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In addition to evaluating tumor morphology using H&E staining, immunohistochemistry is used to assess the presence of specific proteins within the tissue. However, this is a costly and labor-intensive technique, for which virtual staining,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 José Teixeira , Pascal Klöckner , Diana Montezuma , Melis Erdal Cesur , João Fraga , Hugo M. Horlings , Jaime S. Cardoso , Sara P. Oliveira

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

Understanding the way cells communicate, co-locate, and interrelate is essential to furthering our understanding of how the body functions. H&E is widely available, however, cell subtyping often requires expert knowledge and the use of…

Conventional hematoxylin-eosin (H&E) staining is limited to revealing cell morphology and distribution, whereas immunohistochemical (IHC) staining provides precise and specific visualization of protein activation at the molecular level.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Fuqiang Chen , Ranran Zhang , Boyun Zheng , Yiwen Sun , Jiahui He , Wenjian Qin

Foundation models for medical image segmentation have achieved remarkable performance. Adaptive fine-tuning of natural image segmentation foundation models is crucial for medical image segmentation tasks. However, some limitations exist in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Xinwei Zhang , Hu Chen , Zhe Yuan , Sukun Tian , Peng Feng

Deep learning has gained significant attention in medical image segmentation. However, the limited availability of annotated training data presents a challenge to achieving accurate results. In efforts to overcome this challenge, data…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Skin detection is one of the most important and primary stages in some of image processing applications such as face detection and human tracking. So far, many approaches are proposed to done this case. Near all of these methods have tried…

Computer Vision and Pattern Recognition · Computer Science 2014-07-25 Reza Azad , Hamid Reza Shayegh

The integration of quantum machine learning with classical deep learning offers promising avenues for medical image analysis by mapping data into high-dimensional Hilbert spaces. However, effectively unifying these distinct paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yasmin Rodrigues Sobrinho , João Renato Ribeiro Manesco , João Paulo Papa

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

As an ever-increasing demand for high dynamic range (HDR) scene shooting, multi-exposure image fusion (MEF) technology has abounded. In recent years, multi-scale exposure fusion approaches based on detail-enhancement have led the way for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Xiaoning Liu

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Recent years have witnessed an increased interest in image dehazing. Many deep learning methods have been proposed to tackle this challenge, and have made significant accomplishments dealing with homogeneous haze. However, these solutions…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Yangyi Liu , Huan Liu , Liangyan Li , Zijun Wu , Jun Chen

Hyperspectral image (HSI) fusion addresses the challenge of reconstructing High-Resolution HSIs (HR-HSIs) from High-Resolution Multispectral images (HR-MSIs) and Low-Resolution HSIs (LR-HSIs), a critical task given the high costs and…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Chia-Ming Lee , Yu-Fan Lin , Yu-Hao Ho , Li-Wei Kang , Chih-Chung Hsu

Feature selection is a combinatorial optimization problem that is NP-hard. Conventional approaches often employ heuristic or greedy strategies, which are prone to premature convergence and may fail to capture subtle yet informative…

Machine Learning · Computer Science 2025-10-22 Yusi Fan , Tian Wang , Zhiying Yan , Chang Liu , Qiong Zhou , Qi Lu , Zhehao Guo , Ziqi Deng , Wenyu Zhu , Ruochi Zhang , Fengfeng Zhou

Histopathology image segmentation is the gold standard for diagnosing cancer, and can indicate cancer prognosis. However, histopathology image segmentation requires high-quality masks, so many studies now use imagelevel labels to achieve…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Liangrui Pan , Lian Wang , Zhichao Feng , Liwen Xu , Shaoliang Peng

Hematoxylin and Eosin (H&E) staining is the cornerstone of histopathology but lacks molecular specificity. While Immunohistochemistry (IHC) provides molecular insights, it is costly and complex, motivating H&E-to-IHC translation as a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Erik Großkopf , Valay Bundele , Mehran Hosseinzadeh , Hendrik P. A. Lensch

Despite advancements in methodologies, immunohistochemistry (IHC) remains the most utilized ancillary test for histopathologic and companion diagnostics in targeted therapies. However, objective IHC assessment poses challenges. Artificial…

Histopathology image analysis is fundamental to digital pathology, with hematoxylin and eosin (H&E) staining as the gold standard for diagnostic and prognostic assessments. While H&E imaging effectively highlights cellular and tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Yao Du , Jiaxin Zhuang , Xiaoyu Zheng , Jing Cong , Limei Guo , Chao He , Lin Luo , Xiaomeng Li

Recent advances in large-scale text-to-image generation models have led to a surge in subject-driven text-to-image generation, which aims to produce customized images that align with textual descriptions while preserving the identity of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Kewen Chen , Xiaobin Hu , Wenqi Ren
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