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Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Cheng Ouyang , Chen Chen , Surui Li , Zeju Li , Chen Qin , Wenjia Bai , Daniel Rueckert

Deep learning models in medical image analysis often struggle with generalizability across domains and demographic groups due to data heterogeneity and scarcity. Traditional augmentation improves robustness, but fails under substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Sebastian Doerrich , Francesco Di Salvo , Jonas Alle , Christian Ledig

Domain generalizable model is attracting increasing attention in medical image analysis since data is commonly acquired from different institutes with various imaging protocols and scanners. To tackle this challenging domain generalization…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Ran Gu , Jingyang Zhang , Rui Huang , Wenhui Lei , Guotai Wang , Shaoting Zhang

Medical image segmentation plays an important role in clinical decision making, treatment planning, and disease tracking. However, it still faces two major challenges. On the one hand, there is often a ``soft boundary'' between foreground…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Mengqi Lei , Haochen Wu , Xinhua Lv , Xin Wang

The task of single-source domain generalization (SDG) in medical image segmentation is crucial due to frequent domain shifts in clinical image datasets. To address the challenge of poor generalization across different domains, we introduce…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Haoyu Zhao , Wenhui Dong , Rui Yu , Zhou Zhao , Du Bo , Yongchao Xu

As the leading cause of death worldwide, cardiovascular diseases motivate the development of more sophisticated methods to analyze the heart and its substructures from medical images like Computed Tomography (CT) and Magnetic Resonance…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Franz Thaler , Darko Stern , Gernot Plank , Martin Urschler

Tackling domain shifts in multi-centre and multi-vendor data sets remains challenging for cardiac image segmentation. In this paper, we propose a generalisable segmentation framework for cardiac image segmentation in which multi-centre,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Hongwei Li , Jianguo Zhang , Bjoern Menze

Contemporary methods have shown promising results on cardiac image segmentation, but merely in static learning, i.e., optimizing the network once for all, ignoring potential needs for model updating. In real-world scenarios, new data…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Kang Li , Lequan Yu , Pheng-Ann Heng

This paper presents a novel unsupervised domain adaptation framework, called Synergistic Image and Feature Adaptation (SIFA), to effectively tackle the problem of domain shift. Domain adaptation has become an important and hot topic in…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Cheng Chen , Qi Dou , Hao Chen , Jing Qin , Pheng-Ann Heng

Domain Generalization (DG) aims to reduce domain shifts between domains to achieve promising performance on the unseen target domain, which has been widely practiced in medical image segmentation. Single-source domain generalization (SDG)…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Hanhui Wang , Huaize Ye , Yi Xia , Xueyan Zhang

Domain generalization typically requires data from multiple source domains for model learning. However, such strong assumption may not always hold in practice, especially in medical field where the data sharing is highly concerned and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Quande Liu , Cheng Chen , Qi Dou , Pheng-Ann Heng

Deep learning-based medical image segmentation faces significant challenges arising from limited labeled data and domain shifts. While prior approaches have primarily addressed these issues independently, their simultaneous occurrence is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zanting Ye , Ke Wang , Wenbing Lv , Qianjin Feng , Lijun Lu

The annotation scarcity of medical image segmentation poses challenges in collecting sufficient training data for deep learning models. Specifically, models trained on limited data may not generalize well to other unseen data domains,…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Heng Li , Haojin Li , Wei Zhao , Huazhu Fu , Xiuyun Su , Yan Hu , Jiang Liu

Single-source domain generalization (SDG) in medical image segmentation remains a significant challenge, particularly for images with varying color distributions and qualities. Previous approaches often struggle when models trained on…

Image and Video Processing · Electrical Eng. & Systems 2025-02-12 Ravi Shah , Atsushi Fukuda , Quan Huu Cap

We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

Retinal vascular morphology is crucial for diagnosing diseases such as diabetes, glaucoma, and hypertension, making accurate segmentation of retinal vessels essential for early intervention. Traditional segmentation methods assume that…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Bo Liu , Yudong Zhang , Shuihua Wang , Siyue Li , Jin Hong

Domain generalization is a technique aimed at enabling models to maintain high accuracy when applied to new environments or datasets (unseen domains) that differ from the datasets used in training. Generally, the accuracy of models trained…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Reiji Saito , Kazuhiro Hotta

Deep learning models for medical image segmentation often struggle when deployed across different datasets due to domain shifts - variations in both image appearance, known as style, and population-dependent anatomical characteristics,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Hoda Kalabizadeh , Ludovica Griffanti , Pak-Hei Yeung , Ana I. L. Namburete , Nicola K. Dinsdale , Konstantinos Kamnitsas

Domain Adaptation is a technique to address the lack of massive amounts of labeled data in unseen environments. Unsupervised domain adaptation is proposed to adapt a model to new modalities using solely labeled source data and unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Thong Vo , Naimul Khan

In medical image segmentation, domain generalization poses a significant challenge due to domain shifts caused by variations in data acquisition devices and other factors. These shifts are particularly pronounced in the most common…

Computer Vision and Pattern Recognition · Computer Science 2023-11-06 Ruxue Wen , Hangjie Yuan , Dong Ni , Wenbo Xiao , Yaoyao Wu