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Despite the state-of-the-art performance for medical image segmentation, deep convolutional neural networks (CNNs) have rarely provided uncertainty estimations regarding their segmentation outputs, e.g., model (epistemic) and image-based…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Guotai Wang , Wenqi Li , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

In this paper, we introduce the first diffusion model designed to generate complete synthetic human genotypes, which, by standard protocols, one can straightforwardly expand into full-length, DNA-level genomes. The synthetic genotypes mimic…

Computational Engineering, Finance, and Science · Computer Science 2025-01-31 Philip Kenneweg , Raghuram Dandinasivara , Xiao Luo , Barbara Hammer , Alexander Schönhuth

Diffusion Probabilistic Methods are employed for state-of-the-art image generation. In this work, we present a method for extending such models for performing image segmentation. The method learns end-to-end, without relying on a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Tomer Amit , Tal Shaharbany , Eliya Nachmani , Lior Wolf

The lack of real-world data in clinical fields poses a major obstacle in training effective AI models for diagnostic and preventive tools in medicine. Generative AI has shown promise in increasing data volume and enhancing model training,…

Machine Learning · Computer Science 2026-02-10 Md Shahriar Kabir , Sana Alamgeer , Minakshi Debnath , Anne H. H. Ngu

Deep learning models with large learning capacities often overfit to medical imaging datasets. This is because training sets are often relatively small due to the significant time and financial costs incurred in medical data acquisition and…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Lok Hin Lee , Yuan Gao , J. Alison Noble

Robot-guided catheter insertion has the potential to deliver urgent medical care in situations where medical personnel are unavailable. However, this technique requires accurate and reliable segmentation of anatomical landmarks in the body.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-19 Cecilia Morales , Jason Yao , Tejas Rane , Robert Edman , Howie Choset , Artur Dubrawski

Long-tailed class distributions are pervasive in multi-class medical datasets and pose significant challenges for deep learning models which typically underperform on tail classes with limited samples. This limitation is particularly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Jiaxiang Jiang , Mahesh Subedar , Omesh Tickoo

Foundational models have emerged as powerful tools for addressing various tasks in clinical settings. However, their potential development to breast ultrasound analysis remains untapped. In this paper, we present BUSGen, the first…

With the development of audio playback devices and fast data transmission, the demand for high sound quality is rising for both entertainment and communications. In this quest for better sound quality, challenges emerge from distortions and…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-12 Jean-Marie Lemercier , Julius Richter , Simon Welker , Eloi Moliner , Vesa Välimäki , Timo Gerkmann

Identifying model parameters from observed configurations poses a fundamental challenge in data science, especially with limited data. Recently, diffusion models have emerged as a novel paradigm in generative machine learning, capable of…

Data Analysis, Statistics and Probability · Physics 2025-03-14 Yechan Lim , Sangwon Lee , Junghyo Jo

Purpose: Bone metastasis have a major impact on the quality of life of patients and they are diverse in terms of size and location, making their segmentation complex. Manual segmentation is time-consuming, and expert segmentations are…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Emile Saillard , Aurélie Levillain , David Mitton , Jean-Baptiste Pialat , Cyrille Confavreux , Hélène Follet , Thomas Grenier

Segmentation of enhancement in LGE cardiac MRI is critical for diagnosing various ischemic and non-ischemic cardiomyopathies. However, creating pixel-level annotations for these images is challenging and labor-intensive, leading to limited…

Artificial Intelligence · Computer Science 2026-03-20 Athira J. Jacob , Puneet Sharma , Daniel Rueckert

Diffusion generative models transform noise into data by inverting a process that progressively adds noise to data samples. Inspired by concepts from the renormalization group in physics, which analyzes systems across different scales, we…

Machine Learning · Computer Science 2024-10-04 Mathis Gerdes , Max Welling , Miranda C. N. Cheng

Medical image analysis suffers from a lack of labeled data due to several challenges including patient privacy and lack of experts. Although some AI models only perform well with large amounts of data, we will move to data augmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Khadija Rais , Mohamed Amroune , Mohamed Yassine Haouam , Abdelmadjid Benmachiche

Generative diffusion models have emerged as leading models in speech and image generation. However, in order to perform well with a small number of denoising steps, a costly tuning of the set of noise parameters is needed. In this work, we…

Machine Learning · Computer Science 2021-09-14 Robin San-Roman , Eliya Nachmani , Lior Wolf

Training supervised deep neural networks that perform defect detection and segmentation requires large-scale fully-annotated datasets, which can be hard or even impossible to obtain in industrial environments. Generative AI offers…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Gabriele Valvano , Antonino Agostino , Giovanni De Magistris , Antonino Graziano , Giacomo Veneri

Reliable machine learning and statistical analysis rely on diverse, well-distributed training data. However, real-world datasets are often limited in size and exhibit underrepresentation across key subpopulations, leading to biased…

Methodology · Statistics 2025-07-15 Xinyu Tian , Xiaotong Shen

We introduce a framework for joint grounded scene graph - image generation, a challenging task involving high-dimensional, multi-modal structured data. To effectively model this complex joint distribution, we adopt a factorized approach:…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Bicheng Xu , Qi Yan , Renjie Liao , Lele Wang , Leonid Sigal

Medical image segmentation often involves inherent uncertainty due to variations in expert annotations. Capturing this uncertainty is an important goal and previous works have used various generative image models for the purpose of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Jakob Lønborg Christensen , Morten Rieger Hannemose , Anders Bjorholm Dahl , Vedrana Andersen Dahl

Three-dimensional ultrasound enables real-time volumetric visualization of anatomical structures. Unlike traditional 2D ultrasound, 3D imaging reduces reliance on precise probe orientation, potentially making ultrasound more accessible to…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Tristan S. W. Stevens , Oisín Nolan , Oudom Somphone , Jean-Luc Robert , Ruud J. G. van Sloun