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The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

Large language model (LLM)-based recommender models that bridge users and items through textual prompts for effective semantic reasoning have gained considerable attention. However, few methods consider the underlying rationales behind…

Computation and Language · Computer Science 2025-01-09 Xinfeng Wang , Jin Cui , Yoshimi Suzuki , Fumiyo Fukumoto

Generating user-friendly explanations regarding why an item is recommended has become increasingly common, largely due to advances in language generation technology, which can enhance user trust and facilitate more informed decision-making…

Information Retrieval · Computer Science 2024-01-04 Yucong Luo , Mingyue Cheng , Hao Zhang , Junyu Lu , Qi Liu , Enhong Chen

Owing to their powerful semantic reasoning capabilities, Large Language Models (LLMs) have been effectively utilized as recommenders, achieving impressive performance. However, the high inference latency of LLMs significantly restricts…

Information Retrieval · Computer Science 2024-08-21 Yu Cui , Feng Liu , Pengbo Wang , Bohao Wang , Heng Tang , Yi Wan , Jun Wang , Jiawei Chen

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

In recent years, large language models (LLM) have emerged as powerful tools for diverse natural language processing tasks. However, their potential for recommender systems under the generative recommendation paradigm remains relatively…

Information Retrieval · Computer Science 2023-07-11 Jianchao Ji , Zelong Li , Shuyuan Xu , Wenyue Hua , Yingqiang Ge , Juntao Tan , Yongfeng Zhang

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

Computation and Language · Computer Science 2024-07-16 Yu-Tzu Lee

Molecule generation and optimization is a fundamental task in chemical domain. The rapid development of intelligent tools, especially large language models (LLMs) with powerful knowledge reserves and interactive capabilities, has provided…

Machine Learning · Computer Science 2026-02-10 Haoran Liu , Zheni Zeng , Yukun Yan , Yuxuan Chen , Yunduo Xiao

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Explainable disease diagnosis, which leverages patient information (e.g., signs and symptoms) and computational models to generate probable diagnoses and reasonings, offers clear clinical values. However, when clinical notes encompass…

Recommendation systems are widely used in e-commerce websites and online platforms to address information overload. However, existing systems primarily rely on historical data and user feedback, making it difficult to capture user intent…

Information Retrieval · Computer Science 2024-02-22 Qian Zhao , Hao Qian , Ziqi Liu , Gong-Duo Zhang , Lihong Gu

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Large language models (LLMs), such as GPT-4, have demonstrated remarkable capabilities across a wide range of tasks, including health applications. In this paper, we study how LLMs can be used to scale biomedical knowledge curation. We find…

Large language models (LLMs) have demonstrated exceptional performance in understanding and generating semantic patterns, making them promising candidates for sequential recommendation tasks. However, when combined with conventional…

Information Retrieval · Computer Science 2025-05-26 Jiongran Wu , Jiahao Liu , Dongsheng Li , Guangping Zhang , Mingzhe Han , Hansu Gu , Peng Zhang , Li Shang , Tun Lu , Ning Gu

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Large language models have become increasingly popular and demonstrated remarkable performance in various natural language processing (NLP) tasks. However, these models are typically computationally expensive and difficult to be deployed in…

Computation and Language · Computer Science 2024-09-20 Dongheng Li , Yongchang Hao , Lili Mou
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