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The absence of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. Although various methods of explainable artificial intelligence (XAI) have been suggested, there is a lack of literature that…

Machine Learning · Computer Science 2023-06-22 Aida Brankovic , David Cook , Jessica Rahman , Wenjie Huang , Sankalp Khanna

Explainable artificial intelligence (XAI) is essential for enabling clinical users to get informed decision support from AI and comply with evidence-based medical practice. Applying XAI in clinical settings requires proper evaluation…

Machine Learning · Computer Science 2022-12-09 Weina Jin , Xiaoxiao Li , Mostafa Fatehi , Ghassan Hamarneh

XAI refers to the techniques and methods for building AI applications which assist end users to interpret output and predictions of AI models. Black box AI applications in high-stakes decision-making situations, such as medical domain have…

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

Artificial Intelligence · Computer Science 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

Given the sheer volume of surgical procedures and the significant rate of postoperative fatalities, assessing and managing surgical complications has become a critical public health concern. Existing artificial intelligence (AI) tools for…

Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques…

Machine Learning · Computer Science 2022-09-15 Flavio Di Martino , Franca Delmastro

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Explainable Artificial Intelligence (XAI) is essential for building advanced machine learning-powered applications, especially in critical domains such as medical diagnostics or autonomous driving. Legal, business, and ethical requirements…

Human-Computer Interaction · Computer Science 2024-10-17 Tobias Labarta , Elizaveta Kulicheva , Ronja Froelian , Christian Geißler , Xenia Melman , Julian von Klitzing

The lack of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. While explainable artificial intelligence (XAI) methods have been proposed, little research has focused on the agreement between…

Machine Learning · Computer Science 2023-11-29 Aida Brankovic , Wenjie Huang , David Cook , Sankalp Khanna , Konstanty Bialkowski

Explainable AI (XAI) holds the promise of advancing the implementation and adoption of AI-based tools in practice, especially in high-stakes environments like healthcare. However, most of the current research lacks input from end users, and…

Machine Learning · Computer Science 2025-08-06 T. E. Röber , R. Goedhart , S. İ. Birbil

Despite promising developments in Explainable Artificial Intelligence, the practical value of XAI methods remains under-explored and insufficiently validated in real-world settings. Robust and context-aware evaluation is essential, not only…

Human-Computer Interaction · Computer Science 2025-06-18 Ivania Donoso-Guzmán , Kristýna Sirka Kacafírková , Maxwell Szymanski , An Jacobs , Denis Parra , Katrien Verbert

Explainable Artificial Intelligence (XAI) is a rising field in AI. It aims to produce a demonstrative factor of trust, which for human subjects is achieved through communicative means, which Machine Learning (ML) algorithms cannot solely…

Machine Learning · Computer Science 2021-03-09 Jamie Andrew Duell

Explainable AI (XAI) is widely viewed as a sine qua non for ever-expanding AI research. A better understanding of the needs of XAI users, as well as human-centered evaluations of explainable models are both a necessity and a challenge. In…

Artificial Intelligence · Computer Science 2024-10-17 Yao Rong , Tobias Leemann , Thai-trang Nguyen , Lisa Fiedler , Peizhu Qian , Vaibhav Unhelkar , Tina Seidel , Gjergji Kasneci , Enkelejda Kasneci

The complex nature of disease mechanisms and the variability of patient symptoms pose significant challenges in developing effective diagnostic tools. Although machine learning (ML) has made substantial advances in medical diagnosis, the…

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Bas H. M. van der Velden , Hugo J. Kuijf , Kenneth G. A. Gilhuijs , Max A. Viergever

Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining…

Artificial intelligence (AI) models are increasingly finding applications in the field of medicine. Concerns have been raised about the explainability of the decisions that are made by these AI models. In this article, we give a systematic…

Machine Learning · Computer Science 2023-04-12 Subrato Bharati , M. Rubaiyat Hossain Mondal , Prajoy Podder

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Artificial intelligence models encounter significant challenges due to their black-box nature, particularly in safety-critical domains such as healthcare, finance, and autonomous vehicles. Explainable Artificial Intelligence (XAI) addresses…

Artificial Intelligence · Computer Science 2025-03-14 Melkamu Mersha , Khang Lam , Joseph Wood , Ali AlShami , Jugal Kalita
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