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Deep learning has been extensively researched in the analysis of pathology whole-slide images (WSIs). However, most existing methods are limited to providing prediction interpretability by locating the model's salient areas in a post-hoc…

Machine Learning · Computer Science 2026-02-04 Zekang Yang , Hong Liu , Xiangdong Wang

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

Facial landmark detection is an important yet challenging task for real-world computer vision applications. This paper proposes an effective and robust approach for facial landmark detection by combining data- and model-driven methods.…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Hongwen Zhang , Qi Li , Zhenan Sun , Yunfan Liu

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Ptychography is a computational method of microscopy that recovers high-resolution transmission images of samples from a series of diffraction patterns. While conventional phase retrieval algorithms can iteratively recover the images, they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Ryuma Nakahata , Shehtab Zaman , Mingyuan Zhang , Fake Lu , Kenneth Chiu

Accurate phenotypic analysis in aquaculture breeding necessitates the quantification of subtle morphological phenotypes. Existing datasets suffer from limitations such as small scale, limited species coverage, and inadequate annotation of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Weizhen Liu , Jiayu Tan , Guangyu Lan , Ao Li , Dongye Li , Le Zhao , Xiaohui Yuan , Nanqing Dong

Hyperspectral imaging is a powerful bioimaging tool which can uncover novel insights, thanks to its sensitivity to the intrinsic properties of materials. However, this enhanced contrast comes at the cost of system complexity, constrained by…

Objective: We investigate whether deep learning techniques for natural language processing (NLP) can be used efficiently for patient phenotyping. Patient phenotyping is a classification task for determining whether a patient has a medical…

Prior work has shown that the order in which different components of the face are learned using a sequential learner can play an important role in the performance of facial expression recognition systems. We propose FaceTopoNet, an…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Mojtaba Kolahdouzi , Alireza Sepas-Moghaddam , Ali Etemad

Computer vision-based methods have valuable use cases in precision medicine, and recognizing facial phenotypes of genetic disorders is one of them. Many genetic disorders are known to affect faces' visual appearance and geometry. Automated…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Ömer Sümer , Fabio Hellmann , Alexander Hustinx , Tzung-Chien Hsieh , Elisabeth André , Peter Krawitz

Automatic phenotype concept recognition from unstructured text remains a challenging task in biomedical text mining research. Previous works that address the task typically use dictionary-based matching methods, which can achieve high…

Computation and Language · Computer Science 2021-01-26 Ling Luo , Shankai Yan , Po-Ting Lai , Daniel Veltri , Andrew Oler , Sandhya Xirasagar , Rajarshi Ghosh , Morgan Similuk , Peter N. Robinson , Zhiyong Lu

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer…

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

Predicting the response of a patient to a cancer treatment is of high interest. Nonetheless, this task is still challenging from a medical point of view due to the complexity of the interaction between the patient organism and the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Mahfoud Chaibi , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Richard J. Chen , Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Jana Lipkova , Muhammad Shaban , Maha Shady , Mane Williams , Bumjin Joo , Zahra Noor , Faisal Mahmood

Fourier ptychography (FP) is a newly developed computational imaging approach that achieves both high resolution and wide field of view by stitching a series of low-resolution images captured under angle-varied illumination. So far, many…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Yongbing Zhang , Yangzhe Liu , Xiu Li , Shaowei Jiang , Krishna Dixit , Xinfeng Zhang , Xiangyang Ji

Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tong Chen , Chao Cao , Yan Zhuang , Minheng Chen , Tianming Liu , Dajiang Zhu

Objective For the UK Biobank standardized phenotype codes are associated with patients who have been hospitalized but are missing for many patients who have been treated exclusively in an outpatient setting. We describe a method for…

Quantitative Methods · Quantitative Biology 2022-12-13 Lu Yang , Sheng Wang , Russ B. Altman