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In advancing discrete-based computational cancer models towards clinical applications, one faces the dilemma of how to deal with an ever growing amount of biomedical data that ought to be incorporated eventually in one form or another.…

Cell Behavior · Quantitative Biology 2008-06-26 Le Zhang , L. Leon Chen , Thomas S. Deisboeck

Segmentation of brain tumor from magnetic resonance imaging (MRI) is a vital process to improve diagnosis, treatment planning and to study the difference between subjects with tumor and healthy subjects. In this paper, we exploit a…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Mobarakol Islam , V Jeya Maria Jose , Hongliang Ren

Gadolinium-based contrast agents (GBCAs) are central to glioma imaging but raise safety, cost, and accessibility concerns. Predicting contrast enhancement from non-contrast MRI using machine learning (ML) offers a safer alternative, as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Sajad Amiri , Shahram Taeb , Sara Gharibi , Setareh Dehghanfard , Somayeh Sadat Mehrnia , Mehrdad Oveisi , Ilker Hacihaliloglu , Arman Rahmim , Mohammad R. Salmanpour

Neurogliomas are among the most aggressive forms of cancer, presenting considerable challenges in both treatment and monitoring due to their unpredictable biological behavior. Magnetic resonance imaging (MRI) is currently the preferred…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Shenghao Zhu , Yifei Chen , Shuo Jiang , Weihong Chen , Chang Liu , Yuanhan Wang , Xu Chen , Yifan Ke , Feiwei Qin , Changmiao Wang , Zhu Zhu

Every year thousands of patients are diagnosed with a glioma, a type of malignant brain tumor. Physicians use MR images as a key tool in the diagnosis and treatment of these patients. Neural networks show great potential to aid physicians…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Eric Carver , Zhenzhen Dai , Evan Liang , James Snyder , Ning Wen

This study introduces the Hybrid Multi-modal VGG (HM-VGG) model, a cutting-edge deep learning approach for the early diagnosis of glaucoma. The HM-VGG model utilizes an attention mechanism to process Visual Field (VF) data, enabling the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Junliang Du , Yiru Cang , Tong Zhou , Jiacheng Hu , Weijie He

Glioblastoma is profoundly heterogeneous in microstructure and vasculature, which may lead to tumor regional diversity and distinct treatment response. Although successful in tumor sub-region segmentation and survival prediction, radiomics…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Yifan Li , Chao Li , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Glioblastomas are the most aggressive fast-growing primary brain cancer which originate in the glial cells of the brain. Accurate identification of the malignant brain tumor and its sub-regions is still one of the most challenging problems…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Ramy A. Zeineldin , Mohamed E. Karar , Franziska Mathis-Ullrich , Oliver Burgert

Meningioma brain tumour discrimination is challenging as many histological patterns are mixed between the different subtypes. In clinical practice, dominant patterns are investigated for signs of specific meningioma pathology; however the…

Computer Vision and Pattern Recognition · Computer Science 2017-04-19 Omar S. Al-Kadi

Precise molecular subtyping of gliomas, including isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion, directly guides surgical and therapeutic decisions, yet currently relies on invasive tissue sampling. Deep learning on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Han Jang , Junhyeok Lee , Heeseong Eum , Joon Jang , Yoseob Han , Seung Hong Choi , Kyu Sung Choi

Objectives We aimed to evaluate the diagnostic performance of deep learning (DL)-based radiomics models for the noninvasive prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion status in glioma patients using MRI…

Quantitative Methods · Quantitative Biology 2025-08-19 Somayeh Farahani , Marjaneh Hejazi , Mehnaz Tabassum , Antonio Di Ieva , Neda Mahdavifar , Sidong Liu

Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients'…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Daniil Tikhonov , Matheus Scatolin , Mohor Banerjee , Qiankun Ji , Ahmed Jaheen , Mostafa Salem , Abdelrahman Elsayed , Hu Wang , Sarim Hashmi , Mohammad Yaqub

Accurate classification of brain tumors from magnetic resonance imaging (MRI) plays a critical role in early diagnosis and effective treatment planning. In this study, we propose a deep learning framework based on Vision Transformers (ViT)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Faisal Ahmed

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Lijun Yan , Churan Wang , Fangwei Zhong , Yizhou Wang

Glioblastoma is a highly invasive brain tumor with rapid progression rates. Recent studies have shown that glioblastoma molecular subtype classification serves as a significant biomarker for effective targeted therapy selection. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Shekhnaz Idrissova , Islem Rekik

Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterised by distinct combinations of genetic and epigenetic alterations, resulting in complex interactions…

Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma (GBM) patients is crucial for optimal treatment planning. However, this task remains challenging due to the…

Brain tumors are one of the most common diseases that lead to early death if not diagnosed at an early stage. Traditional diagnostic approaches are extremely time-consuming and prone to errors. In this context, computer vision-based…

Computer Vision and Pattern Recognition · Computer Science 2024-07-01 Niful Islam , Mohaiminul Islam Bhuiyan , Jarin Tasnim Raya , Nur Shazwani Kamarudin , Khan Md Hasib , M. F. Mridha , Dewan Md. Farid

Overall survival (OS) time is one of the most important evaluation indices for gliomas situations. Multimodal Magnetic Resonance Imaging (MRI) scans play an important role in the study of glioma prognosis OS time. Several deep…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Wen Tang , Haoyue Zhang , Pengxin Yu , Han Kang , Rongguo Zhang

Early detection of brain tumors through magnetic resonance imaging (MRI) is essential for timely treatment, yet access to diagnostic facilities remains limited in remote areas. Gliomas, the most common primary brain tumors, arise from the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Khush Mendiratta , Shweta Singh , Pratik Chattopadhyay