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Purpose: Delineating tumor boundaries during breast-conserving surgery is challenging as tumors are often highly mobile, non-palpable, and have irregularly shaped borders. To address these challenges, we introduce a cooperative robotic…

Breast cancer investigation is of great significance, and developing tumor detection methodologies is a critical need. However, it is a challenging task for breast ultrasound due to the complicated breast structure and poor quality of the…

Computer Vision and Pattern Recognition · Computer Science 2019-10-24 Fei Xu , Yingtao Zhang , Min Xian , H. D. Cheng , Boyu Zhang , Jianrui Ding , Chunping Ning , Ying Wang

We present first a brief review of the existing literature on shape optimization, stressing the recent use of Hamiltonian systems in topology optimization. In the second section, we collect some preliminaries on the implicit parametrization…

Optimization and Control · Mathematics 2022-11-23 Cornel Marius Murea , Dan Tiba

Brain tumors require an assessment to ensure timely diagnosis and effective patient treatment. Morphological factors such as size, location, texture, and variable appearance complicate tumor inspection. Medical imaging presents challenges,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Md. Zahid Hasan , Abdullah Tamim , D. M. Asadujjaman , Md. Mahfujur Rahman , Md. Abu Ahnaf Mollick , Nosin Anjum Dristi , Abdullah-Al-Noman

We study optimal design problems involving variational inequalities with unilateral conditions in the domain and pointwise boundary observation. We use regularizing and penalization tehniques in the setting of the Hamiltonian approach to…

Optimization and Control · Mathematics 2025-12-30 Cornel Marius Murea , Dan Tiba

Many problems in engineering can be understood as controlling the bifurcation structure of a given device. For example, one may wish to delay the onset of instability, or bring forward a bifurcation to enable rapid switching between states.…

Numerical Analysis · Mathematics 2022-01-24 Nicolas Boullé , Patrick E. Farrell , Alberto Paganini

The inverse geometric approach to the modeling of the growth of circular objects revealing required features, such as the velocity of the growth and fractal behavior of their contours, is presented. It enables to reproduce some of the…

Medical Physics · Physics 2007-05-23 Branislav Brutovsky , Denis Horvath , Vladimir Lisy

Medical image registration is a critical task that estimates the spatial correspondence between pairs of images. However, current traditional and deep-learning-based methods rely on similarity measures to generate a deforming field, which…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Qihua Dong , Hao Du , Ying Song , Yan Xu , Jing Liao

This investigation is motivated by the problem of optimal design of cooling elements in modern battery systems. We consider a simple model of two-dimensional steady-state heat conduction described by elliptic partial differential equations…

Numerical Analysis · Mathematics 2013-07-05 Xiaohui Peng , Katsiaryna Niakhai , Bartosz Protas

In this paper we present a method for estimating unknown parameter that appear on a non-linear reaction-diffusion model of cancer invasion. This model considers that tumor-induced alteration of micro-enviromental pH provides a mechanism for…

Optimization and Control · Mathematics 2014-01-14 Andrés Quiroga , Damián Fernández , Germán Torres , Cristina Turner

In the study of high-dimensional data, it is often assumed that the data set possesses an underlying lower-dimensional structure. A practical model for this structure is an embedded compact manifold with boundary. Since the underlying…

Machine Learning · Statistics 2025-08-22 Pei-Cheng Kuo , Nan Wu

We consider a one--spatial dimensional tumour growth model [2, 3, 4] that consists of three dependent variables of space and time: volume fraction of tumour cells, velocity of tumour cells, and nutrient concentration. The model variables…

Numerical Analysis · Mathematics 2020-07-01 Jerome Droniou , Neela Nataraj , Gopikrishnan Chirappurathu Remesan

We demonstrate identification of position, material, orientation and shape of objects imaged by an $^{85}$Rb atomic magnetometer performing electromagnetic induction imaging supported by machine learning. Machine learning maximizes the…

Atomic Physics · Physics 2018-01-24 Cameron Deans , Lewis D. Griffin , Luca Marmugi , Ferruccio Renzoni

This article proposes a new discrete framework for approximating solutions to shape optimization problems under convexity constraints. The numerical method, based on the support function or the gauge function, is guaranteed to generate…

Optimization and Control · Mathematics 2022-03-15 Beniamin Bogosel

We present a general numerical approach to shape optimization with state constraints for 2-dimensional geometries, without relaxing the constraints. To do this we reformulate the problem on a fixed reference domain using a conformal…

Optimization and Control · Mathematics 2014-12-16 Christian Leithäuser , René Pinnau , Robert Feßler

We propose a novel Riemannian method for solving the Extreme multi-label classification problem that exploits the geometric structure of the sparse low-dimensional local embedding models. A constrained optimization problem is formulated as…

Optimization and Control · Mathematics 2021-10-01 Jayadev Naram , Tanmay Kumar Sinha , Pawan Kumar

Intra-tumor heterogeneity driving disease progression is characterized by distinct growth and spatial proliferation patterns of cells and their nuclei within tumor and non-tumor tissues. A widely accepted hypothesis is that these spatial…

Applications · Statistics 2025-11-13 Ye Jin Choi , Sebastian Kurtek , Simeng Zhu , Karthik Bharath

A new method for numerical solving of boundary problem for ordinary differential equations with slowly varying coefficients which is aimed at better representation of solutions in the regions of their rapid oscillations or exponential…

Computational Physics · Physics 2007-05-23 V. E. Moiseenko , V. V. Pilipenko

Semantic segmentation of brain tumours is a fundamental task in medical image analysis that can help clinicians in diagnosing the patient and tracking the progression of any malignant entities. Accurate segmentation of brain lesions is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Aditya Kasliwal , Sankarshanaa Sagaram , Laven Srivastava , Pratinav Seth , Adil Khan

In this paper, we tackle the problem of reconstructing earlier tumour configurations starting from a single spatial measurement at a later time. We describe the tumour evolution through a diffuse interface model coupling a…

Analysis of PDEs · Mathematics 2024-09-25 Abramo Agosti , Elena Beretta , Cecilia Cavaterra , Matteo Fornoni , Elisabetta Rocca