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Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system performance beyond the limit defined by its optical elements. The FPM technique applies a novel…

Optics · Physics 2014-05-02 Xiaoze Ou , Roarke Horstmeyer , Changhuei Yang , Guoan Zheng

Quality control (QC) of medical images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually at significant time and operator cost. We aim to…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso

Three-dimensional (3D) Ultrasound (US) can facilitate diagnosis, treatment planning, and image-guided therapy. However, current studies rarely provide a comprehensive evaluation of volumetric accuracy and reproducibility, highlighting the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Lewis Howell , Manisha Waterston , Tze Min Wah , James H. Chandler , James R. McLaughlan

We propose UNSURF, a novel uncertainty measure for cortical surface reconstruction of clinical brain MRI scans of any orientation, resolution, and contrast. It relies on the discrepancy between predicted voxel-wise signed distance functions…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Raghav Mehta , Karthik Gopinath , Ben Glocker , Juan Eugenio Iglesias

Accelerated MRI shortens acquisition time by subsampling in the measurement $\kappa$-space. Recovering a high-fidelity anatomical image from subsampled measurements requires close cooperation between two components: (1) a sampler that…

Image and Video Processing · Electrical Eng. & Systems 2022-07-28 Tianwei Yin , Zihui Wu , He Sun , Adrian V. Dalca , Yisong Yue , Katherine L. Bouman

We propose an efficient protocol to fully reconstruct a set of high-fidelity quantum gates. Usually, the efficiency of reconstructing high-fidelity quantum gates is limited by the sampling noise. Our protocol is based on a perturbative…

Quantum Physics · Physics 2021-03-24 Ruyu Yang , Ying Li

Uncertainty quantification (UQ) is a vital step in using mathematical models and simulations to take decisions. The field of cardiac simulation has begun to explore and adopt UQ methods to characterise uncertainty in model inputs and how…

Image reconstruction methods based on deep neural networks have shown outstanding performance, equalling or exceeding the state-of-the-art results of conventional approaches, but often do not provide uncertainty information about the…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Riccardo Barbano , Željko Kereta , Chen Zhang , Andreas Hauptmann , Simon Arridge , Bangti Jin

Efficient and fast reconstruction of anatomical structures plays a crucial role in clinical practice. Minimizing retrieval and processing times not only potentially enhances swift response and decision-making in critical scenarios but also…

Large language Models (LLMs) have achieved significant breakthroughs across diverse domains; however, they can still produce unreliable or misleading outputs. For responsible LLM application, Uncertainty Quantification (UQ) techniques are…

Machine Learning · Computer Science 2026-05-15 Qihao Wen , Jiahao Wang , Yang Nan , Pengfei He , Ravi Tandon , Han Xu

Dynamic Retrieval-Augmented Generation adaptively determines when to retrieve during generation to mitigate hallucinations in large language models (LLMs). However, existing methods rely on model-internal signals (e.g., logits, entropy),…

Computation and Language · Computer Science 2026-05-19 Dehai Min , Kailin Zhang , Tongtong Wu , Lu Cheng

Machine learning (ML) offers promising new approaches to tackle complex problems and has been increasingly adopted in chemical and materials sciences. Broadly speaking, ML models employ generic mathematical functions and attempt to learn…

Materials Science · Physics 2024-08-21 Jin Dai , Santosh Adhikari , Mingjian Wen

Predictive estimation, which comprises model calibration, model prediction, and validation, is a common objective when performing inverse uncertainty quantification (UQ) in diverse scientific applications. These techniques typically require…

Numerical Analysis · Mathematics 2024-07-17 Ningxin Yang , Truong Le , Lidija Zdravković , David M. Potts

Uncertainty Quantification (UQ) is a promising approach to improve model reliability, yet quantifying the uncertainty of Large Language Models (LLMs) is non-trivial. In this work, we establish a connection between the uncertainty of LLMs…

Computation and Language · Computer Science 2025-10-16 Mingda Li , Xinyu Li , Weinan Zhang , Longxuan Ma

Quantifying segmentation uncertainty has become an important issue in medical image analysis due to the inherent ambiguity of anatomical structures and its pathologies. Recently, neural network-based uncertainty quantification methods have…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Marc Gantenbein , Ertunc Erdil , Ender Konukoglu

With applications ranging from metabolomics to histopathology, quantitative phase microscopy (QPM) is a powerful label-free imaging modality. Despite significant advances in fast multiplexed imaging sensors and deep-learning-based inverse…

Existing neural networks are memory-consuming and computationally intensive, making deploying them challenging in resource-constrained environments. However, there are various methods to improve their efficiency. Two such methods are…

Machine Learning · Computer Science 2023-11-10 Anastasiia Prutianova , Alexey Zaytsev , Chung-Kuei Lee , Fengyu Sun , Ivan Koryakovskiy

Quantitative susceptibility mapping (QSM) is a valuable magnetic resonance imaging (MRI) contrast mechanism that has demonstrated broad clinical applications. However, the image reconstruction of QSM is challenging due to its ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Yang Gao , Xuanyu Zhu , Bradford A. Moffat , Rebecca Glarin , Alan H. Wilman , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

We present a novel quantum tomographic reconstruction method based on Bayesian inference via the Kalman filter update equations. The method not only yields the maximum likelihood/optimal Bayesian reconstruction, but also a covariance matrix…

Quantum Physics · Physics 2011-05-13 Koenraad M. R. Audenaert , S. Scheel

Existing medical image restoration (Med-IR) methods are typically modality-specific or degradation-specific, failing to generalize across the heterogeneous degradations encountered in clinical practice. We argue this limitation stems from…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Jiyao Liu , Junzhi Ning , Wanying Qu , Lihao Liu , Chenglong Ma , Junjun He , Ningsheng Xu