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Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

A common strategy for fact-checking long-form content generated by Large Language Models (LLMs) is extracting simple claims that can be verified independently. Since inaccurate or incomplete claims compromise fact-checking results, ensuring…

Computation and Language · Computer Science 2025-06-09 Dasha Metropolitansky , Jonathan Larson

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Rule-based reasoning over natural language input arises in domains where decisions must be auditable and justifiable: clinical protocols specify eligibility criteria in prose, evidence rules define admissibility through textual conditions,…

Artificial Intelligence · Computer Science 2026-01-06 Albert Sadowski , Jarosław A. Chudziak

Biomedical retrieval-augmented generation (RAG) can ground LLM answers in medical literature, yet long-form outputs often contain isolated unsupported or contradictory claims with safety implications. We introduce MedRAGChecker, a…

Computation and Language · Computer Science 2026-01-13 Yuelyu Ji , Min Gu Kwak , Hang Zhang , Xizhi Wu , Chenyu Li , Yanshan Wang

Syllogistic reasoning is crucial for Natural Language Inference (NLI). This capability is particularly significant in specialized domains such as biomedicine, where it can support automatic evidence interpretation and scientific discovery.…

Computation and Language · Computer Science 2025-02-11 Magdalena Wysocka , Danilo Carvalho , Oskar Wysocki , Marco Valentino , Andre Freitas

In response to the demand for Explainable Artificial Intelligence (XAI), we investigate the use of Large Language Models (LLMs) to transform ML explanations into natural, human-readable narratives. Rather than directly explaining ML models…

Artificial Intelligence · Computer Science 2024-05-13 Alexandra Zytek , Sara Pidò , Kalyan Veeramachaneni

Large Language Models (LLM) have experienced strong development in recent years, with varied applications. This paper uses LLMs to develop a post-hoc process that provides more elaborated explanations of the results of food recommendation…

Information Retrieval · Computer Science 2026-01-07 Melissa Tessa , Diderot D. Cidjeu , Rachele Carli , Sarah Abchiche , Ahmad Aldarwishd , Igor Tchappi , Amro Najjar

This paper investigates the reliability of explanations generated by large language models (LLMs) when prompted to explain their previous output. We evaluate two kinds of such self-explanations - extractive and counterfactual - using three…

Computation and Language · Computer Science 2025-02-03 Korbinian Randl , John Pavlopoulos , Aron Henriksson , Tony Lindgren

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

Machine Learning · Computer Science 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

Accurate disease prediction is vital for timely intervention, effective treatment, and reducing medical complications. While symbolic AI has been applied in healthcare, its adoption remains limited due to the effort required for…

Artificial Intelligence · Computer Science 2026-01-01 Ioanna Gemou , Evangelos Lamprou

Recent reports claim that Large Language Models (LLMs) have achieved the ability to derive new science and exhibit human-level general intelligence. We argue that such claims are not rigorous scientific claims, as they do not satisfy…

Computers and Society · Computer Science 2026-02-11 Elchanan Mossel

Large Language Models (LLMs) are at the forefront of NLP achievements but fall short in dealing with shortcut learning, factual inconsistency, and vulnerability to adversarial inputs.These shortcomings are especially critical in medical…

Computation and Language · Computer Science 2024-04-09 Mael Jullien , Marco Valentino , André Freitas

With the increasing use of large language models (LLMs) for generating answers to biomedical questions, it is crucial to evaluate the quality of the generated answers and the references provided to support the facts in the generated…

Computation and Language · Computer Science 2026-02-10 Deepak Gupta , Davis Bartels , Dina Demner-Fushman

Our society is facing rampant misinformation harming public health and trust. To address the societal challenge, we introduce FACT-GPT, a system leveraging Large Language Models (LLMs) to automate the claim matching stage of fact-checking.…

Computation and Language · Computer Science 2024-02-09 Eun Cheol Choi , Emilio Ferrara

Large language models (LLMs) have grown in their usage to provide support for question answering across numerous disciplines. The models on their own have already shown promise for answering basic questions, however fail quickly where…

Information Retrieval · Computer Science 2025-04-15 David Brett , Anniek Myatt

Ensuring complex systems meet regulations typically requires checking the validity of assurance cases through a claim-argument-evidence framework. Some challenges in this process include the complicated nature of legal and technical texts,…

Computation and Language · Computer Science 2025-07-04 Fariz Ikhwantri , Dusica Marijan

Artificial Intelligence (AI) models increasingly drive high-stakes consumer interactions, yet their decision logic often remains opaque. Prevailing explainable AI techniques rely on post hoc numerical feature attributions, which fail to…

Computation and Language · Computer Science 2026-01-09 Xiang Cheng , Wen Wang , Anindya Ghose