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The technology to generate Spatially Resolved Transcriptomics (SRT) data is rapidly being improved and applied to investigate a variety of biological tissues. The ability to interrogate how spatially localised gene expression can lend new…

Quantitative Methods · Quantitative Biology 2021-08-04 Natalie Charitakis , Mirana Ramialison , Hieu T. Nim

Brain metastasis segmentation in MRI remains a formidable challenge due to diminutive lesion sizes (5-15 mm) and extreme class imbalance (less than 2% tumor volume). While soft-attention CNNs are widely used, we identify a critical failure…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Rowzatul Zannath Prerona

Low-light image enhancement aims to restore the visibility of images captured by visual sensors in dim environments by addressing their inherent signal degradations, such as luminance attenuation and structural corruption. Although numerous…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Yicui Shi , Yuhan Chen , Xiangfei Huang , Zhenguo Wang , Wenxuan Yu , Ying Fang

Early detection and accurate diagnosis can predict the risk of malignant disease transformation, thereby increasing the probability of effective treatment. Identifying mild syndrome with small pathological regions serves as an ominous…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Wei Dai , Rui Liu , Zixuan Wu , Tianyi Wu , Min Wang , Junxian Zhou , Yixuan Yuan , Jun Liu

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang

With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…

Genomics · Quantitative Biology 2024-08-14 Donghai Fang , Fangfang Zhu , Dongting Xie , Wenwen Min

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

Breast ultrasound imaging is a valuable tool for early breast cancer detection, but automated tumor segmentation is challenging due to inherent noise, variations in scale of lesions, and fuzzy boundaries. To address these challenges, we…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Muhammad Azeem Aslam , Asim Naveed , Nisar Ahmed

In this paper, we propose a multi-resolution deep-learning architecture to semantically segment dense large-scale pointclouds. Dense pointcloud data require a computationally expensive feature encoding process before semantic segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2021-01-25 Liuyue Xie , Tomotake Furuhata , Kenji Shimada

Exploiting fine-grained semantic features on point cloud is still challenging due to its irregular and sparse structure in a non-Euclidean space. Among existing studies, PointNet provides an efficient and promising approach to learn shape…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Can Chen , Luca Zanotti Fragonara , Antonios Tsourdos

Medical image segmentation involves identifying and separating object instances in a medical image to delineate various tissues and structures, a task complicated by the significant variations in size, shape, and density of these features.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Sina Ghorbani Kolahi , Seyed Kamal Chaharsooghi , Toktam Khatibi , Afshin Bozorgpour , Reza Azad , Moein Heidari , Ilker Hacihaliloglu , Dorit Merhof

High spectral resolution imagery of the Earth's surface enables users to monitor changes over time in fine-grained scale, playing an increasingly important role in agriculture, defense, and emergency response. However, most current…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Meiqi Hu , Chen Wu , Liangpei Zhang

The advancement of Spatial Transcriptomics (ST) has facilitated the spatially-aware profiling of gene expressions based on histopathology images. Although ST data offers valuable insights into the micro-environment of tumors, its…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Hongyi Wang , Xiuju Du , Jing Liu , Shuyi Ouyang , Yen-Wei Chen , Lanfen Lin

Scene text image super-resolution has significantly improved the accuracy of scene text recognition. However, many existing methods emphasize performance over efficiency and ignore the practical need for lightweight solutions in deployment…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 LeoWu TomyEnrique , Xiangcheng Du , Kangliang Liu , Han Yuan , Zhao Zhou , Cheng Jin

The task of spatial clustering of transcriptomics data is of paramount importance. It enables the classification of tissue samples into diverse subpopulations of cells, which, in turn, facilitates the analysis of the biological functions of…

Machine Learning · Computer Science 2025-07-29 Mehrad Soltani , Luis Rueda

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Transformer-based methods have demonstrated excellent performance on super-resolution visual tasks, surpassing conventional convolutional neural networks. However, existing work typically restricts self-attention computation to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Shu-Chuan Chu , Zhi-Chao Dou , Jeng-Shyang Pan , Shaowei Weng , Junbao Li

Weak spectral responses in hyperspectral images are often obscured by dominant endmembers and sensor noise, resulting in inaccurate abundance estimation. This paper introduces WS-Net, a deep unmixing framework specifically designed to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Zekun Long , Ali Zia , Guanyiman Fu , Vivien Rolland , Jun Zhou

Transformer architecture has emerged to be successful in a number of natural language processing tasks. However, its applications to medical vision remain largely unexplored. In this study, we present UTNet, a simple yet powerful hybrid…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Yunhe Gao , Mu Zhou , Dimitris Metaxas

Spatial transcriptomics (ST) is a novel technology that enables the observation of gene expression at the resolution of individual spots within pathological tissues. ST quantifies the expression of tens of thousands of genes in a tissue…

Machine Learning · Computer Science 2025-11-25 Kaito Shiku , Kazuya Nishimura , Shinnosuke Matsuo , Yasuhiro Kojima , Ryoma Bise