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Related papers: PhenoProfiler: Advancing Phenotypic Learning for I…

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Early diagnosis of melanoma, which can save thousands of lives, relies heavily on the analysis of dermoscopic images. One crucial diagnostic criterion is the identification of unusual pigment network (PN). However, distinguishing between…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 M. A. Rasel , Sameem Abdul Kareem , Unaizah Obaidellah

Recent breakthroughs by deep neural networks (DNNs) in natural language processing (NLP) and computer vision have been driven by a scale-up of models and data rather than the discovery of novel computing paradigms. Here, we investigate if…

Phenomics is an emerging branch of modern biology that uses high throughput phenotyping tools to capture multiple environmental and phenotypic traits, often at massive spatial and temporal scales. The resulting high dimensional data…

Quantitative Methods · Quantitative Biology 2019-06-06 Methun Kamruzzaman , Ananth Kalyanaraman , Bala Krishnamoorthy , Stefan Hey , Patrick Schnable

Being accurate, efficient, and compact is essential to a facial landmark detector for practical use. To simultaneously consider the three concerns, this paper investigates a neat model with promising detection accuracy under wild…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Xiaojie Guo , Siyuan Li , Jinke Yu , Jiawan Zhang , Jiayi Ma , Lin Ma , Wei Liu , Haibin Ling

Identifying predictive covariates, which forecast individual treatment effectiveness, is crucial for decision-making across different disciplines such as personalized medicine. These covariates, referred to as biomarkers, are extracted from…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Shuhan Xiao , Lukas Klein , Jens Petersen , Philipp Vollmuth , Paul F. Jaeger , Klaus H. Maier-Hein

In this study, we propose HOPER (HOlistic ProtEin Representation), a novel multimodal learning framework designed to enhance protein function prediction (PFP) in low-data settings. The challenge of predicting protein functions is compounded…

Biomolecules · Quantitative Biology 2024-12-18 Serbülent Ünsal , Sinem Özdemir , Bünyamin Kasap , M. Erşan Kalaycı , Kemal Turhan , Tunca Doğan , Aybar C. Acar

As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Maxim Sharaev , Alexander Andreev , Alexey Artemov , Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Renat Akzhigitov

A major goal of neuroscience is to understand brain computations during visual processing in naturalistic settings. A dominant approach is to use image-computable deep neural networks trained with different task objectives as a basis for…

Neurons and Cognition · Quantitative Biology 2026-02-06 Hossein Adeli , Sun Minni , Nikolaus Kriegeskorte

Nowadays, the adoption of face recognition for biometric authentication systems is usual, mainly because this is one of the most accessible biometric modalities. Techniques that rely on trespassing these kind of systems by using a forged…

Computer Vision and Pattern Recognition · Computer Science 2019-02-11 Rodrigo Bresan , Allan Pinto , Anderson Rocha , Carlos Beluzo , Tiago Carvalho

Parameter-efficient transfer learning (PETL) is a promising task, aiming to adapt the large-scale pre-trained model to downstream tasks with a relatively modest cost. However, current PETL methods struggle in compressing computational…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Yurong Zhang , Honghao Chen , Xinyu Zhang , Xiangxiang Chu , Li Song

Accurate segmentation of organs and lesions in medical images is essential for clinical applications including diagnosis, prognosis, and treatment planning. While Vision Transformers (ViTs) have shown impressive segmentation performance,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jin Yang , Xiaobing Yu , Peijie Qiu

Imaging-derived phenotypes (IDPs) summarize multi-organ physiology but provide only static snapshots of diseases that evolve over time. In contrast, longitudinal electronic health records encode disease trajectories through temporal…

Information Retrieval · Computer Science 2026-05-13 Zian Wang , Lizhen Lan , Guangming Wang , Haosen Zhang , Minxuan Xu , Qing Li , Tianxing He , Mo Yang , Wenyue Mao , Yajing Zhang , Yan Li , Chengyan Wang

We present a complete system for real-time rendering of scenes with complex appearance previously reserved for offline use. This is achieved with a combination of algorithmic and system level innovations. Our appearance model utilizes…

Predicting the response of a cancer cell line to a therapeutic drug is pivotal for personalized medicine. Despite numerous deep learning methods that have been developed for drug response prediction, integrating diverse information about…

Machine Learning · Computer Science 2025-03-31 Haoyuan Shi , Tao Xu , Xiaodi Li , Qian Gao , Zhiwei Xiong , Junfeng Xia , Zhenyu Yue

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Connecting the dynamics of biomolecular networks to experimentally measurable cell phenotypes remains a central challenge in systems biology. Here we introduce a model-based definition of phenotype as a partial steady state that is…

Molecular Networks · Quantitative Biology 2026-02-18 Samuel Pastva , Kyu Hyong Park , Jordan C. Rozum , Van-Giang Trinh , Réka Albert

Liquid chromatography with tandem mass spectrometry (LC-MS/MS) based proteomics is a well-established research field with major applications such as identification of disease biomarkers, drug discovery, drug design and development. In…

Quantitative Methods · Quantitative Biology 2018-01-08 Fatema Tuz Zohora , Ngoc Hieu Tran , Xianglilan Zhang , Lei Xin , Baozhen Shan , Ming Li

In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Valentin Koch , Sophia J. Wagner , Salome Kazeminia , Ece Sancar , Matthias Hehr , Julia Schnabel , Tingying Peng , Carsten Marr

One of the grand challenges of utilizing machine learning for the discovery of innovative new polymers lies in the difficulty of accurately representing the complex structures of polymeric materials. Although a wide array of hand-designed…

Materials Science · Physics 2022-05-30 Evan R. Antoniuk , Peggy Li , Bhavya Kailkhura , Anna M. Hiszpanski

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao