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A detailed analysis of ptychography for 3D phase reconstructions of thick specimens is performed. We introduce multi-focus ptychography, which incorporates a 4D-STEM defocus series to enhance the quality of 3D reconstructions along the beam…

We present a method that lowers the dose required for a ptychographic reconstruction by adaptively scanning the specimen, thereby providing the required spatial information redundancy in the regions of highest importance. The proposed…

Computational Physics · Physics 2022-03-30 Marcel Schloz , Johannes Müller , Thomas C. Pekin , Wouter Van den Broek , Christoph T. Koch

Restoring real-world degraded images, such as old photographs or low-resolution images, presents a significant challenge due to the complex, mixed degradations they exhibit, such as scratches, color fading, and noise. Recent data-driven…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Peng Xiao , Hongbo Zhao , Yijun Wang , Jianxin Lin

A solution to the inversion problem of scattering would offer aberration-free diffraction-limited 3D images without the resolution and depth-of-field limitations of lens-based tomographic systems. Powerful algorithms are increasingly being…

Score-based diffusion models provide a powerful way to model images using the gradient of the data distribution. Leveraging the learned score function as a prior, here we introduce a way to sample data from a conditional distribution given…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Hyungjin Chung , Jong Chul Ye

Ptychography is a computational imaging technique that has risen in popularity in the x-ray and electron microscopy communities in the past half decade. One of the reasons for this success is the development of new high performance electron…

Computational Physics · Physics 2023-09-26 Anton Gladyshev , Thomas C. Pekin , Marcel Schloz , Benedikt Haas , Johannes Müller , Christoph T. Koch

Diffusion models have recently gained traction as a powerful class of deep generative priors, excelling in a wide range of image restoration tasks due to their exceptional ability to model data distributions. To solve image restoration…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Xiang Li , Soo Min Kwon , Shijun Liang , Ismail R. Alkhouri , Saiprasad Ravishankar , Qing Qu

Recent advancements in text-guided diffusion models have unlocked powerful image manipulation capabilities. However, applying these methods to real images necessitates the inversion of the images into the domain of the pretrained diffusion…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Daniel Garibi , Or Patashnik , Andrey Voynov , Hadar Averbuch-Elor , Daniel Cohen-Or

Diffusion models have emerged as the new state-of-the-art generative model with high quality samples, with intriguing properties such as mode coverage and high flexibility. They have also been shown to be effective inverse problem solvers,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Hyungjin Chung , Dohoon Ryu , Michael T. McCann , Marc L. Klasky , Jong Chul Ye

Diffusion models are powerful tools for sampling from high-dimensional distributions by progressively transforming pure noise into structured data through a denoising process. When equipped with a guidance mechanism, these models can also…

Machine Learning · Computer Science 2026-05-04 Saeed Mohseni-Sehdeh , Walid Saad , Kei Sakaguchi , Tao Yu

Coherent microscopy techniques provide an unparalleled multi-scale view of materials across scientific and technological fields, from structural materials to quantum devices, from integrated circuits to biological cells. Driven by the…

This article presents a method to perform diffraction tomography in a standard microscope that includes an LED array for illumination. After acquiring a sequence of intensity-only images of a thick sample, a ptychography-based…

Optics · Physics 2015-10-30 Roarke Horstmeyer , Changhuei Yang

Restoring low-resolution text images presents a significant challenge, as it requires maintaining both the fidelity and stylistic realism of the text in restored images. Existing text image restoration methods often fall short in hard…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Chenglu Pan , Xiaogang Xu , Ganggui Ding , Yunke Zhang , Wenbo Li , Jiarong Xu , Qingbiao Wu

3D image reconstruction from a limited number of 2D images has been a long-standing challenge in computer vision and image analysis. While deep learning-based approaches have achieved impressive performance in this area, existing deep…

Computer Vision and Pattern Recognition · Computer Science 2023-10-04 Nivetha Jayakumar , Tonmoy Hossain , Miaomiao Zhang

Tomography is the three-dimensional reconstruction of an object from images taken at different angles. The term classical tomography is used, when the imaging beam travels in straight lines through the object. This assumption is valid for…

Quantitative Methods · Quantitative Biology 2016-10-10 Paul Müller , Mirjam Schürmann , Jochen Guck

Accurate multi-slice reconstruction from limited measurement data is crucial to speed up the acquisition process in medical and scientific imaging. However, it remains challenging due to the ill-posed nature of the problem and the high…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Laurentius Valdy , Richard D. Paul , Alessio Quercia , Zhuo Cao , Xuan Zhao , Hanno Scharr , Arya Bangun

Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Junyan Zhang , Mengxiao Geng , Pinhuang Tan , Yi Liu , Zhili Liu , Bin Huang , Qiegen Liu

In this paper we consider the problem of acoustic inversion in the context of the optoacoustic tomography image reconstruction problem. By leveraging the ability of the recently proposed diffusion models for image generative tasks among…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 M. G. González , M. Vera , A. Dreszman , L. J. Rey Vega

Ptychography, as a powerful lensless imaging method, has become a popular member of the coherent diffractive imaging family over decades of development. The ability to utilize low-dose X-rays and/or fast scans offers a big advantage in a…

Medical Physics · Physics 2024-06-14 Longlong Wu , Shinjae Yoo , Yong S. Chu , Xiaojing Huang , Ian K. Robinson

Iterative ptychographic reconstruction algorithms are widely used for coherent diffractive imaging but can exhibit slow convergence under realistic experimental conditions. We propose a machine learning-augmented approach that accelerates…