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Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

Quantitative Methods · Quantitative Biology 2019-09-27 Po-Ya Hsu

Cortical neurons whose activity is recorded in behavioral experiments has been classified into several types such as stimulus-related neurons, delay-period neurons, and reward-related neurons. Moreover, the population activity of neurons…

Neurons and Cognition · Quantitative Biology 2018-11-27 Takuma Tanaka

Bobkov, Houdr\'e, and the last author [2000] introduced a Poincar\'e-type functional parameter, $\lambda_\infty$, of a graph and related it to connectivity of the graph via Cheeger-type inequalities. A work by the second author,…

Computational Complexity · Computer Science 2022-07-04 Majid Farhadi , Anand Louis , Mohit Singh , Prasad Tetali

Artificial Recurrent Neural Networks (RNNs) are widely used in neuroscience to model the collective activity of neurons during behavioral tasks. The high dimensionality of their parameter and activity spaces, however, often make it…

Dynamical Systems · Mathematics 2025-10-16 Alice Marraffa , Renate Krause , Valerio Mante , George Haller

Here we present DIVE: Data-driven Inference of Vertexwise Evolution. DIVE is an image-based disease progression model with single-vertex resolution, designed to reconstruct long-term patterns of brain pathology from short-term longitudinal…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Razvan V. Marinescu , Arman Eshaghi , Marco Lorenzi , Alexandra L. Young , Neil P. Oxtoby , Sara Garbarino , Sebastian J. Crutch , Daniel C. Alexander

Understanding the operation of biological and artificial networks remains a difficult and important challenge. To identify general principles, researchers are increasingly interested in surveying large collections of networks that are…

Machine Learning · Statistics 2022-01-14 Alex H. Williams , Erin Kunz , Simon Kornblith , Scott W. Linderman

Empirical interpolation method (EIM) is a well-known technique to efficiently approximate parameterized functions. This paper proposes to use EIM algorithm to efficiently reduce the dimension of the training data within supervised machine…

Machine Learning · Computer Science 2023-05-18 Harbir Antil , Madhu Gupta , Randy Price

This paper presents a novel deep learning-based approach named RealDiffFusionNet incorporating Neural Controlled Differential Equations (Neural CDE) - time series models that are robust in handling irregularly sampled data - and multi-head…

Machine Learning · Computer Science 2025-01-07 Aashish Cheruvu , Nathaniel Rigoni

Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…

Soft Condensed Matter · Physics 2024-11-05 Gildardo Martinez , Justin Siu , Steven Dang , Dylan Gage , Emma Kao , Juan Carlos Avila , Ruilin You , Ryan McGorty

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Deep neural networks (DNNs) trained on visual tasks develop feature representations that resemble those in the human visual system. Although DNN-based encoding models can accurately predict brain responses to visual stimuli, they offer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Matthew W. Shinkle , Mark D. Lescroart

Here we demonstrate that the activity of neural ensembles can be quantitatively modeled. We first show that an ensemble dynamical model (EDM) accurately approximates the distribution of voltages and average firing rate per neuron of a…

Neurons and Cognition · Quantitative Biology 2015-09-07 Joaquin Rapela , Mark Kostuk , Peter F. Rowat , Tim Mullen , Edward F. Chang , Kristofer Bouchard

Real-world data usually have high dimensionality and it is important to mitigate the curse of dimensionality. High-dimensional data are usually in a coherent structure and make the data in relatively small true degrees of freedom. There are…

Machine Learning · Computer Science 2021-03-12 Xiang Wang , Xiaoyong Li , Junxing Zhu , Zichen Xu , Kaijun Ren , Weiming Zhang , Xinwang Liu , Kui Yu

Segmentation is an important task in a wide range of computer vision applications, including medical image analysis. Recent years have seen an increase in the complexity of medical image segmentation approaches based on sophisticated…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Tariq M Khan , Syed S. Naqvi , Erik Meijering

Convolutional neural networks (CNNs) have been employed along with Variational Monte Carlo methods for finding the ground state of quantum many-body spin systems with great success. In order to do so, however, a CNN with only linearly many…

Quantum Physics · Physics 2022-10-04 Yilong Ju , Shah Saad Alam , Jonathan Minoff , Fabio Anselmi , Han Pu , Ankit Patel

Common measures of neural representational (dis)similarity are designed to be insensitive to rotations and reflections of the neural activation space. Motivated by the premise that the tuning of individual units may be important, there has…

Machine Learning · Computer Science 2023-11-17 Meenakshi Khosla , Alex H. Williams

Network representation learning, as an approach to learn low dimensional representations of vertices, has attracted considerable research attention recently. It has been proven extremely useful in many machine learning tasks over large…

Machine Learning · Computer Science 2019-06-11 Hao Peng , Jianxin Li , Hao Yan , Qiran Gong , Senzhang Wang , Lin Liu , Lihong Wang , Xiang Ren

During development, the mammalian brain differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the effect of neuronal density on the development of…

Neurons and Cognition · Quantitative Biology 2010-04-14 Michael I. Ham , Vadas Gintautas , Marko A. Rodriguez , Ryan A. Bennett , Cara L. Santa Maria , Luis M. A. Bettencourt

Embedding static graphs in low-dimensional vector spaces plays a key role in network analytics and inference, supporting applications like node classification, link prediction, and graph visualization. However, many real-world networks…

Machine Learning · Computer Science 2021-07-23 Claudio D. T. Barros , Matheus R. F. Mendonça , Alex B. Vieira , Artur Ziviani

Maps of brain microarchitecture are important for understanding neurological function and behavior, including alterations caused by chronic conditions such as neurodegenerative disease. Techniques such as knife-edge scanning microscopy…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Leila Saadatifard , Aryan Mobiny , Pavel Govyadinov , Hien Nguyen , David Mayerich