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Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…

Quantitative Methods · Quantitative Biology 2023-08-14 Alexia Stollmann , Jose Garcia-Guirado , Jae-Sang Hong , Hyungsoon Im , Hakho Lee , Jaime Ortega Arroyo , Romain Quidant

Nanophotonics has become a key enabling technology in biomedicine with great promises in early diagnosis and less invasive therapies. In this context, the unique capability of plasmonic noble metal nanoparticles to concentrate light on the…

Applied Physics · Physics 2017-08-02 Ozlem Yavas , Mikael Svedendahl , Paulina Dobosz , Vanesa Sanz , Romain Quidant

Quantum biosensors offer a promising route to overcome the sensitivity and specificity limitations of conventional biosensing technologies. Their ability to detect biochemical signals at extremely low concentrations makes them strong…

Optics · Physics 2025-08-05 Yasaman Torabi , Shahram Shirani , James P. Reilly

Advances in material science, bio-electronic, and implantable medicine combined with recent requests for eco-friendly materials and technologies inevitably formulate new challenges for nano- and micro-patterning techniques. Overall, the…

Materials Science · Physics 2022-03-09 Artem K. Grebenko , Konstantin A. Motovilov , Anton V. Bubis , Albert G. Nasibulin

Biomarker detection is the key to identifying health risks. However, designing sensitive biosensors in a single-use mode for disease diagnosis remains a major challenge. Here, we report sub-monolayer biolasers with remarkable repeatability…

Despite being extremely old concepts, plasmonics and surface plasmon resonance-based biosensors have been increasingly popular in the recent two decades due to the growing interest in nanooptics and are now of relevant significance in…

Optics · Physics 2023-04-19 Giuseppina Simone

The achievement of all-fibre functional nano-modules for subcellular label-free measurement has long been pursued due to the limitations of manufacturing techniques. In this paper, a compact all-fibre label-free nano-sensor composed of a…

The biological skin enables animals to sense various stimuli. Extensive efforts have been made recently to develop smart skin-like sensors to extend the capabilities of biological skins; however, simultaneous sensing of several types of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Sho Shimadera , Kei Kitagawa , Koyo Sagehashi , Tomoaki Niiyama , Satoshi Sunada

Silicon nanochannel field effect transistor (FET) biosensors are one of the most promising technologies in the development of highly sensitive and label-free analyte detection for cancer diagnostics. With their exceptional electrical…

Quantitative Methods · Quantitative Biology 2014-01-07 Pritiraj Mohanty , Yu Chen , Xihua Wang , Mi K. Hong , Carol L. Rosenberg , David T. Weaver , Shyamsunder Erramilli

We report a theoretical study of clusters of evanescently-coupled 2D whispering-gallery (WG) mode optical micro-cavities (termed "photonic molecules") as chemosensing and biosensing platforms. Photonic molecules (PMs) supporting modes with…

Optics · Physics 2009-11-11 Svetlana V. Boriskina

Integrated chemical and biological sensors give advantages in cost, size and weight reduction and open new prospects for parallel monitoring and analysis. Biosensors based on nanoelectromechanical systems (NEMS) are the most attractive…

Optics · Physics 2019-04-29 Dmitry Yu. Fedyanin , Yury V. Stebunov

Interfacing artificial functional materials and living neuronal tissues is at the forefront of bio-nano-technology. Attempts have been so far based onto microscale processing of metals and inorganic semiconductors as electrodes or…

Biomedical and environmental testing currently require access to highly specialized facilities or extensive training. Current biochemical tests require complex reagents to achieve a simple human readable result such as a color change. This…

Optical nanofibers confine light to subwavelength scales, and are of interest for the design, integration, and interconnection of nanophotonic devices. Here we demonstrate high transmission (> 97%) of the first family of excited modes…

Optics · Physics 2013-08-12 S. Ravets , J. E. Hoffman , L. A. Orozco , S. L. Rolston , G. Beadie , F. K. Fatemi

A micro-ring-resonator (MRR) optical biosensor based on the evanescent field sensing mechanism has been extensively studied due to its high sensitivity and compact device size. However, a suitable on-chip integrated spectrometer device has…

Optics · Physics 2022-07-19 Kyoung Min Yoo , May Hlaing , Sourabh Jain , James Fan , Yue An , Ray T. Chen

This paper briefly describes the device - the phytosensor - for measuring physiological and electrophysiological parameters of plants. This system is developed as a bio-physiological sensor in precise agriculture, as a tool in plant…

Other Computer Science · Computer Science 2022-06-22 Serge Kernbach

The tumor microenvironment (TME) features distinct hallmarks, including acidosis, hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial targets for early cancer biomarker detection, tumor diagnosis,…

In the biochemical sensing field, a fervent research activity related to the development of real time, low cost, compact and high throughput devices for the detection and characterization of natural or synthetic nanoparticles NPs actually…

Optics · Physics 2014-01-13 Clarissa Martina Campanella

There is a growing need for biolabels that can be used in both optical and electron microscopies, are non-cytotoxic, and do not photobleach. Such biolabels could enable targeted nanoscale imaging of sub-cellular structures, and help to…

Biological Physics · Physics 2015-06-23 Mark A. Zurbuchen , Michael P. Lake , Sirus A. Kohan , Belinda Leung , Louis-S. Bouchard

Optical fibre-based sensors measuring refractive index shift in bodily fluids and tissues are versatile and accurate probes of physiological processes. Here, we suggest a refractive index sensor based on a microstructured exposed-core fibre…