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The retina is the only part of the human body in which blood vessels can be accessed non-invasively using imaging techniques such as digital fundus images (DFI). The spatial distribution of the retinal microvasculature may change with…

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insufficient insulin production or impaired insulin utilization. One of its most severe complications is diabetic retinopathy (DR), a…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Ali El Bellaj , Aya Benradi , Salman El Youssoufi , Taha El Marzouki , Mohammed-Amine Cheddadi

An overview of the applications of deep learning in ophthalmic diagnosis using retinal fundus images is presented. We also review various retinal image datasets that can be used for deep learning purposes. Applications of deep learning for…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sourya Sengupta , Amitojdeep Singh , Henry A. Leopold , Tanmay Gulati , Vasudevan Lakshminarayanan

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

Purpose: To assess whether a generative adversarial network (GAN) could synthesize realistic optical coherence tomography (OCT) images that satisfactorily serve as the educational images for retinal specialists and the training datasets for…

Medical Physics · Physics 2020-06-02 Ce Zheng , Xiaolin Xie , Kang Zhou , Bang Chen , Jili Chen , Haiyun Ye , Wen Li , Tong Qiao , Shenghua Gao , Jianlong Yang , Jiang Liu

Eye diseases have posed significant challenges for decades, but advancements in technology have opened new avenues for their detection and treatment. Machine learning and deep learning algorithms have become instrumental in this domain,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Gauri Naik , Nandini Narvekar , Dimple Agarwal , Nishita Nandanwar , Himangi Pande

A well-known retinal disease that sends blurry visions to the affected patients is Macular Degeneration. This research is based on classifying the healthy and macular degeneration fundus by localizing the affected region of the fundus. A…

Image and Video Processing · Electrical Eng. & Systems 2024-05-03 Tahmim Hossain , Sagor Chandro Bakchy

Automated skin lesion classification using deep learning has shown remarkable accuracy, yet clinical adoption remains limited due to the "black box" nature of these models. We present MelanomaNet, an explainable deep learning system for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Sukhrobbek Ilyosbekov

Glaucoma is one of the ophthalmic diseases that may cause blindness, for which early detection and treatment are very important. Fundus images and optical coherence tomography (OCT) images are both widely-used modalities in diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Zhiyuan Cai , Li Lin , Huaqing He , Xiaoying Tang

Diagnosing glaucoma progression is critical for limiting irreversible vision loss. A common method for assessing glaucoma progression uses a longitudinal series of visual fields (VF) acquired at regular intervals. VF data are characterized…

Applications · Statistics 2018-05-31 Samuel I. Berchuck , Jean-Claude Mwanza , Joshua L. Warren

The significant portion of diabetic patients was affected due to major blindness caused by Diabetic retinopathy (DR). For diabetic retinopathy, lesion segmentation, and detection the comprehensive examination is delved into the deep…

Artificial Intelligence · Computer Science 2024-11-20 Syed Mohd Faisal Malik , Md Tabrez Nafis , Mohd Abdul Ahad , Safdar Tanweer

It is widely known that very small datasets produce overfitting in Deep Neural Networks (DNNs), i.e., the network becomes highly biased to the data it has been trained on. This issue is often alleviated using transfer learning,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-02 Manuel Rey-Area , Emilio Guirado , Siham Tabik , Javier Ruiz-Hidalgo

Convolutional Neural Networks (CNNs) have successfully been used to classify diabetic retinopathy (DR) fundus images in recent times. However, deeper representations in CNNs may capture higher-level semantics at the expense of spatial…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Samuel Ofosu Mensah , Bubacarr Bah , Willie Brink

Fundus images are widely used for diagnosing various eye diseases, such as diabetic retinopathy, glaucoma, and age-related macular degeneration. However, manual analysis of fundus images is time-consuming and prone to errors. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Eric Shah , Jay Patel , Mr. Vishal Katheriya , Parth Pataliya

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

Diabetic macular ischemia (DMI), marked by the loss of retinal capillaries in the macular area, contributes to vision impairment in patients with diabetes. Although color fundus photographs (CFPs), combined with artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Qinghua He , Hongyang Jiang , Danqi Fang , Dawei Yang , Truong X. Nguyen , Anran Ran , Clement C. Tham , Simon K. H. Szeto , Sobha Sivaprasad , Carol Y. Cheung

Diabetic retinopathy is a severe complication of diabetes that can lead to permanent blindness if not treated promptly. Early and accurate diagnosis of the disease is essential for successful treatment. This paper introduces a deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Hossein Shakibania , Sina Raoufi , Behnam Pourafkham , Hassan Khotanlou , Muharram Mansoorizadeh