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Current approaches which are mainly based on the extraction of low-level relations among individual events are limited by the shortage of publicly available labelled data. Therefore, the resulting models perform poorly when applied to a…

Computation and Language · Computer Science 2020-11-30 Farhad Moghimifar , Gholamreza Haffari , Mahsa Baktashmotlagh

Knowledge Graph Completion (KGC) aims to predict the missing information in the (head entity)-[relation]-(tail entity) triplet. Deep Neural Networks have achieved significant progress in the relation prediction task. However, most existing…

Computation and Language · Computer Science 2024-08-15 Pengjie Liu

In retrosynthetic planning, the huge number of possible routes to synthesize a complex molecule using simple building blocks leads to a combinatorial explosion of possibilities. Even experienced chemists often have difficulty to select the…

Artificial Intelligence · Computer Science 2023-06-13 Siqi Hong , Hankz Hankui Zhuo , Kebing Jin , Guang Shao , Zhanwen Zhou

Detecting probable Drug Target Interaction (DTI) is a critical task in drug discovery. Conventional DTI studies are expensive, labor-intensive, and take a lot of time, hence there are significant reasons to construct useful computational…

Quantitative Methods · Quantitative Biology 2022-10-24 Tanya Liyaqat , Tanvir Ahmad , Chandni Saxena

Target tracking faces the challenge in coping with large volumes of data which requires efficient methods for real time applications. The complexity considered in this paper is when there is a large number of measurements which are required…

Computation · Statistics 2015-08-03 Allan De Freitas , François Septier , Lyudmila Mihaylova , Simon Godsill

Traditional biomedical version of embeddings obtained from pre-trained language models have recently shown state-of-the-art results for relation extraction (RE) tasks in the medical domain. In this paper, we explore how to incorporate…

Computation and Language · Computer Science 2020-12-23 Ishani Mondal

Drug-target interaction (DTI) prediction plays a very important role in drug development and drug discovery. Biochemical experiments or \textit{in vitro} methods are very expensive, laborious and time-consuming. Therefore, \textit{in…

Machine Learning · Computer Science 2018-05-04 Ratha Pech , Dong Hao , Yan-Li Lee , Maryna Po , Tao Zhou

Surgical triplet recognition, which involves identifying instrument, verb, target, and their combinations, is a complex surgical scene understanding challenge plagued by long-tailed data distribution. The mainstream multi-task learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yiyi Zhang , Yuchen Yuan , Ying Zheng , Jialun Pei , Jinpeng Li , Zheng Li , Pheng-Ann Heng

Multi-view clustering can explore consistent information from different views to guide clustering. Most existing works focus on pursuing shallow consistency in the feature space and integrating the information of multiple views into a…

Machine Learning · Computer Science 2023-05-18 Yiyang Zhou , Qinghai Zheng , Wenbiao Yan , Yifei Wang , Pengcheng Shi , Jihua Zhu

Structure-Based Drug Design (SBDD) is a powerful strategy in computational drug discovery, utilizing three-dimensional protein structures to guide the design of molecules with improved binding affinity. However, capturing complex…

Machine Learning · Computer Science 2025-11-18 Long Xu , Yongcai Chen , Fengshuo Liu , Yuzhong Peng

Trajectory prediction is crucial for the reliability and safety of autonomous driving systems, yet it remains a challenging task in complex interactive scenarios due to noisy trajectory observations and intricate agent interactions.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Wenyi Xiong , Jian Chen , Ziheng Qi , Wenhua Chen

Motivation: Drug combination is a sensible strategy for disease treatment by improving the efficacy and reducing concomitant side effects. Due to the large number of possible combinations among candidate compounds, exhaustive screening is…

Quantitative Methods · Quantitative Biology 2020-02-26 Liang Yu , Mingfei Xia , Lin Gao

Distance metric learning based on triplet loss has been applied with success in a wide range of applications such as face recognition, image retrieval, speaker change detection and recently recommendation with the CML model. However, as we…

Information Retrieval · Computer Science 2019-09-25 Viet-Anh Tran , Romain Hennequin , Jimena Royo-Letelier , Manuel Moussallam

The generation of connectional brain templates (CBTs) has recently garnered significant attention for its potential to identify unique connectivity patterns shared across individuals. However, existing methods for CBT learning such as…

Machine Learning · Computer Science 2025-08-18 Mayssa Soussia , Mohamed Ali Mahjoub , Islem Rekik

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Objective: Medical relations are the core components of medical knowledge graphs that are needed for healthcare artificial intelligence. However, the requirement of expert annotation by conventional algorithm development processes creates a…

Machine Learning · Computer Science 2020-09-09 Yucong Lin , Keming Lu , Yulin Chen , Chuan Hong , Sheng Yu

In drug discovery, identifying drug-target interactions (DTIs) via experimental approaches is a tedious and expensive procedure. Computational methods efficiently predict DTIs and recommend a small part of potential interacting pairs for…

Quantitative Methods · Quantitative Biology 2022-01-19 Bin Liu , Grigorios Tsoumakas

Predicting agents' future trajectories plays a crucial role in modern AI systems, yet it is challenging due to intricate interactions exhibited in multi-agent systems, especially when it comes to collision avoidance. To address this…

Robotics · Computer Science 2021-03-29 Xu Xie , Chi Zhang , Yixin Zhu , Ying Nian Wu , Song-Chun Zhu

Recently, several studies have shown that utilizing contextual information to perceive target states is crucial for object tracking. They typically capture context by incorporating multiple video frames. However, these naive frame-context…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Chenlong Xu , Bineng Zhong , Qihua Liang , Yaozong Zheng , Guorong Li , Shuxiang Song

Active learning enables the efficient construction of a labeled dataset by labeling informative samples from an unlabeled dataset. In a real-world active learning scenario, considering the diversity of the selected samples is crucial…

Machine Learning · Computer Science 2022-07-15 Yeachan Kim , Bonggun Shin