slide images (WSI). Histology WSIs can have billions of pixels, which create enormous computational and annotation challenges. Typically, such images are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-03 Andriy Myronenko , Ziyue Xu , Dong Yang , Holger Roth , Daguang Xu

Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 So Won Jeong , Veronika Ročková

We present a novel weakly-supervised framework for classifying whole slide images (WSIs). WSIs, due to their gigapixel resolution, are commonly processed by patch-wise classification with patch-level labels. However, patch-level labels…

Computer Vision and Pattern Recognition · Computer Science 2022-03-10 Tiange Xiang , Yang Song , Chaoyi Zhang , Dongnan Liu , Mei Chen , Fan Zhang , Heng Huang , Lauren O'Donnell , Weidong Cai

Mammograms are commonly employed in the large scale screening of breast cancer which is primarily characterized by the presence of malignant masses. However, automated image-level detection of malignancy is a challenging task given the…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Sarath Chandra K , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Few-shot fine-grained image classification (FS-FGIC) presents a significant challenge, requiring models to distinguish visually similar subclasses with limited labeled examples. Existing methods have critical limitations: metric-based…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Ning Luo , Meiyin Hu , Huan Wan , Yanyan Yang , Zhuohang Jiang , Xin Wei

This paper proposes a probabilistic deep metric learning (PDML) framework for hyperspectral image classification, which aims to predict the category of each pixel for an image captured by hyperspectral sensors. The core problem for…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Chengkun Wang , Wenzhao Zheng , Xian Sun , Jiwen Lu , Jie Zhou

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Medical image classification plays a crucial role in computer-aided clinical diagnosis. While deep learning techniques have significantly enhanced efficiency and reduced costs, the privacy-sensitive nature of medical imaging data…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Sufen Ren , Yule Hu , Shengchao Chen , Guanjun Wang

described by multiple instances (e.g., image patches) and simultaneously associated with multiple labels. Existing MIML methods are useful in many applications but most of which suffer from relatively low accuracy and training efficiency…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Qi Lai , Jianhang Zhou , Yanfen Gan , Chi-Man Vong , Deshuang Huang

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Jialong Huang , Gaojie Li , Shichao Kan , Jianfeng Liu , Yixiong Liang

Transvaginal ultrasound is a critical imaging modality for evaluating cervical anatomy and detecting physiological changes. However, accurate segmentation of cervical structures remains challenging due to low contrast, shadow artifacts, and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Tran Quoc Khanh Le , Nguyen Lan Vi Vu , Ha-Hieu Pham , Xuan-Loc Huynh , Tien-Huy Nguyen , Minh Huu Nhat Le , Quan Nguyen , Hien D. Nguyen

Histopathological cancer diagnostics has become more complex, and the increasing number of biopsies is a challenge for most pathology laboratories. Thus, development of automatic methods for evaluation of histopathological cancer sections…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 André Pedersen , Erik Smistad , Tor V. Rise , Vibeke G. Dale , Henrik S. Pettersen , Tor-Arne S. Nordmo , David Bouget , Ingerid Reinertsen , Marit Valla

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Extracting quantitative phenotypic information from whole-slide images presents significant challenges for investigators who are not experienced in developing image analysis algorithms. We present new software that enables rapid…

Deep Neural Networks (DNNs) have shown remarkable success in various computer vision tasks. However, their black-box nature often leads to difficulty in interpreting their decisions, creating an unfilled need for methods to explain the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Daniel Siegismund , Mario Wieser , Stephan Heyse , Stephan Steigele

Histopathology slides are routinely marked by pathologists using permanent ink markers that should not be removed as they form part of the medical record. Often tumour regions are marked up for the purpose of highlighting features or other…

Computer Vision and Pattern Recognition · Computer Science 2019-05-14 Sharib Ali , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Melanie Lubrano di Scandalea , Christian S. Perone , Mathieu Boudreau , Julien Cohen-Adad