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Numerous challenges in science and engineering can be framed as optimization tasks, including the maximization of reaction yields, the optimization of molecular and materials properties, and the fine-tuning of automated hardware protocols.…
We present the MEMA framework for the easy and quick derivation of efficient inference runtimes that minimize external memory accesses for matrix multiplication on TinyML systems. The framework accounts for hardware resource constraints and…
Next-generation real-time compute-intensive applications, such as extended reality, multi-user gaming, and autonomous transportation, are increasingly composed of heterogeneous AI-intensive functions with diverse resource requirements and…
In modern generative-AI workloads, matrix-vector/matrix-matrix multiplications (\emph{MatMul}) dominate the compute and energy cost. Achieving dramatic reductions in energy per token therefore requires a novel, specialized hardware that is…
Quantum simulation, fundamental in quantum algorithm design, extends far beyond its foundational roots, powering diverse quantum computing applications. However, optimizing the compilation of quantum Hamiltonian simulation poses significant…
The emergence of the Next Generation Sequencing increases drastically the volume of transcriptomic data. Although many standalone algorithms and workflows for novel microRNA (miRNA) prediction have been proposed, few are designed for…
Remarkable achievements have been attained by deep neural networks in various applications. However, the increasing depth and width of such models also lead to explosive growth in both storage and computation, which has restricted the…
The rapid increase in symbolic data has underscored the significance of pattern matching and regular expression processing. While nondeterministic finite automata (NFA) are commonly used for these tasks, they are limited to detecting…
Wider adoption of the Grid concept has led to an increasing amount of federated computational, storage and visualisation resources being available to scientists and researchers. Distributed and heterogeneous nature of these resources…
Achieving low-latency consensus in geographically distributed systems remains a key challenge for blockchain and distributed database applications. To this end, there has been significant recent interest in State-Machine-Replication (SMR)…
In this work, a new energy-efficiency performance metric is proposed for MIMO (multiple input multiple output) point-to-point systems. In contrast with related works on energy-efficiency, this metric translates the effects of using finite…
Probabilistic resource adequacy assessment is a cornerstone of modern capacity accreditation. This paper develops a gradient-based framework, in which capacity accreditation is interpreted as the directional derivative of a probabilistic…
Despite the fast advances in high-sigma yield analysis with the help of machine learning techniques in the past decade, one of the main challenges, the curse of dimensionality, which is inevitable when dealing with modern large-scale…
Accurate performance estimation of future many-node machines is challenging because it requires detailed simulation models of both node and network. However, simulating the full system in detail is unfeasible in terms of compute and memory…
To reduce the computation cost and the energy consumption in large language models (LLM), skimming-based acceleration dynamically drops unimportant tokens of the input sequence progressively along layers of the LLM while preserving the…
The miniaturization of transistors down to 5nm and beyond, plus the increasing complexity of integrated circuits, significantly aggravate short channel effects, and demand analysis and optimization of more design corners and modes.…
Payment channel network (PCN) is a layer-two scaling solution that enables fast off-chain transactions but does not involve on-chain transaction settlement. PCNs raise new privacy issues including balance secrecy, relationship anonymity and…
Hardware heterogeneity is here to stay for high-performance computing. Large-scale systems are currently equipped with multiple GPU accelerators per compute node and are expected to incorporate more specialized hardware in the future. This…
Two-stage stochastic programming often discretizes uncertainty into scenarios, but scenario enumeration makes expected recourse evaluation scale at least linearly in the scenario count. We propose qGAN-QAOA, a unified quantum-circuit…
Modern computing platforms tend to deploy multiple GPUs (2, 4, or more) on a single node to boost system performance, with each GPU having a large capacity of global memory and streaming multiprocessors (SMs). GPUs are an expensive…